Lodewijk Brosens

Associate Professor - medical

Strategic program(s):

Biography

2015-present: Associate professor of pathology, gastrointestinal and endocrine pathology, UMC Utrecht.

2014-2015: Post-doctoral research fellow department of pathology Johns Hopkins Hospital, Baltimore

2013: Pathologist, gastrointestinal pathology, Academic Medical Center Amsterdam

2008-2013: Pathology residency

2008: PhD, Gastrointestinal polyposis syndromes, clinical and molecular aspects of Familial Adenomatous Polyposis en Juvenile Polyposis, Utrecht University

2006: M.D. University of Amsterdam

2004: MSc. Biomedical Science, Vrije Universiteit, Amsterdam

2003-2004: Research fellow Departments of Pathology and Gastroenterology, Johns Hopkins Hospital, Baltimore

Strategic program(s):

Contact

lbrosens@umcutrecht.nl

Pure profile

Research groups

Pathology of gastrointestinal tract tumors

Research aim

Our aim is to increase understanding of the pathogenesis of gastrointestinal tract tumors and to identify and validate potential histopathological and molecular biomarkers to improve and personalize therapy for patients.

Go to group

Endocrine oncology research group

Research aim

To improve diagnostics, treatment and outcome for children and adults with Rare Endocrine Tumors by interdisciplinary and international collaborative research.

Go to group

Recent publications

All publications

DNA Methylation Profiling Enables Accurate Classification of Nonductal Primary Pancreatic Neoplasms Anna Vera D. Verschuur, Wenzel M. Hackeng, Florine Westerbeke, Jamal K. Benhamida, Olca Basturk, Pier Selenica, G. Mihaela Raicu, I. Quintus Molenaar, Hjalmar C. van Santvoort, Lois A. Daamen, David S. Klimstra, Shinichi Yachida, Claudio Luchini, Aatur D. Singhi, Christoph Geisenberger, Lodewijk A.A. Brosens
Clinical Gastroenterology and Hepatology, 2024, vol. 22, p.1245-1254.e10

Histology-Based Radiomics for [ 18F]FDG PET Identifies Tissue Heterogeneity in Pancreatic Cancer. Esther M M Smeets, Marija Trajkovic-Arsic, Daan Geijs, Sinan Karakaya, Monica van Zanten, Lodewijk A A Brosens, Benedikt Feuerecker, Martin Gotthardt, Jens T Siveke, Rickmer Braren, Francesco Ciompi, Erik H J G Aarntzen
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2024, vol. 65, p.1151-1159

Correction L. A. Daamen, I. W.J.M. van Goor, V. P. Groot, P. C.M. Andel, L. A.A. Brosens, O. R. Busch, G. A. Cirkel, N. Haj Mohammad, H. D. Heerkens, I. H.J.T. de Hingh, F. Hoogwater, H. W.M. van Laarhoven, M. Los, G. J. Meijer, V. E. de Meijer, R. Pande, K. J. Roberts, J. Stoker, M. W.J. Stommel, G. van Tienhoven, R. C. Verdonk, H. M. Verkooijen, F. J. Wessels, J. W. Wilmink, M. G. Besselink, H. C. van Santvoort, M. P.W. Intven, I. Q. Molenaar,
Trials, 2024, vol. 25

Comprehensive Characterization of Intraductal Oncocytic Papillary Neoplasm of the Pancreas Gaetano Paolino, Olca Basturk, Irene Esposito, Seung-Mo Hong, Lodewijk A Brosens, Zeynep Tarcan, Laura D Wood, Anastasios Gkountakos, Yuko Omori, Paola Mattiolo, Calogero Ciulla, Giovanni Marchegiani, Antonio Pea, Michele Bevere, Riccardo De Robertis, Mirko D'Onofrio, Roberto Salvia, Liang Cheng, Toru Furukawa, Aldo Scarpa, Volkan Adsay, Claudio Luchini
Modern Pathology, 2024, vol. 37

Optimization of ERCP Technique to Improve the Sensitivity of Biliary Brushing Robert C Verdonk, Roeland Zoutendijk, Peter J Van der Schaar, Paul Didden, Hans Kelder, Lodewijk A Brosens, Hjalmar C Van Santvoort, Mihaela G Raicu, Frank Vleggaar
Journal of Gastroenterology and Liver Diseases, 2024, vol. 33, p.254-260

Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancer Hamzeh Kayhanian, William Cross, Suzanne E M van der Horst, Panagiotis Barmpoutis, Eszter Lakatos, Giulio Caravagna, Luis Zapata, Arne Van Hoeck, Sjors Middelkamp, Kevin Litchfield, Christopher Steele, William Waddingham, Dominic Patel, Salvatore Milite, Chen Jin, Ann-Marie Baker, Daniel C Alexander, Khurum Khan, Daniel Hochhauser, Marco Novelli, Benjamin Werner, Ruben van Boxtel, Joris H Hageman, Julian R Buissant des Amorie, Josep Linares, Marjolijn J L Ligtenberg, Iris D Nagtegaal, Miangela M Laclé, Leon M G Moons, Lodewijk A A Brosens, Nischalan Pillay, Andrea Sottoriva, Trevor A Graham, Manuel Rodriguez-Justo, Kai-Keen Shiu, Hugo J G Snippert, Marnix Jansen
Nature Genetics, 2024, vol. 56, p.1420-1433

Fellowships & Awards

2019: Visiting Professor Department of Pathology Verona, Italy

External positions

Patholoog - Gastrointestinal and pancreato-biliary pathology - Radboudumc