Lucas Kaaij

Assistant Professor

Strategic program(s):

Contact

lkaaij2@umcutrecht.nl

Pure profile

Research groups

Genome and chromatin organization

Research aim

Our research focusses on understanding how cells with the same genetic material can give rise to a multicellular organism containing numerous different cell types with highly specific functions.

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Recent publications

All publications

Correction to Julia S. Scott, Loubna Al Ayadi, Emmanouela Epeslidou, Roan H. van Scheppingen, Anna Mukha, Lucas J.T. Kaaij, Catrin Lutz, Stefan Prekovic
Oncogene, 2025, vol. 44, p.2561–2562

Emerging roles of cohesin-STAG2 in cancer Julia S. Scott, Loubna Al Ayadi, Emmanouela Epeslidou, Roan H. van Scheppingen, Anna Mukha, Lucas J.T. Kaaij, Catrin Lutz, Stefan Prekovic
Oncogene, 2024, vol. 44, p.277–287

guidedNOMe-seq quantifies chromatin states at single allele resolution for hundreds of custom regions in parallel Michaela Schwaiger, Fabio Mohn, Marc Bühler, Lucas J.T. Kaaij
BMC Genomics, 2024, vol. 25

ChAHP2 and ChAHP control diverse retrotransposons by complementary activities Josip Ahel, Aparna Pandey, Michaela Schwaiger, Fabio Mohn, Anja Basters, Georg Kempf, Aude Andriollo, Lucas Kaaij, Daniel Hess, Marc Bühler
Genes and Development, 2024, vol. 38, p.554-568

The ChAHP Complex Counteracts Chromatin Looping at CTCF Sites that Emerged from SINE Expansions in Mouse Lucas J T Kaaij, Fabio Mohn, Robin H van der Weide, Elzo de Wit, Marc Bühler
Cell, 2019, vol. 178, p.1437-1451.e14

Systemic Loss and Gain of Chromatin Architecture throughout Zebrafish Development Lucas J T Kaaij, Robin H van der Weide, René F Ketting, Elzo de Wit
Cell Reports, 2018, vol. 24, p.1-10.e4