Profile photo René Kahn

René Kahn

Full Professor

Biography

Dr René Kahn is Professor and until 2017, was Chair of the Department of Psychiatry and Head of the Division of Neurosciences at the University Medical Center, Utrecht, The Netherlands. In 1995 he received a Fulbright Scholarship for study at Yale and subsequently did a Fellowship in Biological Psychiatry at the Montefiore Hospital and Albert Einstein College of Medicine in New York. He then moved to the Mount Sinai School of Medicine where he conducted schizophrenia research and became Unit Chief of one of the research units.

Dr Kahn has received many grants for his research into the origins and treatment of schizophrenia. His current research interests include neuroimaging in schizophrenia and the genetic dissection of complex traits in specific psychiatric disorders. He has published over 500 research papers and book chapters. He is on the editorial boards of Schizophrenia research, Schizophrenia Bulletin, Early Interventions in Psychiatry and European Neuropsychopharmacology. He was both Treasurer and Vice-President of the European College for Neuropsychopharmacology and currently is President-Elect of the Schizophrenia International Research Society. He sat on the Neuroscience andd Mental Health Board of the Medical Research Council of the UK and was on the scientific advisory group for CNS of the European Medicines Agency. He leads a large EU-funded study, OPTiMiSE, on developing a treatment algorithm in first episode schizophrenia. He is honorary lifetime professor at Jilin University in Changchun, P.R. China and a member of the Royal Netherlands Academy of Arts and Sciences.

As of January 2017, he is appointed head of the Department of Psychiatry at Icahn School of Medicine at Mount Sinai in New York. His main tasks at UMC Utrecht are now: coaching his PhD students and coordinating research projects.

Most recent key publications

1: Kahn RS, Fleischhacker WW, Boter H, Davidson M, Vergouwe Y, Keet IP, Gheorghe MD, Rybakowski JK, Galderisi S, Libiger J, Hummer M, Dollfus S, López-Ibor JJ, Hranov LG, Gaebel W, Peuskens J, Lindefors N, Riecher-Rössler A, Grobbee DE, EUFEST study group. E
2: van der Schot AC, Vonk R, Brans RG, van Haren NE, Koolschijn PC, Nuboer V, Schnack HG, van Baal GC, Boomsma DI, Nolen WA, Hulshoff Pol HE, Kahn RS. Influence of genes and environment on brain volumes in twin pairs concordant and discordant for bipolar disorder. Arch Gen Psychiatry. 2009 Feb,66(2):142-51
3: van der Schot AC, Vonk R, Brouwer RM, van Baal GC, Brans RG, van Haren NE, Schnack HG, Boomsma DI, Nolen WA, Pol HE, Kahn RS. Genetic and environmental influences on focal brain density in bipolar disorder. Brain. 2010 Sep 12
4: van Haren NE, Schnack HG, Cahn W, van den Heuvel MP, Lepage C, Collins L, Evans AC, Hulshoff Pol HE, Kahn RS Changes in cortical thickness during the course of illness in schizophrenia Arch Gen Psychiatry. 2011 Sep,68(9):871-80
5: van Haren NE, Rijsdijk F, Schnack HG, Picchioni MM, Toulopoulou T, Weisbrod M, Sauer ,H, van Erp TG, Cannon TD, Huttunen MO, Boomsma DI, Hulshoff Pol HE, Murray RM, Kahn RS. The genetic and environmental determinants of the association between brain abnormalities and schizophrenia: the schizophrenia twins and relatives consortium. Biol Psychiatry. 2012 May 15,71(10):915-21

