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Marien Houtman

Research Analyst

Contact

mhoutman@umcutrecht.nl
Pure profile

Recent publications

All publications
Development of new Kir2.1 channel openers from propafenone analogues Encan Li, Najla Boujeddaine, Marien J.C. Houtman, Renee G.C. Maas, Joost P.G. Sluijter, Gerhard F. Ecker, Anna Stary-Weinzinger, Willem B. van Ham, Marcel A.G. van der Heyden
British Journal of Pharmacology, 2024, vol. 182, p.633-650
Development of IKATP Ion Channel Blockers Targeting Sulfonylurea Resistant Mutant KIR6.2 Based Channels for Treating DEND Syndrome Marien J C Houtman, Theres Friesacher, Xingyu Chen, Eva-Maria Zangerl-Plessl, Marcel A G van der Heyden, Anna Stary-Weinzinger
Frontiers in Pharmacology, 2022, vol. 12, p.1-15
PI3K/mTOR inhibitor omipalisib prolongs cardiac repolarization along with a mild proarrhythmic outcome in the AV block dog model J. J.A. van Bavel, C. Pham, H. D.M. Beekman, M. J.C. Houtman, A. Bossu, R. W. Sparidans, M. A.G. van der Heyden, M. A. Vos
Frontiers in cardiovascular medicine, 2022, vol. 9
Determing the role of uremic toxins on cardiac electrophysiology and pro-arrhythmia during chronic kidney disease WB van Ham, Alexandre Bossu, Marien Houtman, Carlijn M Cornelissen, MA Vos, TAB van Veen
Europace, 2022, vol. 24
Selective late sodium current inhibitor GS-458967 suppresses Torsades de Pointes by mostly affecting perpetuation but not initiation of the arrhythmia Alexandre Bossu, Marien J.C. Houtman, Veronique M.F. Meijborg, Rosanne Varkevisser, Henriette D.M. Beekman, Albert Dunnink, Jacques M.T. de Bakker, Nevena Mollova, Sridharan Rajamani, Luiz Belardinelli, Marcel A.G. van der Heyden, Marc A. Vos
British Journal of Pharmacology, 2018, vol. 175, p.2470-2482
Insights in KIR2.1 channel structure and function by an evolutionary approach; cloning and functional characterization of the first reptilian inward rectifier channel KIR2.1, derived from the California kingsnake (Lampropeltis getula californiae) M.J.C. Houtman, S. Korte, Y. JI, G.J.M. Kok, M.A. Vos, A. Stary-Weinzinger, M.A.G. van der Heyden
Biochemical and Biophysical Research Communications, 2014, vol. 452, p.992-997