Profile photo Joris van Montfrans

Joris van Montfrans

Assistant Professor - medical

Strategic program(s):

Biography

Dr. Joris van Montfrans completed his medical study at the Rijks Universiteit Leiden and his PhD at the Vrije Universiteit Amsterdam. He performed his pediatric training at the UMC Utrecht and at Tygerberg Hospital in Cape Town, South Africa. He is a consultant in pediatric immunology since 2009. Dr. van Montfrans works as a clinical doctor and as a researcher in primary immunodeficiencies. The research areas he is involved in include clinical studies into long term complications of antibody deficiencies, and genetic causes of primary immune deficiencies. Together with a consortium of researchers from immunology- and genetic departments, NGS based testing for diagnosis of immune deficiencies was developed, studied and implemented. He is the principal investigator for a national study efficiacy of early screening for genetic causes (ZonMW funded) of immundeficiencies. He is also the principal investigator in a study into auto-immune complications in CVID. He is secretary of the National Working Party for Immnunodeficiencies and member of the eGLILD consortium steering committee. He is an active teacher, training medical students and organizing and lecturing in EUREKA summer schools.

Research groups

Pediatric immunology team

Research aim

The pediatric immunology team focuses on the under-explored research field of immune response modification for the prevention of immune-driven diseases. The goal of our research is to develop interventions that can prevent disease manifestations.
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Primary immunodeficiency

Research aim

To address unmet medical needs by detecting novel primary immunodeficiency, and improving clinical practice by optimizing diagnosis, prognosis and treatment of disease.
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Recent publications

JAK inhibitor treatment for inborn errors of JAK/STAT signaling Marco Fischer, Peter Olbrich, Jérôme Hadjadj, Volker Aumann, Shahrzad Bakhtiar, Vincent Barlogis, Philipp von Bismarck, Markéta Bloomfield, Claire Booth, Emmeline P. Buddingh, Deniz Cagdas, Martin Castelle, Alice Y. Chan, Shanmuganathan Chandrakasan, Kritika Chetty, Pierre Cougoul, Etienne Crickx, Jasmeen Dara, Angela Deyà-Martínez, Susan Farmand, Renata Formankova, Andrew R. Gennery, Luis Ignacio Gonzalez-Granado, David Hagin, Leif Gunnar Hanitsch, Jana Hanzlikovà, Fabian Hauck, José Ivorra-Cortés, Kai Kisand, Ayca Kiykim, Julia Körholz, Timothy Ronan Leahy, Joris van Montfrans, Zohreh Nademi, Brigitte Nelken, Suhag Parikh, Silvi Plado, Jan Ramakers, Antje Redlich, Frédéric Rieux-Laucat, Jacques G. Rivière, Yulia Rodina, Pérsio Roxo Júnior, Sarah Salou, Catharina Schuetz, Anna Shcherbina, Mary A. Slatter, Fabien Touzot, Ekrem Unal, Arjan C. Lankester, Siobhan Burns, Mikko R.J. Seppänen, Olaf Neth, Michael H. Albert, Stephan Ehl, Bénédicte Neven, Carsten Speckmann
Journal of Allergy and Clinical Immunology, 2024, vol. 153, p.275-286.e18
Wiskott-Aldrich syndrome Tanja C. Vallée, Jannik S. Glasmacher, Hannes Buchner, Peter D. Arkwright, Uta Behrends, Anastasia Bondarenko, Michael J. Browning, David Buchbinder, Alessandro Cattoni, Liudmyla Chernyshova, Peter Ciznar, Theresa Cole, Wojciech Czogała, Gregor Dueckers, John David M. Edgar, Fatih Erbey, Anders Fasth, Francesca Ferrua, Renata Formankova, Eleonora Gambineri, Andrew R. Gennery, Frederick D. Goldman, Luis I. Gonzalez-Granado, Carsten Heilmann, Tarja Heiskanen-Kosma, Hanna Juntti, Leena Kainulainen, Hirokazu Kanegane, Neslihan E. Karaca, Sara S. Kilic, Christoph Klein, Sylwia Kołtan, Irina Kondratenko, Isabelle Meyts, Gulnara M. Nasrullayeva, Lucia D. Notarangelo, Srdjan Pasic, Isabelle Pellier, Claudio Pignata, Siraj Misbah, Ansgar Schulz, Gesmar R. Segundo, Anna Shcherbina, Mary Slatter, Robert Sokolic, Pere Soler-Palacin, Polina Stepensky, Joris M. van Montfrans, Samppa Ryhänen, Beata Wolska-Kuśnierz, John B. Ziegler, Xiaodong Zhao, Alessandro Aiuti, Hans D. Ochs, Michael H. Albert
Blood, 2024, vol. 143, p.2504-2516
Humoral and cellular immunogenicity, effectiveness and safety of COVID-19 mRNA vaccination in patients with pediatric rheumatic diseases Mohamad Hamad Saied, Joeri W van Straalen, Sytze de Roock, Frans M Verduyn Lunel, Jelle de Wit, Lia G H de Rond, Erika Van Nieuwenhove, Bas J Vastert, Joris M van Montfrans, Annet van Royen-Kerkhof, Gerrie C J de Joode-Smink, Joost F Swart, Nico M Wulffraat, Marc H A Jansen
Vaccine, 2024, vol. 42, p.1145-1153
Pulmonary Computed Tomography Screening Frequency in Primary Antibody Deficiency Bas M Smits, Sharisa L Boland, Marjolein E Hol, Rana Dandis, Helen Leavis, Pim A de Jong, Sabine M P J Prevaes, Firdaus A A Mohamed Hoesein, Joris M van Montfrans, Pauline M Ellerbroek
Journal of Allergy and Clinical Immunology: In Practice, 2024, vol. 12, p.1037-1048.e3
Impact of newborn screening for SCID on the management of congenital athymia Evey Howley, Zainab Golwala, Matthew Buckland, Federica Barzaghi, Sujal Ghosh, Scott Hackett, Rosie Hague, Fabian Hauck, Ursula Holzer, Adam Klocperk, Minna Koskenvuo, Nufar Marcus, Antonio Marzollo, Malgorzata Pac, Jan Sinclair, Carsten Speckmann, Maarja Soomann, Lynne Speirs, Sneha Suresh, Sophie Taque, Joris van Montfrans, Horst von Bernuth, Brynn K. Wainstein, Austen Worth, E. Graham Davies, Alexandra Y. Kreins
Journal of Allergy and Clinical Immunology, 2023, vol. 153, p.330-334
Diagnostic testing for interstitial lung disease in common variable immunodeficiency Heba M. Bintalib, Annick van de Ven, Joseph Jacob, Jesper Rømhild Davidsen, Børre Fevang, Leif G. Hanitsch, Marion Malphettes, Joris van Montfrans, Paul J. Maglione, Cinzia Milito, John Routes, Klaus Warnatz, John R. Hurst
Frontiers in Immunology, 2023, vol. 14

Fellowships & Awards

2020: Jeffrey Modell Foundation C.H.I.L.D.R.E.N! Research Program grant