Profile photo Gerard Pasterkamp

Gerard Pasterkamp

Full Professor

Strategic program(s):

Biography

Gerard Pasterkamp, MD, is professor Experimental Cardiology and quarter maker of the Circulatory Health Research Center, UMC Utrecht. His research interests are in the field of cardiovascular biology and more specifically innovation in biomarkers. His research interests are in the field of cardiovascular biology and innovation in biomarkers and drug targets. The research group houses the largest atherosclerotic plaque biobank worldwide: Athero Express including >4000 patients. This biobank has generated new insights into determinants of plaque destabilisation. The laboratory also invests in the excavation of genetic determinants of atherosclerotic plaque characteristics. He coordinates national and EU based consortia with the aim to unravel biomarkers and mechanisms of atherosclerotic disease. His translational profile is noted in the private public consortia he is involved in. He is supervising three public private grants that have been rewarded with the aim to develop novel biomarkers and imaging technology to detect cardiac ischemia and endothelial dysfunction. In 2018 he obtained a LeDucq grant together with Prof G Owens (Virginia University) on the role of smooth muscle cell plasticity in the atherosclerotic plaque. 

Recent publications

Computational Modeling Predicts Benefits of Proefferocytic Therapy in Human Atherosclerosis Kai-Uwe Jarr, Kaylin C A Palm, Gerard Pasterkamp, Michal Mokry, Nicholas J Leeper
Circulation, 2025, vol. 152, p.208-211
Genetically determined ancestry associates with morphological and molecular carotid plaque features Nima Fahim, Tim R Sakkers, Joost Hoekstra, Dominique P V de Kleijn, Michal Mokry, Jose Verdezoto Mosquera, Gerard Pasterkamp, Hester M den Ruijter, Clint L Miller, Jessica van Setten, Sander W van der Laan
2025
A Comparative Proteomics Study of Autopsy and Fresh-Frozen Coronary Artery Samples Xiaoke Yin PhD, Alicia Beele MSc, Konstantinos Theofilatos PhD, Ferheen Baig PhD, Maria Hasman PhD, Lukas E Schmidt MSc, Joseph J Boyle PhD, Adam W Turner PhD, Clint L Miller PhD, Gerard Pasterkamp Md, Stefan Stojkovic Md PhD, Johann Wojta PhD, Michael Joner Md, Manuel Mayr Md PhD
Journal of Proteome Research, 2025, vol. 24, p.3154-3159
Plaque erosion Gerard Pasterkamp, Hester M den Ruijter, Michal Mokry
European heart journal, 2025, vol. 46, p.2220-2222
Disturbed Flow Induces Reprogramming of Endothelial Cells to Immune-like and Foam Cells under Hypercholesterolemia during Atherogenesis Christian Park, Kyung In Baek, Ruei-Chun Hung, Leandro Choi, Kiyoung Jeong, Paul Kim, Andrew Keunho Jahng, Jung Hyun Kim, Mostafa Meselhe, Ashwin Kannan, Chien-Ling Chou, Dong Won Kang, Eun Ju Song, Yerin Kim, Jay Aaron Bowman-Kirigin, Michael David Clark, Sander W van der Laan, Gerard Pasterkamp, Nicolas Villa-Roel, Alyssa Panitch, Hanjoong Jo
2025
Intraplaque haemorrhage quantification and molecular characterisation using attention based multiple instance learning Francesco Cisternino, Yipei Song, Tim S Peters, Roderick Westerman, Gert J de Borst, Ernest Diez Benavente, Noortje A M van den Dungen, Petra H van der Kraak, Dominique De Kleijn, Joost M Mekke, Michal Mokry, Gerard Pasterkamp, Hester M den Ruijter, Evelyn Velema, Clint L Miller, Craig A Glastonbury, Sander W van der Laan
2025

External positions

reviewerspanel/commissie Health Holland ronde oktober 2024 - reviewen en met commissie belsuiten over honorering aanvragen - Health Holland

auteur - uitgeven van een boek, maar aantal uren is niet (meer) van toepassing. werk is al gedaan - persoonlijk, geen werkgever

Voorzitter Wetenschappelijke Adviesraad - Voorzitten vergaderingen - Reuma Nederland