Research groups

Utrecht Osteoarthritis Research - UROAR

Research aim

Our group studies osteoarthritis, from disease mechanisms to treatment strategies. Using a translational approach, we connect lab research to patient care, aiming to create effective diagnostic tools and patient-centered therapies.

Go to group

Recent publications

Machine-learning predicted and actual 2-year structural progression in the IMI-APPROACH cohort Mylène P. Jansen, Wolfgang Wirth, Jaume Bacardit, Eefje M. van Helvoort, Anne C.A. Marijnissen, Margreet Kloppenburg, Francisco J. Blanco, Ida K. Haugen, Francis Berenbaum, Cristoph H. Ladel, Marieke Loef, Floris P.J.G. Lafeber, Paco M. Welsing, Simon C. Mastbergen, Frank W. Roemer
Quantitative Imaging in Medicine and Surgery, 2023, vol. 13, p.3298-3306
Structural changes after ankle joint distraction in haemophilic arthropathy Eline D P van Bergen, Simon C Mastbergen, Floris P J G Lafeber, Anne-Christine Bay-Jensen, Sofie F Madsen, Helena Port, Wouter Foppen, Roger E G Schutgens, Mylène P Jansen, Lize F D van Vulpen
Haemophilia, 2023, vol. 29, p.874-882
Identifying multivariate disease trajectories and potential phenotypes of early knee osteoarthritis in the CHECK cohort Sara Altamirano, Mylène P. Jansen, Daniel L. Oberski, Marinus J.C. Eijkemans, Simon C. Mastbergen, Floris P.J.G. Lafeber, Willem E. van Spil, Paco M.J. Welsing
PLoS ONE, 2023, vol. 18
MRI-based synthetic CT in the detection of knee osteoarthritis Saeed Arbabi, Wouter Foppen, Willem Paul Gielis, Marijn van Stralen, Mylène Jansen, Vahid Arbabi, Pim A de Jong, Harrie Weinans, Peter Seevinck
Journal of Orthopaedic Research, 2023, vol. 41, p.2530-2539
Magnetic resonance imaging-based bone imaging of the lower limb Mateusz C Florkow, Chien H Nguyen, Ralph J B Sakkers, Harrie Weinans, Mylene P Jansen, Roel J H Custers, Marijn van Stralen, Peter R Seevinck
Journal of Orthopaedic Research, 2023, vol. 42, p.843-854
Exploring the differences between radiographic joint space width and MRI cartilage thickness changes using data from the IMI-APPROACH cohort Mylène P. Jansen, Frank W. Roemer, Anne Karien C.A. Marijnissen, Margreet Kloppenburg, Francisco J. Blanco, Ida K. Haugen, Francis Berenbaum, Floris P.J.G. Lafeber, Paco M.J. Welsing, Simon C. Mastbergen, Wolfgang Wirth
Skeletal Radiology, 2023, vol. 52, p.1339-1348