Wim Otte

Associate Professor

Strategic program(s):

Biography

Wim Otte is clinical epidemiologist at the UMC Utrecht Brain Center, and specialized in the statistics of predictive modeling research. He advocates open science and Bayesian inference. His recent work is dedicated to epilepsy-related clinical questions with sidesteps in the field of hearing disabilities, meta-research, and philosophy of science.

Strategic program(s):

Contact

wotte@umcutrecht.nl

Pure profile

Research groups

Personalized prediction, treatment and genetics in epilepsy

Research aim

We develop personalized methods for diagnosing, treating, and predicting outcome in epilepsy. Our aim is to better control seizures, treat comorbidities, and improve quality of life with a precision medicine approach in all people with epilepsy.

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Recent publications

All publications

Timing for Starting Antiseizure Medication Withdrawal After Epilepsy Surgery in Adults Carolina Ferreira-Atuesta, Jane De Tisi, Andrew William Mcevoy, Anna Miserocchi, Jean Khoury, Ruta Yardi, Deborah Vegh, James Thomas Butler, Hamin John Lee, Victoria Ives-Deliperi, Yi Yao, Feng Peng Wang, Xiaobin Zhang, Lubna Shakhatreh, Pakeeran Siriratnam, Andrew Neal, Arjune Sen, Maggie Tristram, Bernard Liem, Elizabeth Neethu Varghese, Wendy Beatrice Biney, William P. Gray, Catarina Correia Rodrigues, Ana Rita Peralta, Alexandre Rainha Campos, António Jdc Goncalves-Ferreira, José Pimentel, Vít Všianský, Juan Fernando Arias, Mohsen Farazdaghi, Robert Terziev, Krishna Ranjith Kadali, Kristina Koenig, Marcellina Haeberlin, Willem M. Otte, Fergus Rugg-Gunn, Samuel W. Terman, Kees P.J. Braun, Lukas L. Imbach, Ali A. Asadi-Pooya, Walter Gonzalez-Salazar, Martin Pail, Carla C. Bentes, Khalid Hamandi, Terence J. O'Brien, Piero Perucca, Chen Yao, Richard J. Burman, Lara E. Jehi, John S. Duncan, Josemir W. Sander, Matthias Koepp, Marian Galovic
Neurology, 2026, vol. 106, p.e214613

Reliability and state-dependency of EEG connectivity, complexity and network characteristics L. S. Dominicus, D. Y. Lodema, B. Oranje, M. G. Zandstra, A. P.C. Hermans, L. Imhof, W. M. Otte, A. Hillebrand, K. Ambrosen, C. J. Stam, B. H. Ebdrup, E. van Dellen
Scientific Reports, 2025, vol. 15

The use of IPD meta-analysis in maternal health prognostics Willem M Otte
Lancet (London, England), 2025, vol. 406, p.1926-1927

What determines the timing of epilepsy surgery in children with cortical malformations and low-grade epilepsy-associated tumors? Maurits W.C.B. Sanders, Matyas Ebel, Aswin Chari, Merel Fleumer, Anca M. Vasilica, Maria H. Eriksson, Martin Tisdall, Barbora Splitkova, Anezka Belohlavkova, Willem M. Otte, Floor E. Jansen, J. Helen Cross, Kees P.J. Braun, Pavel Krsek
Epilepsia Open, 2025, vol. 10, p.1345-1352

Antiseizure medication reduction in long-term video-electroencephalographic monitoring for presurgical evaluation Renate van Griethuysen, Charlotte J J van Asch, Willem M Otte, Herm Lamberink, Josemir W Sander, Mireille D Bourez-Swart, Lotte de Jong, Albert J Colon, Kees P J Braun,
Epilepsia, 2025, vol. 66, p.4490-4500

Structural and effective brain connectivity in focal epilepsy S. B. Jelsma, M. Zijlmans, I. B. Heijink, F. W.A. Hoefnagels, M. Raemaekers, W. M. Otte, N. E.C. van Klink, D. van Blooijs
Neuroimage: Reports, 2025, vol. 5

External positions

Dovenpastoraat - Geen, behalve dat door crisispastoraat werktijden mogelijk afgestemd moeten worden - Protestantse Kerk Nederland, Dienstencentrum