Profile photo Wim Otte

Wim Otte

Associate Professor

Strategic program(s):

Biography

Wim Otte is clinical epidemiologist at the UMC Utrecht Brain Center, and specialized in the statistics of predictive modeling research. He advocates open science and Bayesian inference. His recent work is dedicated to epilepsy-related clinical questions with sidesteps in the field of hearing disabilities, meta-research, and philosophy of science.

Strategic program(s):

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Research groups

Personalized prediction, treatment and genetics in epilepsy

Research aim

We develop personalized methods for diagnosing, treating, and predicting outcome in epilepsy. Our aim is to better control seizures, treat comorbidities, and improve quality of life with a precision medicine approach in all people with epilepsy.

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Recent publications

Is the Machine Surpassing Humans? Large Language Models, Structuralism, and Liturgical Ritual: A Position Paper Marcel Barnard, Wim Otte
International Journal of Practical Theology, 2024, vol. 28, p.289-306
Vigabatrin-associated brain magnetic resonance imaging abnormalities and clinical symptoms in infants with tuberous sclerosis complex Carmen Stevering, Maarten Lequin, Kinga Szczepaniak, Krzysztof Sadowski, Saba Ishrat, Alberto De Luca, Alexander Leemans, Willem Otte, David J. Kwiatkowski, Paolo Curatolo, Bernhard Weschke, Kate Riney, Martha Feucht, Pavel Krsek, Rima Nabbout, Anna Jansen, Konrad Wojdan, Kamil Sijko, Jagoda Glowacka-Walas, Julita Borkowska, Dorota Domanska-Pakiela, Romina Moavero, Christoph Hertzberg, Hanna Hulshof, Theresa Scholl, Bořivoj Petrák, Miroslav Maminak, Eleonora Aronica, Jessie De Ridder, Lieven Lagae, Sergiusz Jozwiak, Katarzyna Kotulska, Kees Braun, Floor Jansen
Epilepsia, 2024, vol. 66, p.356-368
Machine learning for (non–)epileptic tissue detection from the intraoperative electrocorticogram Sem Hoogteijling, Eline V. Schaft, Evi H.M. Dirks, Sven Straumann, Matteo Demuru, Pieter van Eijsden, Tineke Gebbink, Willem M. Otte, Geertjan M. Huiskamp, Maryse A. van ’t Klooster, Maeike Zijlmans,
Clinical Neurophysiology, 2024, vol. 167, p.14-25
Quality of life in SCN1A-related seizure disorders across the lifespan. Crista A Minderhoud, Amber Postma, Floor E Jansen, Janneke R Zinkstok, Judith S Verhoeven, Bianca Berghuis, Wim M Otte, Marian J Jongmans, Kees P J Braun, Eva H Brilstra
Brain communications, 2024, vol. 6
Three Prospective Case Studies Examining Mifepristone's Efficacy in Patients with Treatment-Resistant PTSD Agnes van Minnen, Lizelotte Vos, Pierre M Bet, Ad de Jongh, Felix Linsen, Hein J F van Marle, Onno C Meijer, Willem M Otte, Marije Russcher, Christiaan H Vinkers
Case reports in psychiatry, 2024, vol. 2024
Footprint of publication selection bias on meta-analyses in medicine, environmental sciences, psychology, and economics František Bartoš, Maximilian Maier, Eric-Jan Wagenmakers, Franziska Nippold, Hristos Doucouliagos, John P A Ioannidis, Willem M Otte, Martina Sladekova, Teshome K Deresssa, Stephan B Bruns, Daniele Fanelli, T D Stanley
Research Synthesis Methods, 2024, vol. 15, p.500-511

External positions

Dovenpastoraat - Geen, behalve dat door crisispastoraat werktijden mogelijk afgestemd moeten worden - Protestantse Kerk Nederland, Dienstencentrum