Stefan Willems

Associate Professor - medical

Biography

Dr Stefan Willems was trained in medicin (2003 cum laude Catholic University Leuven) with a PhD in molecular pathology (2010, Leiden University) and specialized in pathology (2011, LUMC). After postdoc positions at Harvard Medical School (Gygilab) and NKI  (Bernardslab) he has been working as a pathologist with special interest in molecular pathology and diagnostics. He is co-director of the molecular pathology lab in the University Medical Center Utrecht. He is associate professor in pathology and head of the molecular head and neck cancer line within the UMC Utrecht (1 postdoc, 8 PhDs). He is also affiliated with the department of pathology of the NKI-AvL and performs here translational head and neck research. He is board member of the PALGA Foundation.

Recent publications

Differential transcriptional invasion signatures from patient derived organoid models define a functional prognostic tool for head and neck cancer Peter D Haughton, Wisse Haakma, Theofilos Chalkiadakis, Gerben E Breimer, Else Driehuis, Hans Clevers, Stefan Willems, Stefan Prekovic, Patrick W B Derksen
Oncogene, 2024, vol. 43, p.2463-2474
Clinicopathological Factors as Predictors for Establishment of Patient Derived Head and Neck Squamous Cell Carcinoma Organoids W W B de Kort, R Millen, E Driehuis, L A Devriese, R J J van Es, S M Willems
Head and neck pathology, 2024, vol. 18
Combined spatial Keratin expression profiles at the invasive front represent a prognostic classifier for head and neck cancer Peter D. Haughton, Wisse E. Haakma, Sven van Kempen, Emma J. de Ruiter, Stefan M. Willems, Patrick W.B. Derksen
Oral Oncology Reports, 2024, vol. 10
Spatial correlation between in vivo imaging and immunohistochemical biomarkers Hilde J.G. Smits, Edwin Bennink, Lilian N. Ruiter, Gerben E. Breimer, Stefan M. Willems, Jan W. Dankbaar, Marielle E.P. Philippens
Translational Oncology, 2024, vol. 48
Prognostic value of histopathologic traits independent of stromal tumor-infiltrating lymphocyte levels in chemotherapy-naïve patients with triple-negative breast cancer L W de Boo, K Jóźwiak, N D Ter Hoeve, P J van Diest, M Opdam, Y Wang, M K Schmidt, V de Jong, S Kleiterp, S Cornelissen, D Baars, R H T Koornstra, E D Kerver, T van Dalen, A D Bins, A Beeker, S M van den Heiligenberg, P C de Jong, S D Bakker, R C Rietbroek, I R Konings, R Blankenburgh, R M Bijlsma, A L T Imholz, N Stathonikos, W Vreuls, J Sanders, E H Rosenberg, E A Koop, Z Varga, C H M van Deurzen, A L Mooyaart, A Córdoba, E Groen, J Bart, S M Willems, V Zolota, J Wesseling, A Sapino, E Chmielik, A Ryska, A Broeks, A C Voogd, E van der Wall, S Siesling, R Salgado, G M H E Dackus, M Hauptmann, M Kok, S C Linn
ESMO open, 2024, vol. 9
Considerable interlaboratory variation in PD-L1 positivity for head and neck squamous cell carcinoma in the Netherlands— A nationwide evaluation study Maaike Anna Hempenius, Bregje M. Koomen, Ivette A.G. Deckers, Sjoukje F. Oosting, Stefan M. Willems, Bert van der Vegt
Histopathology, 2024, vol. 85, p.133-142