Profile photo Julia Drylewicz

Julia Drylewicz

Assistant Professor

Strategic program(s):

Biography

Julia Drylewicz is an Assistant Professor within the Computational Immunology Core of the Center for Translational Immunology (CTI) of the UMC Utrecht focusing on biomarkers discovery and bringing methodological support to researchers from the design of a project to its publication.

Since 2014, she collaborates with many groups on multidisciplinary projects within the CTI and aim at closing the gap between experimental and theoretical work by using biostatistics, bioinformatics and computational approaches. Some of her most recent projects involve modeling cell homeostasis in human, defining the optimal time of maternal vaccination for RSV infection, determining endotypes of atopic dermatitis patients based on serum biomarkers measured by Luminex and analyses of Olink data.  

She was trained in Biostatistics and Epidemiology at Bordeaux School of Public Health (ISPED, France) and graduated in Biomathematics from Paris V University (France) in 2006. She obtained her PhD in biostatistics at Bordeaux University (France) in 2009. From 2010 till 2014, she performed postdoctoral research in computational and quantitative immunology under the supervision of José Borghans in the Department of Immunology at the UMC Utrecht and collaborated with Rob de Boer in the Utrecht Center for Quantitative Immunology at Utrecht University. Her research focused on quantifying cell dynamics in health and disease using mathematical modeling to analyze stable-isotope labeling experiments.

Research groups

Computational immunology core

Research aim

We bring together bioinformaticians, biostatisticians and mathematical modelers to develop new methodologies to interpret the complex datasets that are being generated by immunologists, and form a bridge between the wet and dry labs and the clinic.

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Recent publications

Disagreement FDA and EMA on RSV Maternal Vaccination Joukje E Willemsen, José A M Borghans, Louis J Bont, Julia Drylewicz
The Pediatric infectious disease journal, 2024, vol. 43, p.e1-e2
Highly multiplexed spatial analysis identifies tissue-resident memory T cells as drivers of ulcerative and immune checkpoint inhibitor colitis Mick J.M. van Eijs, José J.M. ter Linde, Matthijs J.D. Baars, Mojtaba Amini, Miangela M. Laclé, Eelco C. Brand, Eveline M. Delemarre, Julia Drylewicz, Stefan Nierkens, Rik J. Verheijden, Bas Oldenburg, Yvonne Vercoulen, Karijn P.M. Suijkerbuijk, Femke van Wijk
iScience, 2023, vol. 26
Biomarkers in atopic dermatitis Daphne Bakker, Marjolein de Bruin-Weller, Julia Drylewicz, Femke van Wijk, Judith Thijs
Journal of Allergy and Clinical Immunology, 2023, vol. 151, p.1163-1168
A Network of Serum Proteins Predict the Need for Systemic Immunomodulatory Therapy at Diagnosis in Noninfectious Uveitis Jonas J W Kuiper, Fleurieke H Verhagen, Sanne Hiddingh, Roos A W Wennink, Anna M Hansen, Kerry A Casey, Imo E Hoefer, Saskia Haitjema, Julia Drylewicz, Mehmet Yakin, H Nida Sen, Timothy R D J Radstake, Joke H de Boer
Ophthalmology science, 2022, vol. 2, p.1-9
Thrombosis pathways in COVID-19 vs. influenza-associated ARDS Emma Rademaker, Dennis J Doorduijn, Nuray Kusadasi, Coen Maas, Julia Drylewicz, Albert Huisman, Imo E Hoefer, Marc J M Bonten, Lennie P G Derde, Suzan H M Rooijakkers, Olaf L Cremer
Journal of thrombosis and haemostasis : JTH, 2022, vol. 20, p.1206-1212