Profile photo Thomas van Sloten

Thomas van Sloten

Assistant Professor - medical

Strategic program(s):

Biography

Dr Thomas van Sloten works as an clinical-scientist (Assistant Professor) at the Department of Vascular Medicine of University Medical Centre Utrecht, the Netherlands. He studied Medicine at Maastricht University and Clinical Epidemiology at VU University Amsterdam, both in the Netherlands. He did his PhD research at the Department of Internal Medicine of Maastricht University Medical Centre, Maastricht, the Netherlands. Thomas also worked at the National Institutes of Health (USA) and at INSERM U970, Paris Cardiovascular Research Center (France). 

The focus of his research is the epidemiological study of the role of vascular dysfunction in the development brain diseases that are common among individuals with diabetes, including stroke, dementia and depression. A key element of his research is that he combines multiple research domains, including epidemiology, endocrinology, physiology, neuropsychiatry and neuroimaging science. He has also always combined research with clinical work. Thomas has been awarded with various grants, including a Veni grant (Dutch Research Council NWO talent scheme), a Dekker clinical scientist grant (Dutch Heart Foundation) and a Diabetes Fonds Fellowship (Dutch Diabetes Research Foundation). His scientific work has been published in leading journals in the field, such as Lancet Diabetes & Endocrinology and JAMA. 

Recent publications

Do people prefer to take part in a clinical trial from home or come to site? Julia Kopanz, Bart Lagerwaard, Jorien Veldwijk, Julia K Mader, Dietrich Tews, Thomas T van Sloten, Diederick E Grobbee, Mira G P Zuidgeest,
BMJ Open, 2025, vol. 15
Dementia Risk in People With Type 1 Diabetes and Associated Risk Factors Milena Jancev, Björn Eliasson, Hertzel C. Gerstein, Katarina Eeg-Olofsson, Tali Cukierman-Yaffe, Geert Jan Biessels, J. Hans DeVries, Frank L.J. Visseren, Naveed Sattar, Thomas T. van Sloten
Diabetes Care, 2025, vol. 48, p.1888-1895
Genetic variation in the glucagon-like peptide-1 receptor protein encoding region is associated with higher heart rate variability, but not with neurodegeneration of the brain, retina, and peripheral nerves Frank C T van der Heide, Indra L M Steens, Archana Singh-Manoux, Séverine Sabia, Tan Lai Zhou, Sebastian Köhler, Miranda T Schram, Carla J H van der Kallen, Tos T J M Berendschot, Carroll A B Webers, Marleen M J van Greevenbroek, Anke Wesselius, Ilja C W Arts, Jacobus F A Jansen, Walter H Backes, Thomas T van Sloten, Gabriëlla A M Blokland, Coen D A Stehouwer
Cardiovascular Diabetology, 2025, vol. 24, p.1-12
Arterial stiffness and atherosclerosis and incident cardiovascular events and all-cause mortality in individuals with manifest cardiovascular disease with and without type 2 diabetes Jan F de Leijer, Frank L J Visseren, Birgitta K Velthuis, Ynte M Ruigrok, Jaco J M Zwanenburg, Manon G van der Meer, Martin Teraa, Pim A de Jong, Thomas T van Sloten,
Diabetic Medicine, 2025, vol. 42
Type 2 diabetes and depression via microvascular dysfunction, neurodegeneration, inflammation, advanced glycation end products (AGEs), arterial stiffness Indra L M Steens, Miranda T Schram, Alfons J H M Houben, Tos T J M Berendschot, Annemarie Koster, Hans Bosma, Simone J P M Eussen, Bastiaan E de Galan, Thomas T van Sloten
Diabetes, Obesity & Metabolism, 2025, vol. 27, p.4847-4858
Association between retinal microvasculature and cerebral small vessel function in type 2 diabetes Jan F de Leijer, Stanley D T Pham, Tessa A C M Vissers, Lieza G Exalto, Reinier O Schlingemann, Jeroen S W Siero, Jaco J M Zwanenburg, Rafael Simó, Noemi Lois, Thomas T van Sloten, Geert Jan Biessels,
Diabetes, Obesity & Metabolism, 2025, vol. 27, p.5346-5350

Fellowships & Awards

- European Foundation for the Study of Diabetes (EFSD). Multi-system challenges in diabetes program. Title: Microvasculature-brain interaction in type 2 diabetes: an ultrahigh MRI study.

- Diabetes Young Fellowship Award. Dutch Diabetes Research Foundation. Title: A microvascular imaging approach to understand brain diseases in type 2 diabetes. 

- Dutch Research Council Zon-MW; Veni grant. Title: Does microvascular dysfunction contribute to late-life depression?

- Dutch Heart Association; Dr. E. Dekker clinical scientist grant; Title: Late-life depression: a cerebral microvascular disorder?

External positions

Lid redactie van website diabetesgeneeskunde - Meedenken over inhoud van de website - Diabetesgeneeskunde.nl