Primary immunodeficiency
primary immodeficiency, inborn error of immunity, immune dysregulation
Research aim
To address unmet medical needs by detecting novel primary immunodeficiency, and improving clinical practice by optimizing diagnosis, prognosis and treatment of disease.
About us
Our research is translational in nature covering fundamental laboratory, human clinical studies and trials. To support this translational focus our research is structured by a complementary team of physicians (MD, PhDs) and fundamental researchers (PhDs), each with their own expertise. PhD students, technicians and research nurses are frequently involved in the projects, supported by students and trainees. Our research is embedded in the strategic research programmes Infection & Immunity and Child Health. Our own unique patient cohorts from the departments of Rheumatology & Clinical Immunology, Infectious Diseases and Pediatric Immunology & Infectious Diseases, is core to our science and national and international collaborations. We align with the ambitions as a Jeffrey Modell Foundation center, expertise centers for rare disease (ECZA) and European Reference Networks (ERN-RITA and ERN-ReCONNET). We collaborate within the different laboratories within the Center of Translation Immunology, the Central Diagnostic Laboratory, and the Departments of Rheumatology & Clinical Immunology and Medical Microbiology in the UMC, which provides direct support for our investigator and industry initiated clinical studies allowing implementation of state-of-the-art technologies such as proteomics, next generation sequencing and imaging. As such, we collaborate with both academic and many leading industrial partners within the field.