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Profile photo Ruben van Eijk

Ruben van Eijk

Associate Professor

Strategic program(s):

Brain

Strategic program(s):

Brain

Contact

reijk3@umcutrecht.nl
Pure profile

Research groups

Clinical spectrum of motor neuron disease

Research aim

Motor neuron disease (MND) are a collection of disorder that primarily lead to progressive weakness and/or spasticity. The goal is better understand and treat the extensive clinical heterogeneity in MND.

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Recent publications

All publications
An open-label Phase 2a study to assess the safety and tolerability of trimetazidine in patients with amyotrophic lateral sclerosis Ruben P.A. van Eijk, Frederik J. Steyn, Mark R. Janse van Mantgem, Angela Schmidt, Myrte Meyjes, Sally Allen, Dara V. Daygon, Jean Philippe Loeffler, Ammar Al-Chalabi, Leonard H. van den Berg, Robert D. Henderson, Shyuan T. Ngo
Brain communications, 2025, vol. 7
Fast Analgesic Effect in Response Test with Topical Phenytoin Cream Correlates with Prolonged Pain Relief After Extended Use in Painful Diabetic Neuropathy David J. Kopsky, Alexander F.J.E. Vrancken, Ruben P.A. van Eijk, Ricardo Alvarez-Jimenez, Karolina M. Szadek, Remko Liebregts, Monique A.H. Steegers
Pharmaceuticals, 2025, vol. 18
How Consistent are Speech-Based Biomarkers in Remote Tracking of ALS Disease Progression Across Languages? A Case Study of English and Dutch Hardik Kothare, Michael Neumann, Cathy Zhang, Jackson Liscombe, Jordi W.J. van Unnik, Lianne C.M. Botman, Leonard H. van den Berg, Ruben P.A. van Eijk, Vikram Ramanarayanan
2024, p.2005-2009
Attrition and discontinuation in amyotrophic lateral sclerosis clinical trials Ruben P.A. van Eijk, Floris T. van Loon, Jordi W.J. van Unnik, Daphne N. Weemering, Georgios Seitidis, Dimitris Mavridis, Leonard H. van den Berg, Stavros Nikolakopoulos
Journal of Neurology, 2024, vol. 272
Variation in Resting Metabolic Rate Affects Identification of Metabolic Change in Geographically Distinct Cohorts of Patients with ALS Cory J. Holdom, Mark R. Janse Van Mantgem, Ji He, Stephanie L. Howe, Pamela A. McCombe, Dongsheng Fan, Leonard H. Van Den Berg, Robert D. Henderson, Ruben P.A. Van Eijk, Frederik J. Steyn, Shyuan T. Ngo
Neurology, 2024, vol. 102
Living systematic review and comprehensive network meta-analysis of ALS clinical trials Floris T. Van Loon, Georgios Seitidis, Dimitris Mavridis, Jordi W.J. van Unnik, Daphne N. Weemering, Leonard H. van den Berg, Ilianna Bethani, Stavros Nikolakopoulos, Ruben P.A. van Eijk
BMJ Open, 2024, vol. 14