Profile photo Tristan van Doormaal

Tristan van Doormaal

Associate Professor - medical

Strategic program(s):

Biography

My research focusses on the bench to bedside development of devices that improve outcome of patients with a neurosurgical disease. 

I started my research carreer as a PhD in the group of Prof CAF Tulleken and Prof A van der Zwan at the UMC Utrecht, and I co-invented several ways to make a bypass in the brain. These techniques were ultimately used to treat patients.

After my PhD, during my neurosurgical trianing, I invented and co-developed a new sealant (in the media it is referred to as 'plaster') to prevent cerebrospinal fluid leakage after brain surgery.  I did all developents under public private flag together with Polyganics BV, and the intellectual property (IP) was transferred from UMC Utrecht to this company to make the technique available for patients. The device (formally called 'Liqoseal') is now standard of care in Europe and under research in the USA.

A few years ago I started to do research with Augmented Reality to inform patients, train residents and provide active guidance during brain surgery. The IP I developed was tranferred to a UMC Utrecht spinoff called 'Augmedit'. I combine my function as a neurosurgeon, nowadays both in the UMC Utrecht and the University Medical Center in Zurich, Switserland, with being Chief Medical Officer of this company. My research group in the UMCU works closely together with Augmedit, the Prinsess Maxima Center and University Medical Center Zurich to design optimal software to inform patients, train residents and to ultimately prevent complications during brainsurgery. 

Research groups

Intracranial vasculopathies

Research aim

Our research focusses on the diagnosis, treatment, and prevention of stroke and intracranial vasculopathies, including cerebral small vessel disease and intracranial aneurysms, with the ultimate goal to improve treatment strategies and prognosis.

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Recent publications

Clinical Application and Further Development of Augmented Reality Guidance for the Surgical Localization of Pediatric Chest Wall Tumors Rémi van der Woude, Matthijs Fitski, Jasper M. van der Zee, Cornelis P. van de Ven, Guus M.J. Bökkerink, Marc H.W.A. Wijnen, Jene W. Meulstee, Tristan P.C. van Doormaal, Françoise J. Siepel, Alida F.W. van der Steeg
Journal of Pediatric Surgery, 2024, vol. 59, p.1549-1555
Evaluation Metrics for Augmented Reality in Neurosurgical Preoperative Planning, Surgical Navigation, and Surgical Treatment Guidance Tessa M Kos, Elisa Colombo, L Wilbert Bartels, Pierre A Robe, Tristan P C van Doormaal
Operative Neurosurgery, 2023, vol. 26, p.491-501
Incisional CSF leakage after intradural cranial surgery in children Emma M.H. Slot, Tristan P.C. van Doormaal, Kirsten M. van Baarsen, Niklaus Krayenbühl, Luca Regli, Menno R. Germans, Eelco W. Hoving
Journal of Neurosurgery: Pediatrics, 2023, vol. 31, p.313-320
Mixed Reality in Modern Surgical and Interventional Practice Mats T Vervoorn, Maaike Wulfse, Tristan P C Van Doormaal, Jelle P Ruurda, Niels P Van der Kaaij, Linda M De Heer
JMIR Serious Games, 2023, vol. 11, p.e41297
NnU-Net versus mesh growing algorithm as a tool for the robust and timely segmentation of neurosurgical 3D images in contrast-enhanced T1 MRI scans Mathijs de Boer, Tessa Kos, Tim Fick, Jesse van Doormaal, Elisa Colombo, Hugo Kuijf, PAJT Robe, L.P.E. Regli, Lambertus Bartels, TPC van Doormaal
Acta Neurochirurgica, 2023, vol. 166
Case report Elisa Colombo, Delal Bektas, Luca Regli, Tristan van Doormaal
Frontiers in surgery, 2023, vol. 10

External positions

Neurosurgeon, University of Zurich

Chief Medical Officer, Augmedit