Full Professor
Strategic program(s):
Biography
I am an interventional cardiologist and scientist and head of the department of cardiology of the University Medical Center Utrecht. My clinical work includes the percutaneous treatment of obstructive coronary artery disease, including acute myocardial infarction. My translational research focusses on the analysis of big and complex data (e.g. genetic, ehr, imaging), including the use of machine learning and cloud computing, to improve our understanding and the early detection of coronary artery disease and heart failure. To this end we use large population based cohorts, including the Dutch PREVEND and LifeLine cohorts and the UK Biobank. Data on my "omics" research can be found our my website: www.cardiomics.net In my clinical translational research I am also working on advanced image analysis, device interventions, machine learning, deep learning, and e/m Health to further improve and personalize care for our patients. Currently ongoing diagnostic imaging studies in include the REPLACE-IT (replacement of invasive coronary angiography) and the EARLY-SYNERGY (early detection of obstructive coronary artery disease; www.early-synergy.nl) studies. Currently interventional studies include the GIPS-IV, AXES and MRI-MC studies. Many of my projects based on collaborations with the most influential and creative individuals and research groups in the world.
Research aim
We aim to enhance patient and family lives impacted by inherited cardiomyopathies. Our efforts target gene and variant identification, disease mechanisms, factors influencing disease outcomes, therapy optimization, and exploration of novel therapies.
Go to groupAwards
2015 |
Winner of Humanimal – One Health Innovation Challenge 2015 with the Durrer Center (of which I was Chief Scientific Officer). Price for “Best Professional Idea Flevoland” for our Open One Health Biobank proposal (€ 50,000.--) |
2013 | Scientific Excellence Award from the Board of the UMCG (€ 100,000.--) |
2010 | Excellence Award from the Netherlands Foundation for Cardiovascular Excellence for Scientific, Clinical and Presenting Excellence (€ 50,000.--) |
Fellowships
2012 | NWO Clinical Fellowship (90.700.441); Systems and functional genomics strategies to identify novel vulnerability genes for heart failure. €160,000.-- |
2007 | VENI Fellowship (916.76.170) of the Innovational Research Incentives Scheme of the Netherlands Organization for Scientific Research (NWO); Telomere length in cardiovascular disease; differential expression and prognostic value (€ 248,000.--) |
2008 | ICIN Fellowship (€ 45,000.--) of the Interuniversity Cardiology Institute of the Netherlands |
Editor-in-Chief - editor - bohn stafleu van loghum
Lid van de Raad van Toezicht - vele raakvlakken - Netherlands Heart Institute
begeleiden promovendi met afronden van hun promotie, eerste promotor - soortgelijk - Universitair Medisch Centrum Groningen
National member of Scientific Advisory Board LifeLines Cohort Study - ja, inhoudelijk advies - LifeLines B.V.
Nucleus member of the center for circulatory health at the UMC Utrecht - ja - UMC Utrecht
begeleiden promovendi met afronden van hun promotie, eerste promotor - soortgelijk - Universitair Medisch Centrum Groningen
National member of Scientific Advisory Board LifeLines Cohort Study - ja, inhoudelijk advies - LifeLines B.V.
Nucleus member of the center for circulatory health at the UMC Utrecht - ja - UMC Utrecht