Profile photo Paco Welsing

Paco Welsing

Associate Professor

Biography

I am a clinical Epidemiologist and HTA researcher. My research focuses on the optimal application of health interventions in daily clinical practice with a focus on rheumatic and immunologic diseases, mainly Rheumatoid Arthritis (RA) and Osteoarthritis (OA). More stratified approaches to treatment and the measurement of these treatment effects have been studied in different project, acting as project member/methodologist or (WP) lead. Examples are the CTMM TRACER project focussing on the clinical and health-economic evaluation of personalized approached to diagnosis and treatment of RA, the IMI APPROACH project focussing on exploring phenotypes of osteoarthritis for stratified treatment approaches, the IMI GetReal project focusing on the use of ‘Real World’ data in drug evaluation, specifically focussing on pragmatic trial design and using data from routine practice in trials, the multicenter PATIO trial evaluating a prediction based decision aid tool for tapering biological drugs in RA, the nationwide RCT and cohort study, GODIVA, regarding the (cost-)effectiveness and optimal patient group for joint distraction in young patients with severe knee OA and the EU STRATA-FIT project focussing on difficult-to-treat RA and the development of a stratified treatment approach and decision aid using real world. As the full effects of a treatment strategy when applied in clinical practice are of interest my research naturally includes modelling the clinical effectiveness as well as cost-effectiveness on the long term. I enjoy applying/adapting state-of the art statistical and Machine Learning methods in an innovative and creative way to clinical research questions also working as a methodologist consultant for our division.

Research groups

Rheumatology & clinical immunology

Research aim

To improve clinical practice by optimizing diagnosis, prognosis and treatment of rheumatic and immune-mediated and immune-deficient inflammatory diseases

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Knee joint preserving treatments

Research aim

The main goal of our research group is to develop and test joint preserving treatments for the knee joint, for pathology ranging from cartilage lesions to endstage osteoarthritis

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Recent publications

Design of TOLERANT Arie Jan Stoppelenburg, Gerty Schreibelt, Bouke Koeneman, Paco Welsing, Evert-Jan Breman, Laureen Lammers, Anna de Goede, Tjitske Duiveman-de Boer, Willem van Eden, Paul Leufkens, I Jolanda M de Vries, Femke Broere, Jacob M van Laar
BMJ Open, 2024, vol. 14
House dust mite sublingual allergen immunotherapy tablet is safe and well-tolerated in Dutch clinical practice Žana Tempels-Pavlica, Mark C J Aarts, Paco M J Welsing, Akke-Nynke van der Meer, Leonard P van der Zwan, Elena Uss, André C Knulst
Frontiers in allergy, 2024, vol. 5
Prognostication of progressive pulmonary fibrosis in connective tissue disease-associated interstitial lung diseases Yu Hsiang Chiu, Maaike F.M. Koops, Mareye Voortman, H. Wouter van Es, Lucianne C.M. Langezaal, Paco M.J. Welsing, Anna Jamnitski, Anne E. Wind, Jacob M. van Laar, Jan C. Grutters, Julia Spierings
Frontiers in medicine, 2023, vol. 10
Exploring the differences between radiographic joint space width and MRI cartilage thickness changes using data from the IMI-APPROACH cohort Mylène P. Jansen, Frank W. Roemer, Anne Karien C.A. Marijnissen, Margreet Kloppenburg, Francisco J. Blanco, Ida K. Haugen, Francis Berenbaum, Floris P.J.G. Lafeber, Paco M.J. Welsing, Simon C. Mastbergen, Wolfgang Wirth
Skeletal Radiology, 2023, vol. 52, p.1339-1348
Component Ana o 3 versus extract for cashew nut allergy Emily J.J. Kallen, Juliette F. Bollemeijer, André C. Knulst, Anna M. Ehlers, Paco M.J. Welsing, Ronald van Ree, Thuy My Le
Clinical and Experimental Allergy, 2023, vol. 53, p.880-882
Points to consider for cost-effective use of biological and targeted synthetic DMARDs in inflammatory rheumatic diseases Céleste J.T. Van Der Togt, Bart Van Den Bemt, Daniel Aletaha, Rieke Alten, Katerina Chatzidionysiou, James Galloway, John Isaac, Denis Mulleman, P. Verschueren, Arnold G. Vulto, Paco M.J. Welsing, Lise Verhoef, Alfons A. Den Broeder
RMD Open, 2023, vol. 9