Saskia de Jager

Associate Professor

Strategic program(s):

Contact

sjager@umcutrecht.nl

Pure profile

Research groups

Transplantation

Research aim

We aim to understand how infection and immunity impact transplantation. By uncovering these mechanisms, we aim to improve patient care, reduce rejection and complications, and enhance success rates, benefiting society with better health outcomes.

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Molecular science & therapy in heart failure

Research aim

Current available therapies for chronic heart diseases only alleviate symptoms and prevent the disease from becoming worse. We aim to improve our understanding of heart failure and develop new strategies for therapy.

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Recent publications

All publications

Hypoxia and TNF-alpha modulate extracellular vesicle release from human induced pluripotent stem cell-derived cardiomyocytes Margarida Viola, Maarten P. Bebelman, Renee G.C. Maas, Willemijn S. de Voogt, Frederik J. Verweij, Cor S. Seinen, Saskia C.A. de Jager, Pieter Vader, Dirk Michiel Pegtel, Joost Petrus Gerardus Sluijter
Journal of Extracellular Vesicles, 2024, vol. 13

A novel cardioprotective perfusion protocol prevents functional decline during extended normothermic ex situ heart perfusion of marginal porcine hearts Mats T Vervoorn, Sjoerd van Tuijl, Elisa M Ballan, Selma E Kaffka Genaamd Dengler, Saskia C A de Jager, Joost P G Sluijter, Pieter A Doevendans, Niels P van der Kaaij
The Journal of heart and lung transplantation : the official publication of the International Society for Heart... Show all

A Perspective on the Added Value of Red Blood Cells during Cardiac Hypothermic Oxygenated Perfusion Mats T Vervoorn, Elisa M Ballan, Selma E Kaffka Genaamd Dengler, Veronique M F Meijborg, Saskia C A de Jager, Richard Van Wijk, Niels P van der Kaaij
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2024, vol. 44, p.285-288

Past Trends and Future Directions of Cardiac Regenerative Medicine - A Systematic Analysis of Clinical Trial Registries Maaike Wulfse, Mats T Vervoorn, Jantijn J G J Amelink, Elisa M Ballan, Saskia C A de Jager, Joost P G Sluijter, Pieter A Doevendans, Peter-Paul M Zwetsloot, Niels P Van der Kaaij
Journal of Cardiovascular Translational Research, 2024, vol. 18, p.209-220

Cold exposure increases circulating fibroblast growth factor 21 in the eveninin males and females Carlijn A. Hoekx, Borja Martinez-Tellez, Maaike E. Straat, Magdalena M.A. Verkleij, Mirjam Kemmeren, Sander Kooijman, Martin Uhrbom, Saskia C.A. de Jager, Patrick C.N. Rensen, Mariëtte R. Boon
Endocrine connections, 2024, vol. 13

Growth differentiation factor 15 is not modified after weight loss induced by liraglutide in South Asians and Europids with type 2 diabetes mellitus Carlijn A. Hoekx, Maaike E. Straat, Maurice B. Bizino, Huub J. van Eyk, Hildebrandus J. Lamb, Johannes W.A. Smit, Ingrid M. Jazet, Saskia C.A. de Jager, Mariëtte R. Boon, Borja Martinez-Tellez
Experimental physiology, 2024, vol. 109, p.1292-1304