Ruben van Eijk

Associate Professor

Strategic program(s):

Contact

reijk3@umcutrecht.nl

Pure profile

Research groups

Clinical spectrum of motor neuron disease

Research aim

Motor neuron disease (MND) are a collection of disorder that primarily lead to progressive weakness and/or spasticity. The goal is better understand and treat the extensive clinical heterogeneity in MND.

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Recent publications

All publications

Motor function score changes in severe 5q spinal muscular atrophy during risdiplam treatment Lina M. Vermeer, Fay Lynn Asselman, Ruben P.A. van Eijk, Inge Cuppen, Danny R. van der Woude, Bea M.H.E.A. Visser–de Heus, Saskia M.J. Hogervorst, Thijs J. Ruyten, Bart Bartels, Renske I. Wadman, W. Ludo van der Pol
EClinicalMedicine, 2026, vol. 97

Quantifying motor unit loss prior to functional impairment in muscles affected by amyotrophic lateral sclerosis Boudewijn T.H.M. Sleutjes, Anna Bystrup Jacobsen, Hatice Tankisi, N. Gorkem Sirin, A. Emre Oge, Robert D. Henderson, Pieter A. van Doorn, Leonard H. van den Berg, Ruben P.A. van Eijk
Clinical Neurophysiology Practice, 2026, vol. 11, p.538-542

Speech-based digital endpoints track ALS progression and align with standard clinical outcomes Michael Neumann, Hardik Kothare, Meredith Bartlett, Oliver Roesler, Christiane Suendermann-Oeft, Abhishek Hosamath, Lakshmi Arbatti, David Pautler, David Suendermann-Oeft, Diego Cadavid, Robert H. Scannevin, Ines Hoffmann, Anil Tarachandani, Tara Haley, Shane Raines, Philip Van Damme, Pentti Tienari, Eino Solje, Manu Jokela, Angela Genge, Colleen O’Connell, Ruben P.A.van Eijk, Leonard H.van den Berg, Vikram Ramanarayanan
Scientific Reports, 2026, vol. 16

Effectiveness of stratified blended physiotherapy versus usual physiotherapy for neck and shoulder pain Mark L. van Tilburg, Corelien J.J. Kloek, Nadine E. Foster, J. Bart Staal, Ruben P.A. van Eijk, Raymond W.J.G. Ostelo, Martijn F. Pisters, Cindy Veenhof
Annals of physical and rehabilitation medicine, 2026, vol. 69

Small RNA sequencing identifies serum tDR-1:34-Gly-GCC tiRNA levels as a biomarker for survival in amyotrophic lateral sclerosis Koen C. Demaegd, Lindy Kool, Sharada Baindoor, Paul D. Donovan, Junyi Su, Henk Jan Westeneng, Ruben P.A. van Eijk, Grainne Geoghegan, Elena Perez Morrissey, Luise Halang, Koen Poesen, Pegah Masrori, Hesham A.Y. Gibriel, Elisabeth Jirström, Morten T. Venø, Jørgen Kjems, Orla Hardiman, Jan H. Veldink, Kevin Kenna, Leonard H. van den Berg, Philip Van Damme, Jochen H.M. Prehn, Michael A. van Es
iScience, 2026, vol. 29

Heterogeneity in the Analysis of the ALSFRS-R in ALS Clinical Trials and its Effect on the Validity and Precision of Trial Conclusions Daphne N. Weemering, Jordi W.J. van Unnik, Angela Genge, Leonard H. van den Berg, Ruben P.A. van Eijk
Neurology, 2026, vol. 106