Profile photo Richard van Hillegersberg

Richard van Hillegersberg

Full Professor

Strategic program(s):

Biography

Richard van Hillegersberg attended medical school in Rotterdam, the Netherlands. In 1993 he received his PhD with honor at the Department of Surgery, Erasmus MC in Rotterdam. From 1994-2000, he was trained in General Surgery in Rotterdam. From 2001-2002 he was fellow of Surgical Oncology in the Academic Medical Center and Antoni van Leeuwenhoek Netherlands Cancer Center Amsterdam. Since 2003 he is appointed as staff surgeon at the University Medical Center Utrecht. From 2009 he is a full professor of gastrointestinal oncology. Research is focused on Upper GI minimally invasive and robotic surgery, surgical imaging and genetic profiling. He has authored over 15 chapters in textbooks concerning robotic forgut surgery and over 500 articles in international peer-reviewed journals. From 2018 he is chairman of the Educational committee of the European Society for Diseases for the Esophagus (ESDE) and member of the education committee of ISDE, he is associate editor of Diseases of the Esophagus and Digestive Surgery, founder and chairman of the Upper GI International Robotic Association (UGIRA).

Strategic program(s):

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Research groups

Upper GI

Research aim

Our research concentrates on surgical treatment of esophageal and gastric cancer, addressing diagnostics, surgical techniques, postoperative recovery, and prognostic outcomes. By interdisciplinary collaboration we strive to enhance patient care.

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Recent publications

Conversion Therapy for Stage IV Gastric Cancer Tae Han Kim, Ichiro Uyama, Sun Young Rha, Maria Bencivenga, Jiyeong An, Lucjan Wyrwicz, Dong Hoe Koo, Richard van Hillegersberg, Keun Wook Lee, Guoxin Li, Takaki Yoshikawa, Brian Badgwell, Sylvie Lorenzen, In Ho Kim, In Seob Lee, Hye Sook Han, Hur Hoon
Journal of Gastric Cancer, 2025, vol. 25, p.133-152
Oligometastatic Esophagogastric Cancer Tiuri E. Kroese, Sebastiaan F.C. Bronzwaer, Peter S.N. van Rossum, Hanneke W.M. van Laarhoven, Richard van Hillegersberg
Current Oncology Reports, 2025, vol. 27, p.30-36
Real-world outcomes of the CROSS regimen in patients with resectable esophageal or gastro-esophageal junction adenocarcinoma Hanneke van Laarhoven, Rob Verhoeven, Mark van Berge Henegouwen, Nadia Haj Mohammad, Richard van Hillegersberg, Marije Slingerland, Christina T. Muijs, Bas Wijnhoven, Bianca Mostert, Laurens Beerepoot, Grard Nieuwenhuijzen, Sarah Derks, Peter S.N. van Rossum
EClinicalMedicine, 2025, vol. 80
The course of physical fitness and nutritional status in patients following prehabilitation before esophageal cancer surgery Elja A.E. Reijneveld, Cezanne D. Kooij, Jaap J. Dronkers, B. Feike Kingma, Joyce M.A. Stel, Miron Sauer, Richard van Hillegersberg, Peter van Duijvendijk, Sandra Beijer, Jelle P. Ruurda, Cindy Veenhof,
European Journal of Surgical Oncology, 2025, vol. 51
Clinical practice guidelines for esophagogastric junction cancer Yuko Kitagawa, Satoru Matsuda, Takuji Gotoda, Ken Kato, Bas Wijnhoven, Florian Lordick, Pradeep Bhandari, Hirofumi Kawakubo, Yasuhiro Kodera, Masanori Terashima, Kei Muro, Hiroya Takeuchi, Paul F. Mansfield, Yukinori Kurokawa, Jimmy So, Stefan Paul Mönig, Kohei Shitara, Sun Young Rha, Yelena Janjigian, Daisuke Takahari, Ian Chau, Prateek Sharma, Jiafu Ji, Giovanni de Manzoni, Magnus Nilsson, Paulo Kassab, Wayne L. Hofstetter, Elizabeth Catherine Smyth, Sylvie Lorenzen, Yuichiro Doki, Simon Law, Do Youn Oh, Khek Yu Ho, Tomoyuki Koike, Lin Shen, Richard van Hillegersberg, Hisato Kawakami, Rui Hua Xu, Zev Wainberg, Naohisa Yahagi, Yeong Yeh Lee, Rajvinder Singh, Min Hee Ryu, Ryu Ishihara, Zili Xiao, Chika Kusano, Heike Irmgard Grabsch, Hiroki Hara, Ken Ichi Mukaisho, Tomoki Makino, Mitsuro Kanda, Eisuke Booka, Sho Suzuki, Waku Hatta, Motohiko Kato, Akira Maekawa, Akihito Kawazoe, Shun Yamamoto, Izuma Nakayama, Yukiya Narita, Han Kwang Yang, Masahiro Yoshida, Takeshi Sano
Gastric Cancer, 2024, vol. 27, p.401-425
Management of locally advanced adenocarcinoma of the oesophagus and oesophagogastric junction Teus J Weijs, Hanneke W M van Laarhoven, Bas P L Wijnhoven, Jelle P Ruurda, Richard van Hillegersberg
The Lancet Gastroenterology and Hepatology, 2024, vol. 9, p.103-104

