Profile photo Frank Visseren

Frank Visseren

Full Professor

Strategic program(s):

Biography

Frank Visseren (1965) is Internist, Epidemiologist and Professor in Vascular Medicine at the University Medical Center in Utrecht. He is head of the Department of Vascular Medicine and responsible for patient care, research, and teaching. The Department of Vascular Medicine at the UMC Utrecht consists of Internists, Fellows, Research Nurses and PhD students. His main research interest is in the field of insulin resistance and vascular diseases and consists of basic, translational and epidemiologic research covering etiology, therapy, prognosis and diagnosis. There is a focus on (visceral) adipose tissue and development of atherosclerosis, atherotrombosis and diabetes. An other research focus is on translating the results of large clinical trials to invidivual patients, in collaboration with (inter)national partners. He is (co-)author of over 300 publications and associate editor of 2 scientific journals. The GCP certified research unit of the Department of Vascular Medicine performs state-of-the-art non-invasive vascular imaging tests including FMD, FBF, PWV, fingertip plethysmography, IMT and HRV. There is broad experience with industry-sponsored clinical trials in the field of Vascular Medicine, Cardiology and Diabetology and he also serves as sponsor of multi-national investigator initiated studies. He is the clinical director of the Second Manifestations of ARTerial disease (SMART) cohort at the UMC Utrecht. This is a cohort with over 13,000 patients with vascular diseases and/or type 2 diabetes or severe hypertension or familial hyperlipidemia, growing with 800 patients annually, for etiologic, prognostic, diagnostic and therapeutic research. He was (co-)supervisor of 30 thesis and currently involved in the supervision of 11  PhD students.

The clinical work of the Department of Vascular Medicine is concentrated around patients at high risk for the development of cardiovascular diseases including patients with Familial Hypercholesterolemia, patients with therapy-resistant hypertension and patients with diabetes and vascular disease. He strongly believes in a multidisciplinary, patient-centered approach in the treatment of patients at high risk for the development of (new) vascular diseases.

Teaching covers first year Medical Students to clinical specialty training in Vascular Medicine. He is member of the Concilium Medicinae Internae and chairman of the section Vascular Medicine of the Dutch Internal Medicine Society.

Recent publications

Association between lower extremity arterial calcification and coronary arterial calcification in a population at increased risk of cardiovascular disease Romain Meer, Anna G. Hoek, Emma J. Bouman, Teddo Doesburg, Petra J.M. Elders, P. A. de Jong, Joline Beulens, M. J. Cramer, H. M. Nathoe, M. G. van der Meer, G. J. de Borst, M. Teraa, M. L. Bots, M. van Smeden, M. H. Emmelot-Vonk, P. A. de Jong, A. T. Lely, N. P. van der Kaaij, L. J. Kappelle, Y. M. Ruigrok, M. C. Verhaar, J. A.N. Dorresteijn, F. L.J. Visseren,
BMJ Open Diabetes Research and Care, 2024, vol. 12
Plasma lipids in Pseudoxanthoma Elasticum (PXE) patients Iris M Harmsen, Frank L J Visseren, Madeleine Kok, Pim A de Jong, Wilko Spiering
Atherosclerosis Plus, 2024, vol. 55, p.5-11
Effect of dietary patterns on cardiovascular risk factors in people with type 2 diabetes. A systematic review and network meta-analysis N. E. Bonekamp, I. van Damme, J. M. Geleijnse, R. M. Winkels, F. L.J. Visseren, P. B. Morris, C. Koopal
Diabetes Research and Clinical Practice, 2023, vol. 195
Variability in benefit from intensive insulin therapy on cardiovascular events in individuals with type 1 diabetes Marga A.G. Helmink, Steven H.J. Hageman, Frank L.J. Visseren, Wendela L. de Ranitz-Greven, Harold W. de Valk, Thomas T. van Sloten, Jan Westerink
Diabetic Medicine, 2023, vol. 40, p.1-10
Effect of adipose tissue quantity and dysfunction on the risk of cancer in individuals with and without type 2 diabetes Marga A.G. Helmink, Jan Westerink, Steven H.J. Hageman, Miriam Koopman, Manon G. van der Meer, Martin Teraa, Ynte M. Ruigrok, Frank L.J. Visseren
Obesity Research and Clinical Practice, 2023, vol. 17, p.383-389
Temporal Trends and Determinants of Stroke Risk in Patients With Medically Treated Asymptomatic Carotid Stenosis Michiel H F Poorthuis, Yoel Solomon, Reinier A R Herings, Frank L J Visseren, L Jaap Kappelle, Michiel L Bots, Ina Rissanen, Gert J de Borst
Stroke, 2023, vol. 54, p.1735-1749