The mission within this research subject focuses on understanding the pathophysiology of immune-mediated diseases (IMIDs), infectious diseases and pain as well as dissecting the complex interactions between host and pathogen at a molecular level. Key research areas include:
- Immune pathology of infections: Here we explore how pathogens induce disease or specific disease states is fundamental for creating effective therapeutic strategies.
- Microbiomics: Here we examine the role of the microbiome (the community of bacteria living on the skin, in the gut, or in the airways) in health and disease. Our research aims to understand how the microbiome composition influences diseases and their progression.
- Pain: Here we focus on interactions between the immune system and the sensory nervous system. By understanding which neuro-immune interactions contribute to chronic pain development, we aim to develop innovative pain diagnostics and curative treatments in patients with nerve injury, chronic inflammation, after surgery, and osteoarthritis.
- Pathophysiology of IMIDs: Here we address IMIDs through multidisciplinary research into the immune system’s regulation and dysregulation. By integrating immune system studies, we seek to classify patients based on underlying mechanisms and identify treatable traits, moving towards personalized treatment strategies focused on immune activation patterns.
