Profile photo Pim van der Harst

Pim van der Harst

Full Professor

Strategic program(s):

Biography

I am an interventional cardiologist and scientist and head of the department of cardiology of the University Medical Center Utrecht. My clinical work includes the percutaneous treatment of obstructive coronary artery disease, including acute myocardial infarction. My translational research focusses on the analysis of big and complex data (e.g. genetic, ehr, imaging), including the use of machine learning and cloud computing, to improve our understanding and the early detection of coronary artery disease and heart failure. To this end we use large population based cohorts, including the Dutch PREVEND and LifeLine cohorts and the UK Biobank. Data on my "omics" research can be found our my website: www.cardiomics.net  In my clinical translational research I am also working on advanced image analysis, device interventions, machine learning, deep learning, and e/m Health to further improve and personalize care for our patients. Currently ongoing diagnostic imaging studies in include the REPLACE-IT (replacement of invasive coronary angiography) and the EARLY-SYNERGY (early detection of obstructive coronary artery disease; www.early-synergy.nl) studies. Currently interventional studies include the GIPS-IV, AXES and MRI-MC studies. Many of my projects based on collaborations with the most influential and creative individuals and research groups in the world.

Research groups

Inherited heart disease (cardiogenetics)

Research aim

We aim to enhance patient and family lives impacted by inherited cardiomyopathies. Our efforts target gene and variant identification, disease mechanisms, factors influencing disease outcomes, therapy optimization, and exploration of novel therapies.

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Recent publications

A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels Paul S. de Vries, Paula Reventun, Michael R. Brown, Adam S. Heath, Jennifer E. Huffman, Ngoc Quynh Le, Allison Bebo, Jennifer A. Brody, Gerard Temprano-Sagrera, Laura M. Raffield, Ayse Bilge Ozel, Florian Thibord, Deepti Jain, Joshua P. Lewis, Benjamin A.T. Rodriguez, Nathan Pankratz, Kent D. Taylor, Ozren Polasek, Ming Huei Chen, Lisa R. Yanek, German D. Carrasquilla, Riccardo E. Marioni, Marcus E. Kleber, David Alexandre Trégouët, Jie Yao, Ruifang Li-Gao, Peter K. Joshi, Stella Trompet, Angel Martinez-Perez, Mohsen Ghanbari, Tom E. Howard, Alex P. Reiner, Marios Arvanitis, Kathleen A. Ryan, Traci M. Bartz, Igor Rudan, Nauder Faraday, Allan Linneberg, Lynette Ekunwe, Gail Davies, Graciela E. Delgado, Pierre Suchon, Xiuqing Guo, Frits R. Rosendaal, Lucija Klaric, Raymond Noordam, Frank van Rooij, Joanne E. Curran, Marsha M. Wheeler, Pim van der Harst, ,
Blood, 2024, vol. 143, p.1845-1855
Intracardiac echocardiography-guided biopsies for right-sided intracardiac tumors Arco J Teske, Gian-Manuel Jimenez-Rodriguez, Adriaan O Kraaijeveld, Lysette N Broekhuizen, Dirk van Osch, Eelke H Gort, Anna V Rhenen, Pim Vd Harst, Michiel Voskuil
Catheterization and Cardiovascular Interventions, 2024, vol. 104, p.862-868
Novel loci and biomedical consequences of iron homoeostasis variation Elias Allara, Steven Bell, Rebecca Smith, Spencer J. Keene, Dipender Gill, Liam Gaziano, Deisy Morselli Gysi, Feiyi Wang, Vinicius Tragante, Amy Mason, Savita Karthikeyan, R. Thomas Lumbers, Emmanuela Bonglack, Willem Ouwehand, David J. Roberts, Joseph Dowsett, Sisse Rye Ostrowski, Margit Hørup Larsen, Henrik Ullum, Ole Birger Pedersen, Søren Brunak, Karina Banasik, Christian Erikstrup, David Westergaard, Thomas Werge, Mie Topholm Bruun, Unnur Þorsteinsdóttir, Lise Wegner Thørner, Hreinn Stefánsson, Kari Stefansson, Erik Sørensen, Michael Schwinn, Klaus Rostgaard, Palle Duun Rohde, Þórunn Rafnar, Liam James Elgaard Quinn, Mette Nyegaard, Janna Nissen, Christina Mikkelsen, Susan Mikkelsen, Mette Kongstad, Bertram Dalskov Kjerulff, Kathrine Kaspersen, Andrew Joseph Schork, Bitten Aagaard Jensen, Jakob Hjorth von Stemann, Henrik Hjalgrim, Lotte Hindhede, Annette Peters, Pim van der Harst, ,
Communications biology, 2024, vol. 7
Prognostic significance of echocardiographic deformation imaging in adult congenital heart disease Philippe J van Rosendael, Karim Taha, Marco Guglielmo, Arco J Teske, Pim van der Harst, Gertjan Sieswerda, Maarten J Cramer, Heleen B van der Zwaan
European Journal of Clinical Investigation, 2024, vol. 54
Evaluation of the 2021 ESC recommendations for family screening in hereditary transthyretin cardiac amyloidosis Steven A Muller, Belén Peiró-Aventin, Giulia Biagioni, Giacomo Tini, Giulia Saturi, Christina Kronberger, Anouk Achten, Stephan Dobner, Wouter P Te Rijdt, Alessio Gasperetti, Anneline S J M Te Riele, Guerino G Varrà, Alberto Ponziani, Alexander Hirsch, Aldostefano Porcari, Manon G van der Meer, Mattia Zampieri, Pim van der Harst, Andreas Kammerlander, Elena Biagini, J Peter van Tintelen, Emanuele Barbato, Folkert W Asselbergs, Silvia Menale, Christoph Gräni, Marco Merlo, Michelle Michels, Christian Knackstedt, Christian Nitsche, Simone Longhi, Beatrice Musumeci, Francesco Cappelli, Pablo Garcia-Pavia, Marish I F J Oerlemans
European Journal of Heart Failure, 2024, vol. 26, p.2025-2034
Healthcare consumption of patients with left ventricular assist device Lena Bosch, Peter-Paul M Zwetsloot, Maaike Brons, Gerardus P J van Hout, Manon G van der Meer, Mariusz K Szymanski, Anne-Marie Troost-Oppelaar, Faiz Z Ramjankhan, Pim van der Harst, Monica Gianoli, Marish I F J Oerlemans, Linda W van Laake
Netherlands Heart Journal, 2024, vol. 32, p.317-325

External positions

Editor-in-Chief - editor - bohn stafleu van loghum

Lid van de Raad van Toezicht - vele raakvlakken - Netherlands Heart Institute

begeleiden promovendi met afronden van hun promotie, eerste promotor - soortgelijk - Universitair Medisch Centrum Groningen

National member of Scientific Advisory Board LifeLines Cohort Study - ja, inhoudelijk advies - LifeLines B.V.

Nucleus member of the center for circulatory health at the UMC Utrecht - ja - UMC Utrecht

begeleiden promovendi met afronden van hun promotie, eerste promotor - soortgelijk - Universitair Medisch Centrum Groningen

National member of Scientific Advisory Board LifeLines Cohort Study - ja, inhoudelijk advies - LifeLines B.V.

Nucleus member of the center for circulatory health at the UMC Utrecht - ja - UMC Utrecht