Profile photo Jeroen Siero

Jeroen Siero

Associate Professor

Strategic program(s):

Biography

My research focuses on vascular MRI. Clinical translation, MRI method and ultrasonic gradient coils development, image analysis. Applications: cerebrovascular diseases, stroke and small vessel disease, and brain physiology on perfusion, oxygen metabolism and neurovascular coupling.


keywords: clinical translation | cerebrovascular disease | functional MRI | ultra-high field | gradient coils

Research groups

Precision imaging

Research aim

Our research lines incorporate inventions of MR technology to be able to see the unseen for advancing medicine. Our clinical research focus areas are cancer, dementia, cardiovascular, stroke and MSK.

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Translational neuroimaging group

Research aim

To develop and apply advanced MRI methods for (pre)clinical research on neuronal and cerebrovascular biology in order to: 1) unravel critical aspects of brain impairment and recovery 2) advance brain treatments (focus: cerebrovascular diseases).

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Recent publications

The contribution of the vascular architecture and cerebrovascular reactivity to the BOLD signal formation across cortical depth Emiel C A Roefs, Wouter Schellekens, Mario G Báez-Yáñez, Alex A Bhogal, Iris I A Groen, Matthias J P van Osch, Jeroen C W Siero, Natalia Petridou
Imaging neuroscience (Cambridge, Mass.), 2024, vol. 2, p.1-19
Assessment of Small Vessel Function Using 7T MRI in Patients With Sporadic Cerebral Small Vessel Disease Hilde Van Den Brink, Stanley Pham, Jeroen C. Siero, Tine Arts, Laurien Onkenhout, Hugo Kuijf, Jeroen Hendrikse, Joanna M. Wardlaw, Martin Dichgans, Jaco J. Zwanenburg, Geert Jan Biessels
Neurology, 2024, vol. 102
A silent echo-planar spectroscopic imaging readout with high spectral bandwidth MRSI using an ultrasonic gradient axis Edwin Versteeg, Kyung Min Nam, Dennis W.J. Klomp, Alex A. Bhogal, Jeroen C.W. Siero, Jannie P. Wijnen
Magnetic Resonance in Medicine, 2024, vol. 91, p.2247-2256
On the influence of the vascular architecture on Gradient Echo and Spin Echo BOLD fMRI signals across cortical depth Mario Gilberto Báez-Yáñez, Jeroen C W Siero, Vanja Curcic, Matthias J P van Osch, Natalia Petridou
2024
Fast and silent MRI using nonlinear gradient fields at the ultrasonic gradient switching frequency of 20 kHz with a Point Spread Function framework reconstruction Michael J B McGrory, Edwin Versteeg, Alessandro Sbrizzi, Cornelis A T van den Berg, Dennis Klomp, Jeroen C W Siero
Magnetic Resonance in Medicine, 2024, vol. 92, p.2734-2748
A fully synthetic three-dimensional human cerebrovascular model based on histological characteristics to investigate the hemodynamic fingerprint of the layer BOLD fMRI signal formation Mario Gilberto Báez-Yáñez, Wouter Schellekens, Alex A Bhogal, Emiel C A Roefs, Matthias J P van Osch, Jeroen CW Siero, Natalia Petridou
2024, p.1-38

Fellowships & Awards

2019: Fellowship Young Talent 2019- Rudolf Magnus

External positions

Affiliated Associate Professor, Spinoza Centre for Neuroimaging Amsterdam - Affiliated Associate Professor - supervision PhD students, aid in MR sequences - Spinoza Centre for Neuroimaging Amsterdam