Saskia de Jager

Associate Professor

Strategic program(s):

Contact

sjager@umcutrecht.nl

Pure profile

Research groups

Transplantation

Research aim

We aim to understand how infection and immunity impact transplantation. By uncovering these mechanisms, we aim to improve patient care, reduce rejection and complications, and enhance success rates, benefiting society with better health outcomes.

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Molecular science & therapy in heart failure

Research aim

Current available therapies for chronic heart diseases only alleviate symptoms and prevent the disease from becoming worse. We aim to improve our understanding of heart failure and develop new strategies for therapy.

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Recent publications

All publications

Primary Graft Dysfunction in Lung Transplantation Jitte Jennekens, Sue A Braithwaite, Bart Luijk, Niels P van der Kaaij, Nienke Vrisekoop, Saskia C A de Jager, Linda M de Heer
International Journal of Molecular Sciences, 2025, vol. 26

Clinical relevance and outcome of routine endomyocardial biopsy to detect rejection after heart transplantation Leendert C Kieviet, Steven A Muller, Mariusz K Szymanski, Manon G van der Meer, M Louis Handoko, Saskia Z H Rittersma, Saskia C A de Jager, Egidius E van Aarnhem, Annelotte Vos, Pim van der Harst, Linda W van Laake, Marish I F J Oerlemans
JHLT Open, 2025, vol. 9

Human Cardiac Microtissues Display Improved Engraftment and Survival in a Porcine Model of Myocardial Infarction Evelyne Demkes, Aina Cervera-Barea, Patricia Ebner-Peking, Martin Wolf, Sarah Hochmann, Amy S. Scheren, Mayke Bijsterveld, C. Marlies van Oostveen, Marlijn Jansen, Joyce Visser, Wiebke Triebert, Caroline Halloin, Johannes G.G. Dobbe, Judith de Vos, Melanie Schürz, Joachim Danmayr, Maurice C.G. Aalders, Gerard J.J. Boink, Klaus Neef, Dirk Strunk, Robert Zweigerdt, Saskia C.A. de Jager, Joost P.G. Sluijter
Journal of Cardiovascular Translational Research, 2025, vol. 18, p.512-528

Hypoxia and TNF-alpha modulate extracellular vesicle release from human induced pluripotent stem cell-derived cardiomyocytes Margarida Viola, Maarten P. Bebelman, Renee G.C. Maas, Willemijn S. de Voogt, Frederik J. Verweij, Cor S. Seinen, Saskia C.A. de Jager, Pieter Vader, Dirk Michiel Pegtel, Joost Petrus Gerardus Sluijter
Journal of Extracellular Vesicles, 2024, vol. 13

A novel cardioprotective perfusion protocol prevents functional decline during extended normothermic ex situ heart perfusion of marginal porcine hearts Mats T Vervoorn, Sjoerd van Tuijl, Elisa M Ballan, Selma E Kaffka Genaamd Dengler, Saskia C A de Jager, Joost P G Sluijter, Pieter A Doevendans, Niels P van der Kaaij
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2024, vol. 44, p.961-971

A Perspective on the Added Value of Red Blood Cells during Cardiac Hypothermic Oxygenated Perfusion Mats T Vervoorn, Elisa M Ballan, Selma E Kaffka Genaamd Dengler, Veronique M F Meijborg, Saskia C A de Jager, Richard Van Wijk, Niels P van der Kaaij
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2024, vol. 44, p.285-288