Sabine Linn

Full Professor

Strategic program(s):

Contact

slinn2@umcutrecht.nl

Pure profile

Research groups

Translational breast cancer research group

Research aim

We aim to optimize early diagnosis and treatment of breast cancer, especially rare breast cancers like pregnancy associated, male & lobular breast cancer. We refine tissue diagnostics with molecular techniques/AI, and apply nipple fluid/blood tests.

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Recent publications

All publications

De-escalation of axillary treatment in the event of a positive sentinel lymph node biopsy in cT1-2 N0 breast cancer treated with mastectomy Sabine R. de Wild, Lori M. van Roozendaal, Johannes H.W. de Wilt, Thijs van Dalen, Jos A. van der Hage, Frederieke H. van Duijnhoven, Janine M. Simons, Robert Jan Schipper, Linda de Munck, Sander M.J. van Kuijk, Liesbeth J. Boersma, Sabine C. Linn, Marc B.I. Lobbes, Philip M.P. Poortmans, Vivianne C.G. Tjan-Heijnen, Koen K.B.T. van de Vijver, Jolanda de Vries, A. Helen Westenberg, Luc J.A. Strobbe, Marjolein L. Smidt
British Journal of Surgery, 2024, vol. 111

High-dose chemotherapy for patients with stage III breast cancer with homologous recombination deficiency Joost G.E. Verbeek, Leyla Azarang, Luis E. Pilli, Vincent M.T. De Jong, Agnes Jager, Sabine C. Linn, Valesca P. Retèl, Wim H. Van Harten
Acta oncologica (Stockholm, Sweden), 2024, vol. 63, p.701-709

Tumor-Infiltrating Lymphocytes in Patients with Stage i Triple-Negative Breast Cancer Untreated with Chemotherapy Veerle C.M. Geurts, Sara Balduzzi, Tessa G. Steenbruggen, Sabine C. Linn, Sabine Siesling, Sunil S. Badve, Angela Demichele, Michail Ignatiadis, Roberto A. Leon-Ferre, Matthew P. Goetz, Antonio C. Wolff, Natalie Klar, Stefan Michiels, Sherene Loi, Sylvia Adams, Hugo M. Horlings, Gabe S. Sonke, Roberto Salgado, Marleen Kok
JAMA Oncology, 2024, vol. 10, p.1077-1086

Academic Uphill Battle to Personalize Treatment for Patients With Stage II/III Triple-Negative Breast Cancer Marleen Kok, Robbert Jan Gielen, Sylvia Adams, Jochen K. Lennerz, Priyanka Sharma, Sibylle Loibl, Erin Reardon, Gabe Sonke, Sabine Linn, Suzette Delaloge, Denis Lacombe, Tim Robinson, Sunil Badve, Miguel Martin, Justin M. Balko, Michail Ignatiadis, Giuseppe Curigliano, Antonio C. Wolff, Elizabeth A. Mittendorf, Sherene Loi, Lajos Pusztai, Sara M. Tolaney, Roberto Salgado
Journal of Clinical Oncology, 2024, vol. 42, p.3523-3529

Predictive gene expression profile for adjuvant taxane benefit in breast cancer in the MATADOR trial Mark Opdam, Annelot G.J. van Rossum, Marlous Hoogstraat, Gergana Bounova, Hugo M. Horlings, Erik van Werkhoven, Ingrid A.M. Mandjes, A. Elise van Leeuwen – Stok, Sander Canisius, Harm van Tinteren, Alex L.T. Imholz, Johanneke E.A. Portielje, Monique E.M.M. Bos, Sandra Bakker, Jelle Wesseling, Lennart Kester, Jacco van Rheenen, Emiel J. Rutgers, Renee X. de Menezes, Lodewyk F.A. Wessels, Marleen Kok, Hendrika M. Oosterkamp, Sabine C. Linn, Marcel Soesan, Rianne M. Oosterkamp, Frank Jeurissen, Nir Weijl, Karin J. Beelen, Aart van Bochove, Gerty de Klerk, Suzan Vrijaldenhoven, Annette van der Velden, Hiltje de Graaf, Marielle Smeets, Jetske Meerum Terwogt, Jolanda Schrama, Philomeen Kuijer, Hanneke Wilmink, Ronald Hoekstra, Judith Kroep, Hans F.M. Pruijt, Leander van Gerven, Allert H. Vos, Frans Erdkamp, Willemien G. van Leeuwen-Breuk, Alexander de Graeff,
iScience, 2024, vol. 27

Olaparib Addition to Maintenance Bevacizumab Therapy in Ovarian Carcinoma with BRCA -Like Genomic Aberrations Philip C. Schouten, Sandra Schmidt, Kerstin Becker, Holger Thiele, Peter Nürnberg, Lisa Richters, Corinna Ernst, Isabelle Treilleux, Jacques Medioni, Florian Heitz, Carmela Pisano, Yolanda Garcia, Edgar Petru, Sakari Hietanen, Nicoletta Colombo, Ignace Vergote, Shoji Nagao, Sabine C. Linn, Eric Pujade-Lauraine, Isabelle Ray-Coquard, Philipp Harter, Eric Hahnen, Rita K. Schmutzler
JAMA network open, 2024, vol. 7