Alexander van Oudenaarden

Full Professor

Strategic program(s):

Contact

a.vanoudenaarden@hubrecht.eu

Pure profile

Recent publications

All publications

Effects of Neurogenin 3 Induction on Endocrine Differentiation and Delamination in Adult Human Pancreatic Ductal Organoids Juri Juksar, Rachel Mijdam, Sabine Bosman, Alexander van Oudenaarden, Françoise Carlotti, Eelco J.P. de Koning
Transplant International, 2025, vol. 38

An engineered tumor organoid model reveals cellular identity and signaling trajectories underlying SFPQ-TFE3 driven translocation RCC Maroussia M.P. Ganpat, Francisco Morales-Rodriguez, Nhung Pham, Philip Lijnzaad, Terezinha de Souza, Sepide Derakhshan, Arianna Fumagalli, Peter Zeller, Aleksandra Balwierz, Dilara Ayyildiz, Marry M. van den Heuvel-Eibrink, Ronald R. de Krijger, Alexander van Oudenaarden, Thanasis Margaritis, Susana M. Chuva de Sousa Lopes, Jarno Drost
iScience, 2025, vol. 28

Long-term in vitro expansion of a human fetal pancreas stem cell that generates all three pancreatic cell lineages Amanda Andersson-Rolf, Kelvin Groot, Jeroen Korving, Harry Begthel, Maaike A.J. Hanegraaf, Michael VanInsberghe, Fredrik Salmén, Stieneke van den Brink, Carmen Lopez-Iglesias, Peter J. Peters, Daniel Krueger, Joep Beumer, Maarten H. Geurts, Anna Alemany, Helmuth Gehart, Françoise Carlotti, Eelco J.P. de Koning, Susana M. Chuva de Sousa Lopes, Alexander van Oudenaarden, Johan H. van Es, Hans Clevers
Cell, 2024, vol. 187, p.7394-7413.e22

Developmental signals control chromosome segregation fidelity during pluripotency and neurogenesis by modulating replicative stress Anchel de Jaime-Soguero, Janina Hattemer, Anja Bufe, Alexander Haas, Jeroen van den Berg, Vincent van Batenburg, Biswajit Das, Barbara di Marco, Stefania Androulaki, Nicolas Böhly, Jonathan J.M. Landry, Brigitte Schoell, Viviane S. Rosa, Laura Villacorta, Yagmur Baskan, Marleen Trapp, Vladimir Benes, Andrei Chabes, Marta Shahbazi, Anna Jauch, Ulrike Engel, Annarita Patrizi, Rocio Sotillo, Alexander van Oudenaarden, Josephine Bageritz, Julieta Alfonso, Holger Bastians, Sergio P. Acebrón
Nature Communications, 2024, vol. 15

Paradoxical Activation of Oncogenic Signaling as a Cancer Treatment Strategy Matheus Henrique Dias, Anoek Friskes, Siying Wang, Joao M. Fernandes Neto, Frank van Gemert, Soufiane Mourragui, Chrysa Papagianni, Hendrik J. Kuiken, Sara Mainardi, Daniel Alvarez-Villanueva, Cor Lieftink, Ben Morris, Anna Dekker, Emma van Dijk, Lieke H.S. Wilms, Marcelo S. da Silva, Robin A. Jansen, Antonio Mulero-Sánchez, Elke Malzer, August Vidal, Cristina Santos, Ramón Salazar, Rosangela A.M. Wailemann, Thompson E.P. Torres, Giulia De Conti, Jonne A. Raaijmakers, Petur Snaebjornsson, Shengxian Yuan, Wenxin Qin, John S. Kovach, Hugo A. Armelin, Hein Te Riele, Alexander van Oudenaarden, Haojie Jin, Roderick L. Beijersbergen, Alberto Villanueva, Rene H. Medema, Rene Bernards
Cancer Discovery, 2024, vol. 14, p.1276-1301

Quantifying DNA replication speeds in single cells by scEdU-seq Jeroen van den Berg, Vincent van Batenburg, Christoph Geisenberger, Rinskje B. Tjeerdsma, Anchel de Jaime-Soguero, Sergio P. Acebrón, Marcel A.T.M. van Vugt, Alexander van Oudenaarden
Nature Methods, 2024, vol. 21, p.1175-1184