Profile photo Tolboom

Tolboom

Assistant Professor - medical

Strategic program(s):

Biography

Nuclear medicine physician,
Department of Radiology and Nuclear Medicine, University Medical Centre Utrecht and Princess Maxima Centre for pediatric oncology, Utrecht (fixed term).

Specific clinical fields of interest:
Nuclear Neuro-imaging (i.e. neuro-oncology, epilepsy, neurodegeneration), Pediatric nuclear imaging, Hemato-oncology, Head and Neck oncology, Nuclear therapies (theranostics)

Research line: 
Clinical neuro imaging (co-PI of multicenter study using FET PET for management of glioblastoma, local PI of multicenter TAU PET study investigating clinical value of TAU PET in neurodegeneration), national PI for an European Organization for Research and Treatment of Cancer (EORTC) initiated nuclear treatment study in Meningioma (‘LUMEN’ study). Experimental neuroimaging using neuroinflammation tracers (PI of multi-center study using neuroinflammation PET).

Leadership:
-Member and vice chair of EORTC Brain tumour group/ nuclear medicine committee.
-Member of Neuroimaging committee, European Association of Nuclear Medicine (EANM)
-EANM representative for the European Academy of Neurology (EAN), member of management group of EAN scientific panel on neuroimaging.
-EANM liaison person to the EAN Brain Health Summit initiative.
-Co-Chair of Dutch Society for Nuclear Medicine Neuroimaging committee.

Research groups

Nuclear theranostics research

Research aim

With nuclear theranostics we aim to develop radiopharmaceuticals to improve the disease diagnosis and therapy, including clinical translation for direct impact. Disease areas of interest are (childhood) cancer, neurology and infectious diseases.

Go to group

Clinical and translational neuro-oncology

Research aim

We aim to improve treatments and clinical outcomes of patients with gliomas and other brain tumors, by combining expertise from oncobiology, neuropsychology, imaging, surgical & clinical neurology, and palliative care.

Go to group

Recent publications

Multimodality imaging of bone marrow involvement in paediatric oncology Rutger A.J. Nievelstein, Lise Borgwardt, Thekla von Kalle, Annemieke S. Littooij, Lil Sofie Ording Müller, Nelleke Tolboom
EJC Paediatric Oncology, 2024, vol. 4
EANM perspectives for CZT SPECT in brain applications Antoine Verger, Diego Cecchin, Eric Guedj, Nathalie L Albert, Matthias Brendel, Francesco Fraioli, Nelleke Tolboom, Tatjana Traub-Weidinger, Igor Yakushev, Donatienne Van Weehaeghe, Pablo Aguiar Fernandez, Valentina Garibotto, Laetitia Imbert
European Journal of Nuclear Medicine and Molecular Imaging, 2024, vol. 51, p.3680-3684
Joint EANM/EANO/RANO/SNMMI practice guideline/procedure standards for diagnostics and therapy (theranostics) of meningiomas using radiolabeled somatostatin receptor ligands Nathalie L Albert, Matthias Preusser, Tatjana Traub-Weidinger, Nelleke Tolboom, Ian Law, Joshua D Palmer, Eric Guedj, Julia Furtner, Francesco Fraioli, Raymond Y Huang, Derek R Johnson, Christophe M Deroose, Ken Herrmann, Michael Vogelbaum, Susan Chang, Joerg-Christian Tonn, Michael Weller, Patrick Y Wen, Martin J van den Bent, Antoine Verger, Jana Ivanidze, Norbert Galldiks
European Journal of Nuclear Medicine and Molecular Imaging, 2024, vol. 51, p.3662-3679
Neuroimaging biomarkers in the biological definition of Parkinson's disease and dementia with Lewy bodies - EANM position on current state, unmet needs and future perspectives Matthias Brendel, Eric Guedj, Igor Yakushev, Silvia Morbelli, Günter U Höglinger, Nelleke Tolboom, Antoine Verger, Nathalie L Albert, Diego Cecchin, Pablo Aguiar Fernandez, Francesco Fraioli, Tatjana Traub-Weidinger, Donatienne Van Weehaeghe, Henryk Barthel
European Journal of Nuclear Medicine and Molecular Imaging, 2024, vol. 51, p.3496-3500
Translating the theranostic concept to neuro-oncology Nathalie L. Albert, Emilie Le Rhun, Giuseppe Minniti, Maximilian J. Mair, Norbert Galldiks, Nelleke Tolboom, Asgeir S. Jakola, Maximilian Niyazi, Marion Smits, Antoine Verger, Francesco Cicone, Michael Weller, Matthias Preusser,
The Lancet Oncology, 2024, vol. 25, p.e441-e451
Potential of non-FDG PET radiotracers for paediatric patients with solid tumours Leonor Teles, Nelleke Tolboom, Sabine L.A. Plasschaert, Alex J. Poot, Arthur J.A.T. Braat, Max M. van Noesel
EJC Paediatric Oncology, 2024, vol. 4