Profile photo Richard van Hillegersberg

Richard van Hillegersberg

Full Professor

Strategic program(s):

Biography

Richard van Hillegersberg attended medical school in Rotterdam, the Netherlands. In 1993 he received his PhD with honor at the Department of Surgery, Erasmus MC in Rotterdam. From 1994-2000, he was trained in General Surgery in Rotterdam. From 2001-2002 he was fellow of Surgical Oncology in the Academic Medical Center and Antoni van Leeuwenhoek Netherlands Cancer Center Amsterdam. Since 2003 he is appointed as staff surgeon at the University Medical Center Utrecht. From 2009 he is a full professor of gastrointestinal oncology. Research is focused on Upper GI minimally invasive and robotic surgery, surgical imaging and genetic profiling. He has authored over 15 chapters in textbooks concerning robotic forgut surgery and over 500 articles in international peer-reviewed journals. From 2018 he is chairman of the Educational committee of the European Society for Diseases for the Esophagus (ESDE) and member of the education committee of ISDE, he is associate editor of Diseases of the Esophagus and Digestive Surgery, founder and chairman of the Upper GI International Robotic Association (UGIRA).

Strategic program(s):

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Research groups

Upper GI

Research aim

Our research concentrates on surgical treatment of esophageal and gastric cancer, addressing diagnostics, surgical techniques, postoperative recovery, and prognostic outcomes. By interdisciplinary collaboration we strive to enhance patient care.

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Recent publications

Prognostic impact of positive peritoneal cytology (POPEC) in gastric cancer Richard Owen, Swathikan Chidambaram, Khalid Shamiyah, Jessie A. Elliott, Jakob Hedberg, Sivesh Kamarajah, Frederik Klevebro, Marcel Andre Schneider, Lana Fourie, Christian Gutschow, Magnus Nilsson, Ewen Griffiths, Ricardo Rosati, Javed Sultan, Manuel Pera, Peter Grimminger, Guillaume Piessen, Clarisse Eveno, Jelle Ruurda, Richard van Hillegersberg, John V. Reynolds, Mark van Berge Henegouwen, Suzanne Gisbertz, Jimmy B.Y. So, Nick Maynard, Sheraz Markar, Vanessa Peronace, Ellen A. Boyle, Aileen Pang, Candy Yap, Daryl Chia, Guowei Kim, Asim Shabbir, Amina Youcef, Khalid Bhatti, Kammy Keywani, Ricardo Calef, Eren Uzun, Mariagiulia Dal Cero, James Halle-Smith, Tim Bagnell, Lianne Triemstra, Matthias Josef, Kerstin Neuschütz, Andrea Cossu, John Saunders
Surgical Oncology Insight, 2025, vol. 2
The evolving concept of conversion surgery for upfront unresectable upper gastrointestinal and hepato-pancreato-biliary cancers Giampaolo Perri, Jennie Engstrand, Robin D Wright, Sebastiaan F C Bronzwaer, Tiuri E Kroese, Biying Huang, Belkacem Acidi, Alessandro Vitale, Hop S Tran Cao, Richard van Hillegersberg, Magnus Nilsson, Ernesto Sparrelid, Matthew H G Katz, Giovanni Marchegiani, Umberto Cillo
BJS open, 2025, vol. 9
Does the SANO trial really move us toward organ preservation for esophageal cancer? Sheraz R. Markar, Mark Van Berge Henegouwen, Christiane Bruns, Lorenzo Ferri, Richard Van Hillegersberg, Wayne Hofstetter, Magnus Nilsson
Diseases of the Esophagus, 2025, vol. 38
SANO trial Sheraz R. Markar, Mark Van Berge Henegouwen, Christiane Bruns, Lorenzo Ferri, Richard van Hillegersberg, Wayne Hofstetter, Magnus Nilsson
The Lancet Oncology, 2025, vol. 26, p.e338
Response to two invited commentaries on ‘Paravertebral versus EPidural Analgesia in Minimally Invasive Esophageal resectioN (PEPMEN) Cezanne D. Kooij, Richard van Hillegersberg, Mark I. van Berge Henegouwen
AME Surgical Journal, 2025, vol. 5
Robot-Assisted Minimally Invasive Esophagectomy Cezanne D Kooij, Lucas Goense, B Feike Kingma, Richard van Hillegersberg, Jelle P Ruurda
Digestive Surgery, 2025, vol. 42, p.204-212

Fellowships & Awards

2014-present. Principle investigator. Cost effectiveness of laparoscopic gastrectomy  as an alternative to open gastrectomy for gastric cancer (LOGICA trial). ClinTrial.gov: NCT02248519. ZonMw (837002502) Eu 400.000

2014-present. Principle investigator. Esophagectomy for Patients With Esophageal Cancer and Cervical Lymph Node Metastases (NODE trial). ClinTrial.gov: NCT02426879

2017-present. Intuitive Clinical Research Grant for the project “The International Registry for Robot-assisteted Minimally Invasive Esophagectomy” (RAMIE). Unrestricted Grant $ 50.000

2017-present. International Database collaboration Robotic esophagectomy, Intuitive Surgical, Unrestricted Grant. Eu 50.000

 2017-present. Coordinating Investigator of International Centers. Surgery for adenocarcinoma of the gastroesophageal junction (GEJ) type II: transthoracic esophagectomy vs. transhiatal extended gastrectomy (CARDIA trial). Analyzing in a multicenter international setting the optimal surgical strategy for tumors at the oesophago-gastric junction. This trial is now recruiting in collaboration with The University of Koln. Deutsches Register Klinischer Studien. DRKS-number: 00016923. Federal Ministry for Education and Research. Bundesministerium für Bildung und Forschung (BMBF) (grant number 01KG1816). Eu 1.940.000

2018-present. G.J.Meijer. Preoperative Image-guided Identification of Response to Neoadjuvant Chemoradiotherapy in Esophageal Cancer (PRIDE). ClinTrial.gov: NCT03474341. KWF (10291) Eu 890.260

2020-present Principal investigator. Paravertabral catheter versus epidural anagesia in minimally invasive esophageal resection : a RCT (PEPMEN trail). ZonMw (852002004) Eu 392.650

External positions

member - advisor - Dutch Guidelines Oesophageal Cancer (FMS)

Associate editor - paper editor - Digestive Surgery

member board and educational committee - management - The International Society for Diseases of the Esophagus

Associate editor - paper editor - Diseases of the Esophagus

member board and educational committee - management - European Society Diseases of the Esopghagus (ESDE)

Onderwijs robotchirurgie - Slokdarmchirurgie, robotchirurgie - Intuitive Surgical

editorial board - chirurgische oncologie - Springer Healthcare Benelux

Proctor - training van chirurgen in robot chirurgie - Intuitive Surgical

member scientific committee - management - United European Gastroenterology (UEG)

board member - chirurgische oncologie - DICA

Bestuur - Penningmeester - Stichting Chirurgische Oncologie

member - management - European Digestive Surgery

member board - advisor - Dutch Upper GI Cancer Audit (DUCA)