Roel Deckers

Associate Professor

Strategic program(s):

Biography

I received an MSc of Biomedical Engineering from Eindhoven University of Technology, before completing my PhD in Biomedical Physics at Université Bordeaux I in France. I am currently an Associate Professor of the Imaging & Oncology division at UMC Utrecht. My research focuses on imaging and manipulating the tumor microenvironment with ultrasound to improve drug delivery. I am PI of two projects (NWO-OTP and UHR-KWF) focusing on ultrasound-based interventions to improve tumor drug distributions. I mentored more than 10 researchers to their PhD defense (currently 2 PhD students ongoing), and I am involved in (inter-)national research networks.

Strategic program(s):

Contact

rdecker2@umcutrecht.nl

Pure profile

Research groups

Image-guided Therapeutic Ultrasound

Research aim

We develop image-guided interventions based on therapeutic use of ultrasound. We work closely with clinicians and basic scientists to advance translation, evaluation and adoption of therapeutic ultrasound for a positive impact on patient outcomes.

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Recent publications

All publications

Mechanical HIFU and immune checkpoint inhibition Vera Mekers, Mirjam de Visser, Karijn Suijkerbuijk, Clemens Bos, Chrit Moonen, Roel Deckers, Gosse Adema
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2024, vol. 41

Ultrasound-directed enzyme-prodrug therapy (UDEPT) using self-immolative doxorubicin derivatives Karolin Roemhild, Helena C. Besse, Bi Wang, Quim Peña, Qingxue Sun, Daiki Omata, Burcin Ozbakir, Clemens Bos, Hans W. Scheeren, Gert Storm, Josbert M. Metselaar, Haijun Yu, Ruth Knüchel-Clarke, Fabian Kiessling, Chrit T.W. Moonen, Roel Deckers, Yang Shi, Twan Lammers
Theranostics, 2022, vol. 12, p.4791-4801

Ultrasound and microbubbles for the treatment of ocular diseases Charis Rousou, Carl C.L. Schuurmans, Arto Urtti, Enrico Mastrobattista, Gert Storm, Chrit Moonen, Kai Kaarniranta, Roel Deckers
Pharmaceutics, 2021, vol. 13

Ultrasound-Mediated Drug Delivery With a Clinical Ultrasound System Josanne S de Maar, Charis Rousou, Benjamin van Elburg, Hendrik J Vos, Guillaume P R Lajoinie, Clemens Bos, Chrit T W Moonen, Roel Deckers
Frontiers in Pharmacology, 2021, vol. 12

A Doxorubicin-Glucuronide Prodrug Released from Nanogels Activated by High-Intensity Focused Ultrasound Liberated β-Glucuronidase Helena C Besse, Yinan Chen, Hans W Scheeren, Josbert M Metselaar, Twan Lammers, Chrit T W Moonen, Wim E Hennink, Roel Deckers
Pharmaceutics, 2020, vol. 12

Spatial heterogeneity of nanomedicine investigated by multiscale imaging of the drug, the nanoparticle and the tumour environment Josanne Sophia De Maar, Alexandros Marios Sofias, Tiffany Porta Siegel, Rob J. Vreeken, Chrit Moonen, Clemens Bos, Roel Deckers
Theranostics, 2020, vol. 10, p.1884-1909