Recent publications

Sulcal Widening in Schizophrenia Maps onto Sulcal Hubs and Energy-Synaptic Genes Javier González-Peñas, Hugo G Schnack, Carmen Rueda Hernández, Covadonga M Díaz-Caneja, Celia de la Fuente Montero, Marta Martín Echave, Alberto Mora, Niels Janssen, Pedro M Gordaliza, Alberto Fernández-Pena, Daniel Martín de Blas, Susana Carmona, Wiepke Cahn, Neeltje E M van Haren, René S Kahn, Hilleke Hulshoff Pol, Celso Arango, Yasser Alemán-Gómez, Joost Janssen
2026
Accurate DNA methylation predictor for C9orf72 repeat expansion alleles in the pathogenic range Naren Ramesh, Alexandria Evans, Kevin Wojta, Zhongan Yang, Marco P. Boks, René S. Kahn, Sterre C.M. de Boer, Sven J. van der Lee, Yolande A.L. Pijnenburg, Lianne M. Reus, Roel A. Ophoff
Human Genetics and Genomics Advances, 2026, vol. 7
Premorbid functioning trajectories and the one-year course of cognitive performance in first-episode psychosis Margot I.E. Slot, Hendrika H. van Hell, Inge Winter van Rossum, George Gifford, Paola Dazzan, Arija Maat, Lieuwe De Haan, Benedicto Crespo-Facorro, Birte Y. Glenthøj, Colm McDonald, Thérèse van Amelsvoort, Celso Arango, Irina Falkenberg, Barnaby Nelson, Silvana Galderisi, Mark Weiser, Gabriele Sachs, Anke Maatz, Jun Soo Kwon, Philip McGuire, René S. Kahn
Schizophrenia Research: Cognition, 2026, vol. 43
Defining suicidality phenotypes for genetic studies Sarah M.C. Colbert, Eric T. Monson, Ole A. Andreassen, Olatunde Ayinde, Peter B. Barr, Cosmin A. Bejan, Zuriel Ceja, Hilary Coon, Emily DiBlasi, Howard J. Edenberg, Joel Gelernter, Alexander S. Hatoum, Anastasia Izotova, Emma C. Johnson, Erin A. Kaufman, Henry R. Kranzler, Maria Koromina, Kelli Lehto, Woojae Myung, John I. Nurnberger, Alessandro Serretti, Jordan W. Smoller, Murray B. Stein, Clement C. Zai, Annette Erlangsen, Marie Gaine, Lourdes Martorell, Reeteka Sud, Claudio Toma, Tim B. Bigdeli, Nathan A. Kimbrel, Douglas Ruderfer, Anna R. Docherty, J. John Mann, Niamh Mullins, Lea Zillich, Zeynep Yilmaz, Naomi R. Wray, D. Blake Woodside, Stephanie H. Witt, Virginia Willour, Leanne M. Williams, David C. Whiteman, Thomas Werge, Frank Wendt, Myrna M. Weissman, Roel A. Ophoff, René S. Kahn, Wiepke Cahn, Marco P. Boks,
Molecular Psychiatry, 2025, vol. 30, p.6144-6154
Confirmatory factor analysis of competing PANSS negative symptom models Arsime Demjaha, Daniel Stahl, Celso Arango, Birte Glenthøj, Roberto Rodriguez-Jimenez, Covadonga Martinez Díaz-Caneja, Lone Baandrup, Bjørn Ebdrup, Maria Paz Garcia-Portlla, Maria Diaz-Marsa, Inge Winter-van Rossum, Rene Kahn, Paola Dazzan, Philip McGuire
BJPsych open, 2025, vol. 12
Ensuring generalizability and clinical utility in mental health care applications Fiona Coutts, Sergio Mena, Esin Ucur, W Wolfgang Fleischhacker, Rene Kahn, Jeffrey Lieberman, Alkomiet Hasan, Oliver Howes, Christoph Correll, Nikolaos Koutsouleris, Paris Alexandros Lalousis
Psychiatry and Clinical Neurosciences, 2025, vol. 80, p.64-75

Fellowships & Awards

1985 Fulbright Scholarship
1989 Ramaer Medaille
2009 Member Royal Netherlands Academy for Arts and Sciences