Maria Rodriguez Colman

Associate Professor

Strategic program(s):

Contact

mrodrigu@umcutrecht.nl

Pure profile

Research groups

Metabolism, Stem cells and Cancer

Research aim

Our overarching goal is to gain deep molecular understanding of cancer and stem cell metabolism to enable the development of novel therapies to treat diseases with a particular interest in cancer.

Go to group

Recent publications

All publications

Signaling switches María J Rodríguez Colman, Katharina F Sonnen
Cell stem cell, 2025, vol. 32, p.673-675

Growth of the maternal intestine during reproduction Tomotsune Ameku, Anna Laddach, Hannah Beckwith, Alexandra Milona, Loranzie S Rogers, Cornelia Schwayer, Emma Nye, Iain R Tough, Jean-Louis Thoumas, Umesh Kumar Gautam, Yi-Fang Wang, Shreya Jha, Alvaro Castano-Medina, Christopher Amourda, Patric M Vaelli, Sira Gevers, Elaine E Irvine, Leah Meyer, Ivan Andrew, Ka Lok Choi, Bhavik Patel, Alice J Francis, Chris Studd, Laurence Game, George Young, Kevin G Murphy, Bryn Owen, Dominic J Withers, Maria Rodriguez-Colman, Helen M Cox, Prisca Liberali, Martin Schwarzer, François Leulier, Vassilis Pachnis, Nicholas W Bellono, Irene Miguel-Aliaga
Cell, 2025, vol. 188, p.2738-2756.e22

Lactate controls cancer stemness and plasticity through epigenetic regulation Nguyen T B Nguyen, Sira Gevers, Rutger N U Kok, Lotte M Burgering, Hannah Neikes, Ninouk Akkerman, Max A Betjes, Marlies C Ludikhuize, Can Gulersonmez, Edwin C A Stigter, Yvonne Vercoulen, Jarno Drost, Hans Clevers, Michiel Vermeulen, Jeroen S van Zon, Sander J Tans, Boudewijn M T Burgering, Maria J Rodríguez Colman
Cell Metabolism, 2025, vol. 37, p.903-919.e10

NAC regulates metabolism and cell fate in intestinal stem cells Sofia Ramalho, Ferhat Alkan, Stefan Prekovic, Katarzyna Jastrzebski, Eric Pintó Barberà, Liesbeth Hoekman, Maarten Altelaar, Cecilia de Heus, Nalan Liv, Maria J. Rodríguez-Colman, Mehmet Yilmaz, Rob van der Kammen, Juliette Fedry, Mark C. de Gooijer, Saskia Jacoba Elisabeth Suijkerbuijk, William J. Faller, Joana Silva
Science advances, 2025, vol. 11, p.eadn9750

FOXO transcription factors as mediators of stress adaptation Maria J. Rodriguez-Colman, Tobias B. Dansen, Boudewijn M.T. Burgering
Nature reviews molecular cell biology, 2024, vol. 25, p.46-64

Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis Delilah Hendriks, Jos F. Brouwers, Karien Hamer, Maarten H. Geurts, Léa Luciana, Simone Massalini, Carmen López-Iglesias, Peter J. Peters, Maria J. Rodríguez-Colman, Susana Chuva de Sousa Lopes, Benedetta Artegiani, Hans Clevers
Nature Biotechnology, 2023, vol. 41, p.1567-1581