Lotty Hooft

Full Professor

Biography

Prof. Dr. Lotty Hooft is Professor of Evidence Synthesis and Knowledge Translation in Healthcare at the Julius Center, UMC Utrecht, and Director of Cochrane Netherlands. She heads the Department of Epidemiology and Health Economics and the international MSc in Epidemiology program. With more than two decades of experience, she is an internationally recognized expert in systematic reviews, diagnostic and prognostic test evaluation, and guideline development, and has helped shape key reporting and risk-of-bias standards including TRIPOD, STARD, and PROBAST, as well as the (de)implementation of evidence-based healthcare practices.

Contact

lhooft@umcutrecht.nl

Pure profile

Recent publications

All publications

Agreement testing of AMSTAR-PF, a tool for quality appraisal of systematic reviews of prognostic factor studies Michael L Henry, Neil E O'Connell, Richard D Riley, Karel G M Moons, Beverley J Shea, Lotty Hooft, Sarah B Wallwork, Johanna A A G Damen, Nicole Skoetz, Ruth P Appiah, Carolyn Berryman, Sophie M Crouch, Grace A Ferencz, Ashley R Grant, Katherine M Henry, Aleksandra M Herman, Emma L Karran, Indika Koralegedera, Hayley B Leake, Erin MacIntyre, Brendan Mouatt, Karma Phuentsho, Daniel A Van Der Laan, Ellana Welsby, Louise K Wiles, Erica M Wilkinson, Marelle K Wilson, Monique V Wilson, G Lorimer Moseley
BMJ Open, 2026, vol. 16

Diagnostic tests for autism spectrum disorder (ASD) in preschool children Amanda Brignell, Kris Chan, Tayla Chellew, Chathuri Vihanga Maddumahewa, Nicole Wong, Lotty Hooft, Mohammed Alshawsh, Katrina Williams
The Cochrane database of systematic reviews, 2026, vol. 1

Prediction models developed using artificial intelligence Maerziya Yusufujiang, Constanza L Andaur Navarro, Johanna Aa Damen, Toshihiko Takada, Geert-Jan Geersing, Lotty Hooft, Ewoud Schuit, Karel Gm Moons, Valentijn Mt de Jong, Maarten van Smeden
Diagnostic and Prognostic Research, 2026, vol. 10

Comparative Efficacy of all Available Pharmaceutical Therapies for Moderate to Severe Crohn's Disease Matthijs Versteegh, Demy L. Idema, Simone Huygens, Kevin Jenniskens, Marieke Pierik, Tessa Römkens, Fiona van Schaik, Peter Wahab, Linde F. Huis in't Veld, Mike Kusters, Kim van der Braak, Lotty Hooft, Johanna A.A. Damen
Gastro Hep Advances, 2026, vol. 5

Amstar-pf Michael L Henry, Neil E O'Connell, Richard D Riley, Karel G M Moons, Beverley J Shea, Lotty Hooft, Johanna A A Damen, Nicole Skoetz, Sarah B Wallwork, G Lorimer Moseley
BMJ (Clinical research ed.), 2025, vol. 391

Write Your Abstracts Carefully - The Impact of Abstract Reporting Quality on Findability by Semi-Automated Title-Abstract Screening Tools I Spiero, A M Leeuwenberg, K G M Moons, L Hooft, J A A Damen
Journal of Clinical Epidemiology, 2025, vol. 188

External positions

Lid ZEGG evaluatiecommissie (Zorg Evaluatie en Gepast Gebruik) - Evaluatie van ZEGG aanvragen vanuit UMC perspectief - ZonMW/ZIN

Lid Wetenschappelijke Adviesraad (WAR) Care & Cure - Adviseren en beoordelen van duidingsrapporten - Zorginstituut Nederland

Lid van onafhankelijke adviescommissie - Toetsen van projectideeën en uitgewerkte subsidieaanvragen voor de subsidieregeling (Advenzo) - Zorginstituut

Alternate membership Veelbelovende Zorg - Adviseren over methodologie in co-creaties - ZonMW/ZIN

Member Steering Group Scientific Committee ICTRP (WHO) - Wetenschappelijke koers voor internationale trial-registratie en datatransparantie mede vormgeven - WHO

WHO Essential Diagnostic List (EDL) Evidence Submission Methodological Reviewer - Toetsen van de methodologisch de bewijsvoering voor de wereldwijde lijst van essentiële diagnostiek - WHO

Member Editorial Board Journal for Diagnostic and Prognostic Research. - Redacteurschap om de wetenschappelijke kwaliteit van publicaties te bewaken - Journal for Diagnostic and Prognostic Research

Member Council and Methods Groups (Prognosis, Screening and Diagnostic Tests) - Methodology development - Cochrane

Member WHO International Clinical Trial Registry Platform (ICTRP) Scientific Advisory Group. - Adviesrol die wereldwijd bijdraagt aan de transparantie en registratie van klinische onderzoek - WHO