Karin de Winter-de Groot

PHD Candidate - Medical

Strategic program(s):

Contact

kwinter@umcutrecht.nl

Pure profile

Research groups

Cellular disease models

Research aim

To develop patient-derived cell models to understand the molecular mechanisms of disease, to identify and validate targets for treatment, and to develop drugs and precision medicine applications.

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Pediatric pulmonology

Research aim

We unravel biological, clinical and psychosocial aspects of lung diseases like Cystic Fibrosis, Primary Ciliary Dyskinesia and oncology to continuously improve diagnosis and treatment by implementing latest scientific insights into clinical care.

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Recent publications

All publications

Impact of COVID-19 infection on lung function and nutritional status amongst individuals with cystic fibrosis Julie Semenchuk, Yumi Naito, Susan C. Charman, Siobhán B. Carr, Stephanie Y. Cheng, Bruce C. Marshall, Albert Faro, Alexander Elbert, Hector H. Gutierrez, Christopher H. Goss, Bulent Karadag, Pierre Régis Burgel, Carla Colombo, Marco Salvatore, Rita Padoan, Géraldine Daneau, Satenik Harutyunyan, Nataliya Kashirskaya, Laura Kirwan, Peter G. Middleton, Rasa Ruseckaite, Isabelle de Monestrol, Lutz Naehrlich, Pedro Mondejar-Lopez, Andreas Jung, Jacqui van Rens, Egil Bakkeheim, Annalisa Orenti, Domenique Zomer-van Ommen, Luiz Vicente RF da Silva-Filho, Flavia Fonseca Fernandes, Marco Zampoli, Anne L. Stephenson, Irena Kasmi, Ouardia Drali, Sabine Burghart, Andrea Lakatos-Krepcik, Johannes Eder, Peter Jaksch, Katharina Kainz, Margit Kallinger, Alexander Leitner, Marta Mozdzen, Andreas Pfleger, Sabine Renner, Martin Stadlinger, Christina Thir, Emil Nuriyev, Harry Heijerman, Renske van der Meer, Karin de Winter-de Groot,
Journal of Cystic Fibrosis, 2024, vol. 23, p.815-822

Reply to Sujoy Khan Lisa P van der Rijst, Karin M de Winter-de Groot, Marjolein S de Bruin-Weller, Marlies de Graaf
Pediatric Allergy and Immunology, 2024, vol. 35

Letter to the editor E. De Wachter, J. C. Davies, N. J. Simmonds, C. Castellani, K. M. de Winter-de Groot, A. Munck, M. Proesmans, K. W. Southern, J. Barben
Journal of Cystic Fibrosis, 2023, vol. 23, p.176-177

FDA-approved drug screening in patient-derived organoids demonstrates potential of drug repurposing for rare cystic fibrosis genotypes E. de Poel, S. Spelier, M. C. Hagemeijer, P. van Mourik, S. W.F. Suen, A. M. Vonk, J. E. Brunsveld, G. N. Ithakisiou, E. Kruisselbrink, H. Oppelaar, G. Berkers, K. M. de Winter de Groot, S. Heida-Michel, S. R. Jans, H. van Panhuis, M. Bakker, R. van der Meer, J. Roukema, E. Dompeling, E. J.M. Weersink, G. H. Koppelman, A. R. Blaazer, J. E. Muijlwijk-Koezen, C. K. van der Ent, J. M. Beekman
Journal of Cystic Fibrosis, 2023, vol. 22, p.548-559

16S rRNA-Based Microbiota Profiling Assists Conventional Culture Analysis of Airway Samples from Pediatric Cystic Fibrosis Patients Maartje Kristensen, Emma M de Koff, Mei Ling Chu, Simone Groendijk, Gerdien A Tramper-Stranders, Karin M de Winter-de Groot, Hettie M Janssens, Harm A Tiddens, Mireille van Westreenen, Elisabeth A M Sanders, Bert H G M Arets, Cornelis K van der Ent, Sabine M P J Prevaes, Debby Bogaert
Microbiology spectrum, 2023, vol. 11, p.1-8

Organoid-guided synergistic treatment of minimal function CFTR mutations with CFTR modulators, roflumilast and simvastatin Sacha Spelier, Karin de Winter-de Groot, Natascha Keijzer-Nieuwenhuijze, Yves Liem, Kors van der Ent, Jeffrey Beekman, Lieke S. Kamphuis
The European respiratory journal, 2023, vol. 63

External positions

Voorzitter Sectie Kinderlongzieken van de NVK - Wetenschappelijke vakvereniging - Nederlands Vereniging voor Kindergeneeskunde