Associate Professor
Strategic program(s):
Biography
I am an associate professor in clinical trial methodology and statistics working within the Department of Data Science and Biostatistics of the Julius Center where I lead the Clinical Trial Methodology & Statistical Consultation team. My interests lie in innovative clinical trial methodology (both development and application) and adaptive methods, trials-within cohorts and trials in rare diseases in particular. I am the Trial Methodology Lead for U-TRIAL and workpackage leader for the Adaptive Trial Platform WP in the ONCODE-ACCELERATOR growthfund project. I am the chair of the UMC Utrecht's internal DSMB. I also act as a methodology assessor (seconded) for the Dutch Medicines Evaluation Board (College ter Beoordeling van Geneesmiddelen: CBG-MEB).
From July 2009 until April 2021 I worked at the Amsterdam UMC location VUmc as a researcher, a statistical consultant and methodology member of the hospital's institutional review board (METc).
I hold a PhD degree in Statistics from Eindhoven University of Technology (2007), a M.A. degree in Health Psychology from Tilburg University (2003) and a M.Sc. degree in Engineering Mathematics from Eindhoven University of Technology (2001). I have held postdoctoral research positions at the Southampton Statistical Sciences Research Institute S3RI (2007-2008) and TNO Quality of Life (2008-2009).
Research aim
Our mission is to drive impactful innovation for cancer prevention, diagnosis, prognosis, treatment, and care through interdisciplinary research, fostering collaboration among researchers across disciplines within the Julius Center and beyond.Research aim
We develop, evaluate, and apply innovative clinical trial designs and sound statistical methodology to efficiently obtain high-quality evidence on healthcare interventions, ultimately optimizing patient outcomesMember of review committees Development (since January 2022) and PIPELINE (since April 2024) - Reviewer of grant applications submitted to Dutch Cancer Society (KWF) - KWF
Expert statistical reviewer - Performing statistical reviews of manuscripts submitted to Diabetologia journal - Diabetologia
Methodology assessor - Assessing dossiers filed for marketing authorization application and providing scientific advice - Dutch Medicines Evaluation Board (CBG-MEB)