Profile photo Stefan Prekovic

Stefan Prekovic

Assistant Professor

Strategic program(s):

Biography

Born and raised in a quaint Serbian town, I earned my BSc/MSc degrees from the University of Belgrade before relocating to Belgium. There, I joined Frank Claessens' lab, exploring the androgen receptor's role in diverse diseases. Later, as a postdoctoral researcher at the Netherlands Cancer Institute, I worked with Wilbert Zwart on investigating transcription factor action in various cancer types using omics, screening, and computational methodologies.

Strategic program(s):

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Research groups

Chromatin-related factors and cellular plasticity

Research aim

The group focuses on chromatin-related factors and their effects on cellular phenotypes, employing a range of state-of-the-art omics techniques. Our objective is to uncover targetable pathways that can effectively eliminate cancer cells.

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Recent publications

Correction to Julia S. Scott, Loubna Al Ayadi, Emmanouela Epeslidou, Roan H. van Scheppingen, Anna Mukha, Lucas J.T. Kaaij, Catrin Lutz, Stefan Prekovic
Oncogene, 2025, vol. 44, p.2561–2562
Large-scale Characterization of Orthotopic Cell Line–Derived Xenografts Identifies TGFβ Signaling as a Key Regulator of Breast Cancer Morphology and Aggressiveness Catrin Lutz, Xue Chao, Bim de Klein, Jinhyuk Bhin, Madelon Badoux, Timo Eijkman, Apostolos P. Nikolakopoulos, Stefan J. Hutten, Natalie Proost, Bjørn Siteur, Marieke van de Ven, Ji Ying Song, Jacco van Rheenen, Jessica Morgner, Stefan Prekovic, Jos Jonkers
Cancer Research, 2025, vol. 85, p.2608-2625
The epigenetic landscape of brain metastasis Aoibhín M. Powell, Louise Watson, Lara Luzietti, Stefan Prekovic, Leonie S. Young, Damir Varešlija
Oncogene, 2025, vol. 44, p.2227–2239
Glycolytic reprogramming shapes the histone acetylation profile of activated CD4+ T cells in juvenile idiopathic arthritis Enric Mocholi, Edward Corrigan, Theo Chalkiadakis, Can Gulersonmez, Edwin Stigter, Bas Vastert, Jorg van Loosdregt, Stefan Prekovic, Paul J. Coffer
Cell Reports, 2025, vol. 44
Tumor-derived colorectal cancer organoids induce a unique Treg cell population by directing CD4+ T cell differentiation Sonia Aristin Revilla, Cynthia L. Frederiks, Stefan Prekovic, Enric Mocholi, Onno Kranenburg, Paul J. Coffer
iScience, 2025, vol. 28
NAC regulates metabolism and cell fate in intestinal stem cells Sofia Ramalho, Ferhat Alkan, Stefan Prekovic, Katarzyna Jastrzebski, Eric Pintó Barberà, Liesbeth Hoekman, Maarten Altelaar, Cecilia de Heus, Nalan Liv, Maria J. Rodríguez-Colman, Mehmet Yilmaz, Rob van der Kammen, Juliette Fedry, Mark C. de Gooijer, Saskia Jacoba Elisabeth Suijkerbuijk, William J. Faller, Joana Silva
Science advances, 2025, vol. 11, p.eadn9750