Profile photo Maarten van Smeden

Maarten van Smeden

Associate Professor

Strategic program(s):

Biography

Maarten van Smeden is a medical statistician, associate professor of epidemiologic methods and head of the research program methodology at the Julius Center for Health Sciences and Primary Care, UMC Utrecht, the Netherlands. His research is focused on the development and evaluation of statistical and data science methodology, with a particular focus on methodology related to the development, validation and implementation of prediction models. 

Research groups

Methods for AI and data science

Research aim

To develop and validate methods for data science, AI, statistics and causal inference and to improve medical research and patient care through impactful applications and collaborations.

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Recent publications

Evaluation of performance measures in predictive artificial intelligence models to support medical decisions Ben Van Calster, Gary S. Collins, Andrew J. Vickers, Laure Wynants, Kathleen F. Kerr, Lasai Barreñada, Gael Varoquaux, Karandeep Singh, Karel Gm Moons, Tina Hernandez-Boussard, Dirk Timmerman, David J. McLernon, Maarten van Smeden, Ewout W. Steyerberg,
The Lancet. Digital health, 2025, vol. 7
Explainable AI in healthcare Alex Carriero, Anne de Hond, Bram Cappers, Fernando Paulovich, Sanne Abeln, Karel Gm Moons, Maarten van Smeden
Diagnostic and Prognostic Research, 2025, vol. 9
In humble defence of unexplainable black box prediction models in healthcare Florien S van Royen, Hilde J P Weerts, Anne A H de Hond, Geert-Jan Geersing, Frans H Rutten, Karel G M Moons, Maarten van Smeden
Journal of Clinical Epidemiology, 2025, vol. 189
Extended sample size calculations for evaluation of prediction models using a threshold for classification Rebecca Whittle, Joie Ensor, Lucinda Archer, Gary S. Collins, Paula Dhiman, Alastair Denniston, Joseph Alderman, Amardeep Legha, Maarten van Smeden, Karel G. Moons, Jean Baptiste Cazier, Richard D. Riley, Kym I.E. Snell
BMC Medical Research Methodology, 2025, vol. 25
Is frailty incremental to the 4C Mortality model for mortality risk prediction in hospitalized older individuals with COVID-19 disease? Anum Zahra, Bas F M van Raaij, Maarten van Smeden, Rishi K Gupta, Jacobijn Gussekloo, Kim Luijken, Karel G M Moons, Simon P Mooijaart, Raymond Noordam, Anne A H de Hond,
Journal of Clinical Epidemiology, 2025, vol. 185
Importance of sample size on the quality and utility of AI-based prediction models for healthcare Richard D. Riley, Joie Ensor, Kym I.E. Snell, Lucinda Archer, Rebecca Whittle, Paula Dhiman, Joseph Alderman, Xiaoxuan Liu, Laura Kirton, Jay Manson-Whitton, Maarten van Smeden, Karel G. Moons, Krishnarajah Nirantharakumar, Jean Baptiste Cazier, Alastair K. Denniston, Ben Van Calster, Gary S. Collins
The Lancet Digital Health, 2025, vol. 7