Ludo van der Pol

Full Professor

Strategic program(s):

Contact

wpol2@umcutrecht.nl

Pure profile

Research groups

Research in Spinal Muscular Atrophy

Research aim

The Netherlands SMA Center is the single dedicated center for SMA in the Netherlands, including newborn screening, diagnostics, care, treatments and scientific research. We conduct various national and internal clinical trials and studies.

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Recent publications

All publications

Motor Unit Patterns Correlate With Severity in Symptomatic Patients With Spinal Muscular Atrophy Leandra A A Ros, W Ludo van der Pol, Diederik J L Stikvoort García, H Stephan Goedee, Hessel Franssen, Fay-Lynn Asselman, Bart Bartels, Danny R van der Woude, Ruben P A van Eijk, Boudewijn T H M Sleutjes, Renske I Wadman
European Journal of Neurology, 2025, vol. 32

Course of joint range of motion in children with spinal muscular atrophy receiving disease-modifying treatment I L B Oude Lansink, J W Gorter, W L van der Pol, D R Vd Woude, P J Scheiberlich, R P A van Eijk, B Bartels, A Beelen
Orphanet Journal of Rare Diseases, 2025, vol. 20

Safety and efficacy of apitegromab in nonambulatory type 2 or type 3 spinal muscular atrophy (SAPPHIRE) Thomas O Crawford, Laurent Servais, Eugenio Mercuri, Heike Kölbel, Nancy Kuntz, Richard S Finkel, Jena Krueger, Kaitlin Batley, Sally Dunaway Young, Jing L Marantz, Guochen Song, Bert Yao, Guolin Zhao, Jose Rossello, Giridhar S Tirucherai, Elena Stacy Mazzone, Russell J Butterfield, Marta Gomez Garcia de la Banda, Andreea M Seferian, Valeria A Sansone, Liesbeth De Waele, W Ludo van der Pol, Claude Cances, Astrid Pechmann, Basil T Darras,
The Lancet. Neurology, 2025, vol. 24, p.727-739

Further Comments on Risdiplam for Prenatal Therapy of Spinal Muscular Atrophy Renske I Wadman, Ewout J N Groen, W Ludo van der Pol
The New England journal of medicine, 2025, vol. 393

Comprehensive analysis across SMN2 excludes DNA methylation as an epigenetic biomarker for spinal muscular atrophy Maria M. Zwartkruis, Joris V. Kortooms, Demi Gommers, Martin G. Elferink, Ilaria Signoria, Joyce van der Sel, Paul J. Hop, Ramona A.J. Zwamborn, Robin Geene, Jared W. Green, Hanneke W.M. van Deutekom, Wouter van Rheenen, Jan H. Veldink, Fay Lynn Asselman, Renske I. Wadman, W. Ludo van der Pol, Gijs W. van Haaften, Ewout J.N. Groen
iScience, 2025, vol. 28

A de novo deletion underlying spinal muscular atrophy Maria M Zwartkruis, Mirjam S de Pagter, Demi Gommers, Marije Koopmans, Cecile P E Ottenheim, Joris V Kortooms, Mirjan Albring, Martin G Elferink, Renske I Wadman, Fay-Lynn Asselman, Inge Cuppen, W Ludo van der Pol, Marcel R Nelen, Gijs W van Haaften, Ewout J N Groen
Human molecular genetics, 2025, vol. 34, p.894–904

External positions

Bestuurslid - zie bijlage - Spierziekten Centrum Nederland