Wim Otte

Associate Professor

Strategic program(s):

Biography

Wim Otte is clinical epidemiologist at the UMC Utrecht Brain Center, and specialized in the statistics of predictive modeling research. He advocates open science and Bayesian inference. His recent work is dedicated to epilepsy-related clinical questions with sidesteps in the field of hearing disabilities, meta-research, and philosophy of science.

Strategic program(s):

Contact

wotte@umcutrecht.nl

Pure profile

Research groups

Personalized prediction, treatment and genetics in epilepsy

Research aim

We develop personalized methods for diagnosing, treating, and predicting outcome in epilepsy. Our aim is to better control seizures, treat comorbidities, and improve quality of life with a precision medicine approach in all people with epilepsy.

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Recent publications

All publications

Structural and effective brain connectivity in focal epilepsy S. B. Jelsma, M. Zijlmans, I. B. Heijink, F. W.A. Hoefnagels, M. Raemaekers, W. M. Otte, N. E.C. van Klink, D. van Blooijs
Neuroimage: Reports, 2025, vol. 5

Blueprint for clinical N-of-1 strategies with off-label precision treatments in monogenic epilepsies Victoria M Defelippe, Eva H Brilstra, Willem M Otte, Ghislaine J M W van Thiel, Helen J Cross, Finbar O'Callaghan, Valentina De Giorgis, Emilio Perucca, Kees P J Braun, Floor E Jansen
Orphanet Journal of Rare Diseases, 2025, vol. 20

Comparison of children and adults undergoing subdural grid electrode implantation or stereoelectroencephalography in a refractory epilepsy cohort from four European centers Matea Rados, Shanice Beerepoot, Martin M Tisdall, Ronit M Pressler, J Helen Cross, Rachel C Thornton, Beate Diehl, Andrew W McEvoy, Anna Miserocchi, Josemir W Sander, John S Duncan, Jane de Tisi, Francesco Cardinale, Laura Tassi, Giorgio Lo Russo, Stefano Francione, Herm J Lamberink, Frans S S Leijten, Willem M Otte, Sandra M A van der Salm, Kees P J Braun, Pieter van Eijsden
Epilepsia, 2025, vol. 66, p.2715-2727

Anti-seizure medication is a minor causative factor in behavioral problems of children with tuberous sclerosis complex H. M. Hulshof, J. K. Heijstek, W. M. Otte, H. Bruining, K. P.J. Braun, F. E. Jansen
Epilepsy and Behavior, 2025, vol. 168

Exploring determinants of time to school re-entry after pediatric epilepsy surgery Evangeline A. Huis in 't Veld, Olga Braams, Willem M. Otte, Peter van Rijen, Kees P.J. Braun, Renske Schappin
Epilepsy and Behavior Reports, 2025, vol. 30

Determinants of intellectual and developmental outcomes in a multicenter pediatric hemispherotomy cohort Georgia Ramantani, Dorottya Cserpan, Martin Tisdall, Willem M Otte, Georg Dorfmüller, Isabelle Jambaqué, J Helen Cross, Monique van Schooneveld, Pieter van Eijsden, Gitta Reuner, Niklaus Krayenbühl, Sarah Ferrand-Sorbets, Josef Zentner, Kees P J Braun, Christine Bulteau
Epilepsia, 2025, vol. 66, p.2213-2224

External positions

Dovenpastoraat - Geen, behalve dat door crisispastoraat werktijden mogelijk afgestemd moeten worden - Protestantse Kerk Nederland, Dienstencentrum