Bartels

Associate Professor - medical

Strategic program(s):

Biography

Marije Bartels, MD, PhD is a pediatric hematologist working at the Pediatric Hematology department of the Wilhelmina Children’s Hospital/UMC Utrecht. She has a special interest in inherited bone marrow failure syndromes, and rare anemias. Following her PhD thesis in 2014, she continued her research on epigenomic regulation of myeloid disorders and on the biology of inherited bone marrow failure syndromes with a special focus on Diamond-Blackfan anemia and Severe Congenital Neutropenia.

Marije is an active member of national and international committees concerning bone marrow failure disorders in children (including PNH), and red blood cell pathology.

Strategic program(s):

Contact

mbartel2@umcutrecht.nl

Pure profile

Research groups

Diamond-Blackfan Anemia syndrome research group

Research aim

We have developed patient iPSC models to increase our understanding of DBAS disease biology and design novel targeted therapies. In combination with the detailed clinical data from our DBAS registry we aim to improve lifelong clinical management.

Go to group

Recent publications

All publications

Metabolic blood profile and response to treatment with the pyruvate kinase activator mitapivat in patients with sickle cell disease Myrthe J van Dijk, Titine J J Ruiter, Sigrid van der Veen, Minke A E Rab, Brigitte A van Oirschot, Jennifer Bos, Cleo Derichs, Anita W Rijneveld, Marjon H Cnossen, Erfan Nur, Bart J Biemond, Marije Bartels, Roger E G Schutgens, Wouter W van Solinge, Judith J M Jans, Eduard J van Beers, Richard van Wijk
Hemasphere, 2024, vol. 8

Diagnosis, treatment, and surveillance of Diamond-Blackfan anaemia syndrome Marcin W. Wlodarski, Adrianna Vlachos, Jason E. Farrar, Lydie M. Da Costa, Antonis Kattamis, Irma Dianzani, Cristina Belendez, Sule Unal, Hannah Tamary, Ramune Pasauliene, Dagmar Pospisilova, Josu de la Fuente, Deena Iskander, Lawrence Wolfe, Johnson M. Liu, Akiko Shimamura, Katarzyna Albrecht, Birgitte Lausen, Anne Grete Bechensteen, Ulf Tedgard, Alexander Puzik, Paola Quarello, Ugo Ramenghi, Marije Bartels, Heinz Hengartner, Roula A. Farah, Mahasen Al Saleh, Amir Ali Hamidieh, Wan Yang, Etsuro Ito, Hoon Kook, Galina Ovsyannikova, Leo Kager, Pierre Emmanuel Gleizes, Jean Hugues Dalle, Brigitte Strahm, Charlotte M. Niemeyer, Jeffrey M. Lipton, Thierry M. Leblanc,
The Lancet Haematology, 2024, vol. 11, p.e368-e382

COVID-19 disease in patients with chronic neutropenia Michail Spanoudakis, Deniz Yilmaz Karapinar, David Dale, Audrey Anna Bolyard, Emily Tran, Jelena Roganovic, Marije Bartels, Suncica Kapor, Daniela Guardo, Joanne Yacobovich, Christer Nilsson, Valentino Bezzerri, Marco Cipolli, Anna Pegoraro, Emil Aleksov, Margarita Guenova, Carlo Dufour, Francesca Fioredda, Helen A. Papadaki, Jan Palmblad
British Journal of Haematology, 2024, vol. 204, p.2480-2483

Pharmacokinetics, pharmacodynamics, efficacy, and safety of ravulizumab in pediatric paroxysmal nocturnal hemoglobinuria Satheesh Chonat, Alexander Kulagin, Alexey Maschan, Marije Bartels, Jochen Buechner, Rowena Punzalan, Michael Richards, Masayo Ogawa, Eden Hicks, Ji Yu, André Baruchel, Austin G Kulasekararaj
Blood Advances, 2024, vol. 8, p.2813-2824

Activation of pyruvate kinase as therapeutic option for rare hemolytic anemias Myrthe J van Dijk, Jonathan R A de Wilde, Marije Bartels, Kevin H M Kuo, Andreas Glenthøj, Minke A E Rab, Eduard J van Beers, Richard van Wijk
Blood Reviews, 2023, vol. 61

HAX1-related congenital neutropenia Denys Pogozhykh, Deniz Yilmaz Karapinar, Maksim Klimiankou, Natali Gerschmann, Georg Ebetsberger-Dachs, Jan Palmblad, Göran Carlsson, Tania Masmas, Sally Kinsey, Marije Bartels, Sabine Mellor-Heineke, Karl Welte, Julia Skokowa, Cornelia Zeidler
British Journal of Haematology, 2023, vol. 202, p.393-411

Fellowships & Awards

2018: De rol van ijzer in de functie van het jonge immuunsysteem: wel of niet suppleren?