Marien Houtman

Research Analyst

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Recent publications

Arrhythmia Inducibility in the CAVB Dog Model, A Critical Analysis on Underlying Factors Joanne J A van Bavel, Henriëtte D M Beekman, Marien J C Houtman, Marc A Vos, Marcel A G van der Heyden
Cardiovascular Toxicology, 2025, vol. 25, p.1344-1351

Development of new K_ir2.1 channel openers from propafenone analogues Encan Li, Najla Boujeddaine, Marien J.C. Houtman, Renee G.C. Maas, Joost P.G. Sluijter, Gerhard F. Ecker, Anna Stary-Weinzinger, Willem B. van Ham, Marcel A.G. van der Heyden
British Journal of Pharmacology, 2024, vol. 182, p.633-650

Development of IKATP Ion Channel Blockers Targeting Sulfonylurea Resistant Mutant KIR6.2 Based Channels for Treating DEND Syndrome Marien J C Houtman, Theres Friesacher, Xingyu Chen, Eva-Maria Zangerl-Plessl, Marcel A G van der Heyden, Anna Stary-Weinzinger
Frontiers in Pharmacology, 2022, vol. 12, p.1-15

PI3K/mTOR inhibitor omipalisib prolongs cardiac repolarization along with a mild proarrhythmic outcome in the AV block dog model J. J.A. van Bavel, C. Pham, H. D.M. Beekman, M. J.C. Houtman, A. Bossu, R. W. Sparidans, M. A.G. van der Heyden, M. A. Vos
Frontiers in cardiovascular medicine, 2022, vol. 9

Determing the role of uremic toxins on cardiac electrophysiology and pro-arrhythmia during chronic kidney disease WB van Ham, Alexandre Bossu, Marien Houtman, Carlijn M Cornelissen, MA Vos, TAB van Veen
Europace, 2022, vol. 24

Selective late sodium current inhibitor GS-458967 suppresses Torsades de Pointes by mostly affecting perpetuation but not initiation of the arrhythmia Alexandre Bossu, Marien J.C. Houtman, Veronique M.F. Meijborg, Rosanne Varkevisser, Henriette D.M. Beekman, Albert Dunnink, Jacques M.T. de Bakker, Nevena Mollova, Sridharan Rajamani, Luiz Belardinelli, Marcel A.G. van der Heyden, Marc A. Vos
British Journal of Pharmacology, 2018, vol. 175, p.2470-2482