Yvonne Vercoulen

Associate Professor

Strategic program(s):

Biography

See Vercoulen lab website >

Strategic program(s):

Contact

yvercou2@umcutrecht.nl

Pure profile

Research groups

Inflammatory bowel diseases

Research aim

Our research is focused on the elucidation of the pathogenesis of Inflammatory bowel diseases (IBD), personalized medicine and on a severe complication of IBD: colitis-associated colorectal carcinoma.

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Tissue immune microenvironment: spatial biology

Research aim

Understand the immune mechanisms that underly cancer and inflammatory disease, to impact diagnosis and therapeutic strategies in patients.

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Tissue immunology

Research aim

Our mission is to comprehensively understand, monitor, and target immune-mediated inflammatory diseases such as IBD, AD and systemic autoimmune diseases. We aim to unravel (tissue) immune dysregulation and induce long-lasting disease modification.

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Primary immunodeficiency

Research aim

To address unmet medical needs by detecting novel primary immunodeficiency, and improving clinical practice by optimizing diagnosis, prognosis and treatment of disease.

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Recent publications

All publications

Dietary cystine restriction increases the proliferative capacity of the small intestine of mice Judith C.W. de Jong, Kristel S. van Rooijen, Edwin C.A. Stigter, M. Can Gülersönmez, Marcel R. de Zoete, Janetta Top, Matthijs J.D. Baars, Yvonne Vercoulen, Folkert Kuipers, Saskia W.C. Van Mil, Noortje Ijssennagger
PLoS ONE, 2024, vol. 19

Highly multiplexed spatial analysis identifies tissue-resident memory T cells as drivers of ulcerative and immune checkpoint inhibitor colitis Mick J.M. van Eijs, José J.M. ter Linde, Matthijs J.D. Baars, Mojtaba Amini, Miangela M. Laclé, Eelco C. Brand, Eveline M. Delemarre, Julia Drylewicz, Stefan Nierkens, Rik J. Verheijden, Bas Oldenburg, Yvonne Vercoulen, Karijn P.M. Suijkerbuijk, Femke van Wijk
iScience, 2023, vol. 26

Stromal localization of inactive CD8 + T cells in metastatic mismatch repair deficient colorectal cancer. Emre Küçükköse, Matthijs J.D. Baars, Mojtaba Amini, Suzanna J. Schraa, Evelien Floor, Guus M. Bol, Inne H.M. Borel Rinkes, Jeanine M.L. Roodhart, Miriam Koopman, Jamila Laoukili, Onno Kranenburg, Yvonne Vercoulen
British Journal of Cancer, 2023, vol. 130, p.213-223

MATISSE Daniëlle Krijgsman, Neeraj Sinha, Matthijs J.D. Baars, Stephanie van Dam, Mojtaba Amini, Yvonne Vercoulen
STAR protocols, 2022, vol. 3, p.1-36

Multiplex Tissue Imaging Stephanie van Dam, Matthijs J.D. Baars, Yvonne Vercoulen
Cancers, 2022, vol. 14, p.1-30

Ablation of liver Fxr results in an increased colonic mucus barrier in mice Noortje Ijssennagger, Kristel S. van Rooijen, Stefanía Magnúsdóttir, José M. Ramos Pittol, Ellen C.L. Willemsen, Marcel R. de Zoete, Matthijs J.D. Baars, Paul B. Stege, Carolina Colliva, Roberto Pellicciari, Sameh A. Youssef, Alain de Bruin, Yvonne Vercoulen, Folkert Kuipers, Saskia W.C. van Mil
JHEP reports : innovation in hepatology, 2021, vol. 3, p.1-10

Fellowships & Awards

2021: CuCo fellow: strategic alliance consortium Structures of Strength

2020: Member Utrecht Young Academy

2017: Junior member of CancerGenomiCs.nl

2012: Marie Curie International Outgoing Fellowship