Researchers Roelie Wösten-van Asperen

Roelie Wösten-van Asperen

Associate Professor

Strategic program(s):

Biography

Roelie Wösten-van Asperen is a pediatric-intensivist at the PICU of the Wilhelmina Children’s Hospital in Utrecht. She started her fellowship in pediatric intensive care in 2002. After finalization of her fellowship, she has been a consultant pediatric intensivist in the Emma Children’s Hospital/Academic Medical Center, Amsterdam. In 2011, she defended her thesis ‘The role of the renin-angiotensin system in acute lung injury’ at the University of Amsterdam.

After almost 15 years (in January 2016), she moved from the PICU of the Emma Children’s Hospital to the PICU of the Wilhelmina Children’s Hospital in Utrecht. Together with Prof. Marry van den Heuvel of the Princess Máxima Center for Pediatric Oncology, she started a research group on pediatric cancer patients at the PICU.

She is currently chair of the PICU Oncology Kids in Europe Research group (POKER), a research consortium comprising of 21 PICU’s which are adhered to large pediatric oncological centers in 11 different countries (Austria, Belgium, Denmark, Germany, France, Italy, Poland, Spain, Switzerland, the Netherlands, and the UK). Our mission is to improve our understanding and our ability to appropriately treat these patients, thereby improving outcomes of children with cancer who are admitted to the PICU.

Education/training

1988-1993 Medical Biology, Groningen University, Groningen, The Netherlands Degree: MSc (cum laude)

1991-1995 Medicine, Groningen University, Groningen, The Netherlands. Degree: MSc (cum laude)

1995-1997 Medical Degree Groningen University, Groningen, The Netherlands. Degree: MD (cum laude)

1997-2002 Training in pediatrics, University of Leiden (1997-1999) and University of Groningen (2000-2002), The Netherlands

2002-2006 Fellowship pediatric intensive care medicine, Emma Children’s Hospital/Academic Medical Center, Amsterdam, The Netherlands

2005-2011 PhD ‘The role of the renin angiotensin system in acute lung injury’, University of Amsterdam, Amsterdam, The Netherlands

Researchline

Pediatric cancer patients at the PICU: identifying prognostic factors influencing PICU admission and outcome of pediatric cancer patients.

Strategic program(s):

Contact

rasperen@umcutrecht.nl

Pure profile

Recent publications

All publications

The Burden of Pediatric Critical Illness Among Pediatric Oncology Patients in Low- and Middle-income Countries Alejandra Gabela, Roelie M Wösten-van Asperen, Anita V Arias, Carlos Acuña, Zebin Al Zebin, Eliana Lopez-Baron, Parthasarathi Bhattacharyya, Lauren Duncanson, Daiane Ferreira, Sanjeeva Gunasekera, Samantha Hayes, Jennifer McArthur, Vaishnavi Divya Nagarajan, Maria Puerto Torres, Jocelyn Rivera, Elizabeth Sniderman, Jordan Wrigley, Huma Zafar, Asya Agulnik
Critical Reviews in Oncology/Hematology, 2024, vol. 203

Healthcare costs related to respiratory syncytial virus in paediatric intensive care units in the Netherlands Emily W.E.M. Phijffer, Joanne G. Wildenbeest, Carole N.M. Brouwer, Matthijs de Hoog, Martin C.J. Kneyber, Sofie Maebe, Anneliese Nusmeier, Maaike A. Riedijk, Roelie M. Wösten-van Asperen, Job B.M. van Woensel, Louis J. Bont, Geert J.W. Frederix
The Lancet Regional Health - Europe, 2024, vol. 43

Paediatric cancer patients with severe sepsis or septic shock at the PICU with positive microbiological results do worse than those with negative results: a retrospective cohort study Lisette Veling, Fernanne van Wolffelaar, J van der Bruggen, Michiel van der Flier, Wim Tissing, RM Wösten-van Asperen
Intensive Care Medicine Paediatric and Neonatal, 2024, vol. 2

Evidence for Beneficial Effect of Daily Use of Mechanical Insufflation-Exsufflation in Patients With Neuromuscular Diseases Esther S Veldhoen, Roosmarijn van der Wal, Laura P Verweij-van den Oudenrijn, Roelie M Wösten-van Asperen, Michael A Gaytant, Cornelis K van der Ent, W Ludo van der Pol, Erik Hj Hulzebos
Respiratory Care, 2023, vol. 68, p.531-546

Genomic investigations of unexplained acute hepatitis in children Sofia Morfopoulou, Sarah Buddle, Oscar Enrique Torres Montaguth, Laura Atkinson, José Afonso Guerra-Assunção, Mahdi Moradi Marjaneh, Riccardo Zennezini Chiozzi, Nathaniel Storey, Luis Campos, J. Ciaran Hutchinson, John R. Counsell, Gabriele Pollara, Sunando Roy, Cristina Venturini, Juan F. Antinao Diaz, Ala’a Siam, Luke J. Tappouni, Zeinab Asgarian, Joanne Ng, Killian S. Hanlon, Alexander Lennon, Andrew McArdle, Agata Czap, Joshua Rosenheim, Catarina Andrade, Glenn Anderson, Jack C.D. Lee, Rachel Williams, Charlotte A. Williams, Helena Tutill, Sietse Nagelkerke, Michiel van der Flier, Wim J.E. Tissing, Roelie M. Wösten-van Asperen, Sebastiaan J. Vastert, Daniel C. Vijlbrief, Louis J. Bont, Tom F.W. Wolfs, Coco R. Beudeker, Dennie Tempel, Danielle van Keulen, Ronald de Groot, Michiel van der Flier, Koen van Aerde, J. Heidema, C. J. Miedema, Ilse Jongerius, J. M. van den Berg, D. Schonenberg, Judith Zandstra, , ,
Nature, 2023, vol. 617, p.564-573

Adeno-associated virus 2 infection in children with non-A–E hepatitis Antonia Ho, Richard Orton, Rachel Tayler, Patawee Asamaphan, Vanessa Herder, Chris Davis, Lily Tong, Katherine Smollett, Maria Manali, Jay Allan, Konrad Rawlik, Sarah E. McDonald, Elen Vink, Louisa Pollock, Louise Gannon, Clair Evans, Jim McMenamin, Kirsty Roy, Kimberly Marsh, Titus Divala, Matthew T.G. Holden, Michael Lockhart, David Yirrell, Sandra Currie, Maureen O’Leary, David Henderson, Samantha J. Shepherd, Celia Jackson, Rory Gunson, Alasdair MacLean, Neil McInnes, Amanda Bradley-Stewart, Richard Battle, Jill A. Hollenbach, Paul Henderson, Miranda Odam, Primrose Chikowore, Wilna Oosthuyzen, J. M.Merlijn van den Berg, Sietse Nagelkerke, Michiel van der Flier, Wim J.E. Tissing, Roelie M. Wösten-van Asperen, Sebastiaan J. Vastert, Daniel C. Vijlbrief, Louis J. Bont, Tom F.W. Wolfs, Coco R. Beudeker, Dennie Tempel, Danielle van Keulen, ,
Nature, 2023, vol. 617, p.555-563

Fellowships & Awards

Funding as Co-PI:

2012 Academic Medical Center Graduate School Scholarship: Impact of age on the pulmonary renin-angiotensin system in acute respiratory distress syndrome (Euro 205K)

2017 Research grant supported by KiKa: Identifying the critically ill pediatric cancer patient. (Euro 590K)