Profile photo Magdalena Lorenowicz

Magdalena Lorenowicz

Assistant Professor

Strategic program(s):

Biography

 Magdalena Lorenowicz studied Biotechnology at the Jagiellonian University in Kraków. In September 2001 she moved to Amsterdam to start her Ph.D. research. During her Ph.D. studies she investigated the role of cAMP signalling in the regulation of leukocyte chemotaxis and endothelial barrier function. After completion of her thesis, Magdalena moved to the Hubrecht Institute in Utrecht, where supported by prestigious VENI award (2008) she focused on the mechanism of Wnt secretion, combining the genetics of C. elegans with cutting edge cell biology techniques in mammalian cells. In April 2012 she joined the Department of Cell Biology and Center for Molecular Medicine at Universty Medical Center Utrecht to set up her own research line investigating molecular mechanisms regulating the immunosuppressive and regenerative properties of the human mesenchymal stem/stromal cells (MSC) with the ultimate goal to directly link her expertise in studying cell-cell communication with clinical applications. Since 2015 she works as independent research fellow at Regenerative Medicine Center Utrecht. Here she expanded her research group and works on the interphase of fundamental research and regenerative medicine and continues to investigate biology of MSC and their in vivo function with the final goal to improve MSC-based therapies.

Personal website:

http://www.msc-biology-group.com

Strategic program(s):

Contact

Recent publications

Minimal information for studies of extracellular vesicles (MISEV2023) Joshua A. Welsh, Deborah C.I. Goberdhan, Lorraine O’Driscoll, Edit I. Buzas, Cherie Blenkiron, Benedetta Bussolati, Houjian Cai, Dolores Di Vizio, Tom A.P. Driedonks, Uta Erdbrügger, Juan M. Falcon-Perez, Qing Ling Fu, Andrew F. Hill, Metka Lenassi, Sai Kiang Lim, G. Mahoney M˜y, Sujata Mohanty, Andreas Möller, Rienk Nieuwland, Takahiro Ochiya, Susmita Sahoo, Ana C. Torrecilhas, Lei Zheng, Andries Zijlstra, Sarah Abuelreich, Reem Bagabas, Paolo Bergese, Esther M. Bridges, Marco Brucale, Dylan Burger, Randy P. Carney, Emanuele Cocucci, Rossella Crescitelli, Edveena Hanser, Adrian L. Harris, Norman J. Haughey, An Hendrix, Alexander R. Ivanov, Tijana Jovanovic-Talisman, Nicole A. Kruh-Garcia, Bas W.M. van Balkom, Federica Collino, Olivier G. de Jong, Sander A.A. Kooijmans, Magdalena J. Lorenowicz, Kenny Man, Marieke T. Roefs, Raymond M. Schiffelers, Joost P.G. Sluijter, Pieter Vader,
Journal of Extracellular Vesicles, 2024, vol. 13
Injectable hydrogels for sustained delivery of extracellular vesicles in cartilage regeneration Sanne M. van de Looij, Olivier G. de Jong, Tina Vermonden, Magdalena J. Lorenowicz
Journal of Controlled Release, 2023, vol. 355, p.685-708
Mesenchymal stem/stromal cells-derived extracellular vesicles as a potentially more beneficial therapeutic strategy than MSC-based treatment in a mild metabolic osteoarthritis model Kelly Warmink, Jaqueline L. Rios, Suzy Varderidou-Minasian, Marta Torres-Torrillas, Devin R. van Valkengoed, Sabine Versteeg, Niels Eijkelkamp, Harrie Weinans, Nicoline M. Korthagen, Magdalena J. Lorenowicz
Stem Cell Research and Therapy, 2023, vol. 14
A kaleidoscopic view of extracellular vesicles in lysosomal storage disorders Charlotte V. Hegeman, Olivier G. de Jong, Magdalena J. Lorenowicz
Extracellular Vesicles and Circulating Nucleic Acids, 2022, vol. 3, p.393-421
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, Marie H Abildgaard, Yakubu Princely Abudu, Abraham Acevedo-Arozena, Iannis E Adamopoulos, Khosrow Adeli, Timon E Adolph, Annagrazia Adornetto, Elma Aflaki, Galila Agam, Anupam Agarwal, Bharat B Aggarwal, Maria Agnello, Patrizia Agostinis, Javed N Agrewala, Alexander Agrotis, Patricia V Aguilar, S Tariq Ahmad, Zubair M Ahmed, Ulises Ahumada-Castro, Sonja Aits, Shu Aizawa, Yunus Akkoc, Tonia Akoumianaki, Hafize Aysin Akpinar, Ahmed M Al-Abd, Lina Al-Akra, Abeer Al-Gharaibeh, Moulay A Alaoui-Jamali, Simon Alberti, Elísabet Alcocer-Gómez, Cristiano Alessandri, Muhammad Ali, M Abdul Alim Al-Bari, Saeb Aliwaini, Javad Alizadeh, Eugènia Almacellas, Alexandru Almasan, Alicia Alonso, Magdalena J Lorenowicz, Claudia Manzoni, Fulvio Reggiori, Jorg van Loosdregt, Yan Wang,
Autophagy, 2021, vol. 17, p.1-382
Mesenchymal stromal/stem cell-derived extracellular vesicles in tissue repair: challenges and opportunities Suzy Varderidou-Minasian, Magdalena J. Lorenowicz
Theranostics, 2020, vol. 10, p.5979-5997