Fellowships & Awards

2014-present. Principle investigator. Cost effectiveness of laparoscopic gastrectomy  as an alternative to open gastrectomy for gastric cancer (LOGICA trial). ClinTrial.gov: NCT02248519. ZonMw (837002502) Eu 400.000

2014-present. Principle investigator. Esophagectomy for Patients With Esophageal Cancer and Cervical Lymph Node Metastases (NODE trial). ClinTrial.gov: NCT02426879

2017-present. Intuitive Clinical Research Grant for the project “The International Registry for Robot-assisteted Minimally Invasive Esophagectomy” (RAMIE). Unrestricted Grant $ 50.000

2017-present. International Database collaboration Robotic esophagectomy, Intuitive Surgical, Unrestricted Grant. Eu 50.000

 2017-present. Coordinating Investigator of International Centers. Surgery for adenocarcinoma of the gastroesophageal junction (GEJ) type II: transthoracic esophagectomy vs. transhiatal extended gastrectomy (CARDIA trial). Analyzing in a multicenter international setting the optimal surgical strategy for tumors at the oesophago-gastric junction. This trial is now recruiting in collaboration with The University of Koln. Deutsches Register Klinischer Studien. DRKS-number: 00016923. Federal Ministry for Education and Research. Bundesministerium für Bildung und Forschung (BMBF) (grant number 01KG1816). Eu 1.940.000

2018-present. G.J.Meijer. Preoperative Image-guided Identification of Response to Neoadjuvant Chemoradiotherapy in Esophageal Cancer (PRIDE). ClinTrial.gov: NCT03474341. KWF (10291) Eu 890.260

2020-present Principal investigator. Paravertabral catheter versus epidural anagesia in minimally invasive esophageal resection : a RCT (PEPMEN trail). ZonMw (852002004) Eu 392.650

External positions

member - advisor - Dutch Guidelines Oesophageal Cancer (FMS)

Associate editor - paper editor - Digestive Surgery

member board and educational committee - management - The International Society for Diseases of the Esophagus

Associate editor - paper editor - Diseases of the Esophagus

member board and educational committee - management - European Society Diseases of the Esopghagus (ESDE)

Onderwijs robotchirurgie - Slokdarmchirurgie, robotchirurgie - Intuitive Surgical

editorial board - chirurgische oncologie - Springer Healthcare Benelux

Proctor - training van chirurgen in robot chirurgie - Intuitive Surgical

member scientific committee - management - United European Gastroenterology (UEG)

board member - chirurgische oncologie - DICA

Bestuur - Penningmeester - Stichting Chirurgische Oncologie

member - management - European Digestive Surgery

member board - advisor - Dutch Upper GI Cancer Audit (DUCA)