Circulatory Health Cerebrovascular disease

Cerebrovascular disease

Diagnosis, treatment, and prognosis of patients with acute ischemic stroke, carotid artery disease, intracranial vasculopathy, genetics of stroke, and TIA.

Research interest

The main research interest of the research theme Cerebrovascular disease concerns the diagnosis, treatment, and prognosis of patients with acute ischemic stroke, carotid artery disease, intracranial vasculopathy, genetics of stroke, and TIA. The focus lies on

Intervention and imaging in ischemic stroke;
Secondary prevention focusing on carotid occlusion and stenosis and vertebral artery stenosis, both with respect to clinical epidemiology and medical treatment;
Vascular cognitive impairment and neuropsychology, in which the association with other types of dementia and with diabetes is investigated with respect to genetics and imaging techniques; and
The association of ischemic stroke and intracerebral vasculopathy and rare neurovascular diseases.

Research objectives:

Development of models that predict outcome based on multiparametric imaging data.
Development of non-invasive brain stimulation to improve functional recovery after stroke.
Identification and investigation of novel genes that play a role in the aetiology of ischemic stroke.
Development of novel CT and MR imaging techniques for intracranial vessels, brain perfusion and parenchymal damage.

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Contact

circulatoryhealth@umcutrecht.nl