Profile photo Wilton van Klei

Wilton van Klei

Full Professor

Strategic program(s):

Biography

Wilton van Klei received his PhD in 2002 and completed his postgraduate training as anesthesiologist in the Netherlands (2006. After that he did a clinical and research fellowship in perioperative medicine (Ottawa, Ontario, 2007). He returned to the Netherlands to complete a fellowship in cardiothoracic anesthesia (2009), including training in TEE. From 2007 till 2012, he was the Medical Director of the Outpatient Preoperative Evaluation Clinic of the UMC Utrecht. Subsequently, he was the Chair of the Department of Anesthesiology and the Director Research and Education of the Division of Anesthesiology, Intensive Care and Emergency Medicine of the UMC Utrecht (2013-2021). Curently, his primary affiliation is at the University Health Network Toronto / University of Toronto, but he holds a small appointment as a research professor at the UMC Utrecht.

 

His interests focus on improving care for high-risk surgical patients, and involve collaborations with cardiologists, surgeons, clinical chemists, and epidemiologists within the UMC Utrecht’s Circulatory Health research programme. He is supervising several PhD students on clinical research projects in the field of cardiovascular perioperative medicine. Most projects aim to unravel further the etiology, detection and treatment of asymptomatic myocardial injury after surgery. He considers hisself a specialist in perioperative medicine.
Perioperative medicine starts before surgery with a preanesthesia assessment and currently often ends with the patient leaving the recovery room, except for a responsibility for postoperative pain management. However, anesthesiologists should be involved not only in pain management, but also in providing postoperative care on general wards, monitoring vital functions and monitoring for complications likely to be related to surgery and anesthesia. In fact, anesthesiologists should extend what they are doing in the operating room to the surgical floor in order to improve patient outcomes. He is working towards this goal by initiating research in those areas where evidence for optimal treatment is absent.

Research groups

Perioperative risk management and monitoring

Research aim

Our research aim is to improve prevention and early detection of complications in surgical patients, in order to reduce morbidity and improve or preserve quality of life, and to develop novel monitoring techniques and advanced AI technology.

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Recent publications

Peri-operative corticosteroid supplementation guideline adherence Lynn A. Miggelbrink, Marije Marsman, Juul van de Wetering, Wilton A. van Klei, Teus H. Kappen
Anaesthesia, 2025, vol. 80, p.454-455
Variability in Intraoperative Opioid and Nonopioid Utilization During Intracranial Surgery Bhiken I. Naik, Abhijit V. Lele, Deepak Sharma, Annemarie Akkermans, Phillip E. Vlisides, Douglas A. Colquhoun, Karen B. Domino, Siny Tsang, Eric Sun, Lauren K. Dunn, Michael R. Mathis, Nathan L. Pace, David J. Clark, Patrick J. McCormick, Wilton van Klei, Marie A. Theard,
Journal of Neurosurgical Anesthesiology, 2025, vol. 37, p.70-74
Postoperative myocardial injury phenotypes and self-reported disability in patients undergoing noncardiac surgery Lisette M. Vernooij, Judith A.R. van Waes, Remco B. Grobben, Felix van Lier, Simon Feng, Matthew Machina, Michael McKenny, Hendrik M. Nathoe, Duminda N. Wijeysundera, Wilton A. van Klei, W. Scott Beattie
British Journal of Anaesthesia, 2024
Shedding Needed Light on a Black Box Approach to Prediction of Hypotension Simon T. Vistisen, Martin J. London, Michael R. Mathis, Wilton A. van Klei, Snehalata Huzurbazar, Matthias Jacquet-Lagrèze
Anesthesiology, 2024, vol. 141, p.421-424
Postoperative myocardial injury phenotypes and self-reported disability in patients undergoing noncardiac surgery Lisette M. Vernooij, Judith A.R. van Waes, W. Scott Beattie, Wilton A. van Klei
British Journal of Anaesthesia, 2024, vol. 133, p.696-697
Association of Intraoperative Hypotension With Delayed Graft Function Following Kidney Transplant Marc Sicova, Ryan McGinn, Sophia Emerson, Paula Perez, Roberto Gonzalez, Yanhong Li, Olusegum Famure, Ian Randall, Daniel Santa Mina, Michael Santema, Duminda N. Wijeysundera, Wilton Van Klei, S. Joseph Kim, Stuart A. McCluskey
Clinical transplantation, 2024, vol. 38

Fellowships & Awards

2011 Research Award of the International Anesthesia Research Society (IARS)