Profile photo Tolboom

Tolboom

Assistant Professor - medical

Strategic program(s):

Biography

Nuclear medicine physician,
Department of Radiology and Nuclear Medicine, University Medical Centre Utrecht and Princess Maxima Centre for pediatric oncology, Utrecht (fixed term).

Specific clinical fields of interest:
Nuclear Neuro-imaging (i.e. neuro-oncology, epilepsy, neurodegeneration), Pediatric nuclear imaging, Hemato-oncology, Head and Neck oncology, Nuclear therapies (theranostics)

Research line: 
Clinical neuro imaging (co-PI of multicenter study using FET PET for management of glioblastoma, local PI of multicenter TAU PET study investigating clinical value of TAU PET in neurodegeneration), national PI for an European Organization for Research and Treatment of Cancer (EORTC) initiated nuclear treatment study in Meningioma (‘LUMEN’ study). Experimental neuroimaging using neuroinflammation tracers (PI of multi-center study using neuroinflammation PET).

Leadership:
-Member and vice chair of EORTC Brain tumour group/ nuclear medicine committee.
-Member of Neuroimaging committee, European Association of Nuclear Medicine (EANM)
-EANM representative for the European Academy of Neurology (EAN), member of management group of EAN scientific panel on neuroimaging.
-EANM liaison person to the EAN Brain Health Summit initiative.
-Co-Chair of Dutch Society for Nuclear Medicine Neuroimaging committee.

Research groups

Nuclear theranostics research

Research aim

With nuclear theranostics we aim to develop radiopharmaceuticals to improve the disease diagnosis and therapy, including clinical translation for direct impact. Disease areas of interest are (childhood) cancer, neurology and infectious diseases.

Go to group

Clinical and translational neuro-oncology

Research aim

We aim to improve treatments and clinical outcomes of patients with gliomas and other brain tumors, by combining expertise from oncobiology, neuropsychology, imaging, surgical & clinical neurology, and palliative care.

Go to group

Recent publications

Comparison of 18F-FET-PET- and MRI-based target definition for re-irradiation treatment of recurrent diffuse glioma Albert Everard, Daniel Versnel, Veerle Ruijters, Nelleke Tolboom, Marielle Philippens, Tom Snijders, Joost Verhoeff, Szabolcs David, Casper Beijst
Clinical and translational radiation oncology, 2025, vol. 52
Lecanemab approval in EU Igor Yakushev, Antoine Verger, Matthias Brendel, Diego Cecchin, Pablo Aguiar Fernandez, Francesco Fraioli, Timo Grimmer, Nelleke Tolboom, Tatjana Traub-Weidinger, Eric Guedj, Donatienne Van Weehaeghe
European Journal of Nuclear Medicine and Molecular Imaging, 2025, vol. 52, p.1607-1610
Joint EANM/EANO/RANO/SNMMI practice guideline/procedure standard for PET imaging of brain metastases Antoine Verger, Nelleke Tolboom, Francesco Cicone, Susan M. Chang, Julia Furtner, Norbert Galldiks, Jens Gempt, Eric Guedj, Raymond Y. Huang, Derek R. Johnson, Ian Law, Emilie Le Rhun, Susan C. Short, M. J.Van den Bent, Donatienne Van Weehaeghe, Michael A. Vogelbaum, Patrick Y. Wen, Nathalie L. Albert, Matthias Preusser
European Journal of Nuclear Medicine and Molecular Imaging, 2025, vol. 52, p.1822-1839
Potential of non-FDG PET radiotracers for paediatric patients with solid tumours Leonor Teles, Nelleke Tolboom, Sabine L.A. Plasschaert, Alex J. Poot, Arthur J.A.T. Braat, Max M. van Noesel
EJC Paediatric Oncology, 2024, vol. 4
The impact of tau-PET in a selected memory clinic cohort Marie R. Vermeiren, Joost Somsen, Gert Luurtsema, Fransje E. Reesink, Nicolaas A. Verwey, Liesbeth Hempenius, Nelleke Tolboom, Geert Jan Biessels, J. Matthijs Biesbroek, Meike W. Vernooij, Sophie E.M. Veldhuijzen van Zanten, Harro Seelaar, Emma M. Coomans, Charlotte E. Teunissen, Afina W. Lemstra, Argonde C. van Harten, Leonie N.C. Visser, Wiesje M. van der Flier, Elsmarieke van de Giessen, Rik Ossenkoppele
Alzheimer's Research & Therapy, 2024, vol. 16
Translating the theranostic concept to neuro-oncology Nathalie L. Albert, Emilie Le Rhun, Giuseppe Minniti, Maximilian J. Mair, Norbert Galldiks, Nelleke Tolboom, Asgeir S. Jakola, Maximilian Niyazi, Marion Smits, Antoine Verger, Francesco Cicone, Michael Weller, Matthias Preusser,
The Lancet Oncology, 2024, vol. 25, p.e441-e451