Natalia Smith Cortinez

Assistant Professor

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Research groups

Neuro otology

Research aim

We aim to improve the quality of life of patients with sensorineural hearing loss, by a multidisciplinary approach targetting hair cell and spiral ganglion neuron survival and regeneration, prevention approaches, and improving surgical techniques.

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Recent publications

Long-term survival of LGR5 expressing supporting cells after severe ototoxic trauma in the adult mouse cochlea Natalia Smith-Cortinez, Ferry G J Hendriksen, Dyan Ramekers, Robert J Stokroos, Huib Versnel, Louise V Straatman
Frontiers in Cellular Neuroscience, 2023, vol. 17
Regeneration of Hair Cells from Endogenous Otic Progenitors in the Adult Mammalian Cochlea Natalia Smith-Cortinez, A Katherine Tan, Robert J Stokroos, Huib Versnel, Louise V Straatman
International Journal of Molecular Sciences, 2023, vol. 24, p.1-23
LGR5-Positive Supporting Cells Survive Ototoxic Trauma in the Adult Mouse Cochlea Natalia Smith-Cortinez, Rana Yadak, Ferry G J Hendriksen, Eefje Sanders, Dyan Ramekers, Robert J Stokroos, Huib Versnel, Louise V Straatman
Frontiers in Molecular Neuroscience, 2021, vol. 14, p.1-9
Collagen release by human hepatic stellate cells requires vitamin C and is efficiently blocked by hydroxylase inhibition Natalia Smith-Cortinez, Raphael R Fagundes, Valentina Gomez, Defu Kong, Dirk R de Waart, Janette Heegsma, Svenja Sydor, Peter Olinga, Vincent E de Meijer, Cormac T Taylor, Ruud Bank, Coen C Paulusma, Klaas Nico Faber
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021, vol. 35, p.e21219
Simultaneous Induction of Glycolysis and Oxidative Phosphorylation during Activation of Hepatic Stellate Cells Reveals Novel Mitochondrial Targets to Treat Liver Fibrosis Natalia Smith-Cortinez, Karen van Eunen, Janette Heegsma, Sandra Alejandra Serna-Salas, Svenja Sydor, Lars P Bechmann, Han Moshage, Barbara M Bakker, Klaas Nico Faber
Cells, 2020, vol. 9, p.1-15