Nanda Verhoeven-Duif

Full Professor

Strategic program(s):

Contact

nverhoev@umcutrecht.nl

Pure profile

Research groups

Clinical metabolomics and metabolic diagnostics

Research aim

Our research, focusing on metabolic disturbances, aims to improve diagnostics, to enable treatments, and to contribute to the development of novel therapies. The impact extends from individual patient care to a broader understanding of human disease.

Go to group

Recent publications

All publications

mTORC1 restricts TFE3 activity by auto-regulating its presence on lysosomes Susan Zwakenberg, Denise Westland, Robert M. van Es, Holger Rehmann, Jasper Anink, Jolita Ciapaite, Marjolein Bosma, Ellen Stelloo, Nalan Liv, Paula Sobrevals Alcaraz, Nanda M. Verhoeven-Duif, Judith J.M. Jans, Harmjan R. Vos, Eleonora Aronica, Fried J.T. Zwartkruis
Molecular Cell, 2024, vol. 84, p.4368-4384.e6

Direct Infusion Mass Spectrometry to Rapidly Map Metabolic Flux of Substrates Labeled with Stable Isotopes Nils W F Meijer, Susan Zwakenberg, Johan Gerrits, Denise Westland, Arif I Ardisasmita, Sabine A Fuchs, Nanda M Verhoeven-Duif, Judith J M Jans, Fried J T Zwartkruis
Metabolites, 2024, vol. 14

The malate-aspartate shuttle is important for de novo serine biosynthesis Melissa H Broeks, Nils W F Meijer, Denise Westland, Marjolein Bosma, Johan Gerrits, Hannah M German, Jolita Ciapaite, Clara D M van Karnebeek, Ronald J A Wanders, Fried J T Zwartkruis, Nanda M Verhoeven-Duif, Judith J M Jans
Cell Reports, 2023, vol. 42, p.1-18

Metabolic Alterations in NADSYN1-Deficient Cells Nils W F Meijer, Johan Gerrits, Susan Zwakenberg, Fried J T Zwartkruis, Nanda M Verhoeven-Duif, Judith J M Jans
Metabolites, 2023, vol. 13

A one-year pilot study comparing direct-infusion high resolution mass spectrometry based untargeted metabolomics to targeted diagnostic screening for inherited metabolic diseases Anke P Willems, Maria van der Ham, Birgit G M Schiebergen-Bronkhorst, Mirjam van Aalderen, Martina M J de Barse, Fini E De Gruyter, Ilja N van Hoek, Mia L Pras-Raves, Monique G M de Sain-van der Velden, Hubertus C M T Prinsen, Nanda M Verhoeven-Duif, Judith J M Jans
Frontiers in Molecular Biosciences, 2023, vol. 10

Maintenance of cellular vitamin B ₆ levels and mitochondrial oxidative function depend on pyridoxal 5′-phosphate homeostasis protein Jolita Ciapaite, Carlo W T van Roermund, Marjolein Bosma, Johan Gerrits, Sander M Houten, Lodewijk IJlst, Hans R Waterham, Clara D M van Karnebeek, Ronald J A Wanders, Fried J T Zwartkruis, Judith J Jans, Nanda M Verhoeven-Duif
The Journal of biological chemistry, 2023, vol. 299

External positions

Lid scientific board - het beoordelen van subsidie-aanvragen bij Metakids. - Metakids

Lid raad van toezicht - Geen direct raakvlak - GGz Centraal