Profile photo Pim van der Harst

Pim van der Harst

Full Professor

Strategic program(s):

Biography

I am an interventional cardiologist and scientist and head of the department of cardiology of the University Medical Center Utrecht. My clinical work includes the percutaneous treatment of obstructive coronary artery disease, including acute myocardial infarction. My translational research focusses on the analysis of big and complex data (e.g. genetic, ehr, imaging), including the use of machine learning and cloud computing, to improve our understanding and the early detection of coronary artery disease and heart failure. To this end we use large population based cohorts, including the Dutch PREVEND and LifeLine cohorts and the UK Biobank. Data on my "omics" research can be found our my website: www.cardiomics.net  In my clinical translational research I am also working on advanced image analysis, device interventions, machine learning, deep learning, and e/m Health to further improve and personalize care for our patients. Currently ongoing diagnostic imaging studies in include the REPLACE-IT (replacement of invasive coronary angiography) and the EARLY-SYNERGY (early detection of obstructive coronary artery disease; www.early-synergy.nl) studies. Currently interventional studies include the GIPS-IV, AXES and MRI-MC studies. Many of my projects based on collaborations with the most influential and creative individuals and research groups in the world.

Research groups

Inherited heart disease (cardiogenetics)

Research aim

We aim to enhance patient and family lives impacted by inherited cardiomyopathies. Our efforts target gene and variant identification, disease mechanisms, factors influencing disease outcomes, therapy optimization, and exploration of novel therapies.

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Recent publications

Primary care patients' perspectives on CT coronary calcium scoring and exercise electrocardiography Moniek Koopman, Robert Willemsen, Carine Doggen, Bastiaan Kietselaer, Peter van Ooijen, Jan Willem Gratama, Richard Braam, Geert-Jan Dinant, Rykel van Bruggen, Pim van der Harst, Rozemarijn Vliegenthart
European Journal of General Practice, 2025, vol. 31
Deep representation learning of electrocardiogram reveals biological insights in cardiac phenotypes and cardiovascular diseases Ming Wai Yeung, Rutger R. van de Leur, Jan Walter Benjamins, Melle B. Vessies, Bram Ruijsink, Esther Puyol-Antón, J. Peter van Tintelen, Niek Verweij, René van Es, Pim van der Harst
iScience, 2025, vol. 28
Timelines, targets, and transitions in cardiovascular care Pim van der Harst
Netherlands Heart Journal, 2025, vol. 33, p.249
Reply to H. Nathoe, Pim van der Harst
Netherlands Heart Journal, 2025, vol. 33, p.287
From guidelines to patient-centred action Pim van der Harst
Netherlands Heart Journal, 2025, vol. 33, p.215
Clinical relevance and outcome of routine endomyocardial biopsy to detect rejection after heart transplantation Leendert C Kieviet, Steven A Muller, Mariusz K Szymanski, Manon G van der Meer, M Louis Handoko, Saskia Z H Rittersma, Saskia C A de Jager, Egidius E van Aarnhem, Annelotte Vos, Pim van der Harst, Linda W van Laake, Marish I F J Oerlemans
JHLT Open, 2025, vol. 9

Fellowships & Awards

Awards

2015

Winner of Humanimal – One Health Innovation Challenge 2015 with the Durrer Center (of which I was Chief Scientific Officer). Price for “Best Professional Idea Flevoland” for our Open One Health Biobank proposal (€ 50,000.--)

2013Scientific Excellence Award from the Board of the UMCG (€ 100,000.--)
2010 Excellence Award from the Netherlands Foundation for Cardiovascular Excellence for Scientific, Clinical and Presenting Excellence (€ 50,000.--)

Fellowships

2012NWO Clinical Fellowship (90.700.441); Systems and functional genomics strategies to identify novel vulnerability genes for heart failure. €160,000.--
2007VENI Fellowship (916.76.170) of the Innovational Research Incentives Scheme of the Netherlands Organization for Scientific Research (NWO); Telomere length in cardiovascular disease; differential expression and prognostic value (€ 248,000.--)
2008ICIN Fellowship (€ 45,000.--) of the Interuniversity Cardiology Institute of the Netherlands

         

 

External positions

Editor-in-Chief - editor - bohn stafleu van loghum

Lid van de Raad van Toezicht - vele raakvlakken - Netherlands Heart Institute

begeleiden promovendi met afronden van hun promotie, eerste promotor - soortgelijk - Universitair Medisch Centrum Groningen

National member of Scientific Advisory Board LifeLines Cohort Study - ja, inhoudelijk advies - LifeLines B.V.

Nucleus member of the center for circulatory health at the UMC Utrecht - ja - UMC Utrecht

begeleiden promovendi met afronden van hun promotie, eerste promotor - soortgelijk - Universitair Medisch Centrum Groningen

National member of Scientific Advisory Board LifeLines Cohort Study - ja, inhoudelijk advies - LifeLines B.V.

Nucleus member of the center for circulatory health at the UMC Utrecht - ja - UMC Utrecht