Utrecht Monoclonal Antibody Facility (UMAB)

About our applications

UMAB offers end-to-end monoclonal antibody development, from target design to high-affinity, functionally validated antibodies.
Using a unique immunization and screening workflow, we support academic research with reliable and scalable antibody solutions.

Our applications

  • Unique immunization method to generate high affinity antibodies to surface molecules (KD 10-10 to 10-11 )
  • 5000-10000 generated hybridomas screened for binding
  • Screening on FACS, selection of top 5-10 antibodies
  • From target sequence to mouse hybridoma’s in 6-9 months
  • Sequencing of hybridomas
  • Chimerization on 5-10 mAbs within 3-4 months
  • Produce antibodies of patented sequences for academic use

UMAB afbeelding applications