Lodewijk Brosens

Associate Professor - medical

Strategic program(s):

Biography

2021-present: Clinical Scientist UMC Utrecht

2015-present: Associate professor of pathology, gastrointestinal and endocrine pathology, UMC Utrecht.

2014-2015: Post-doctoral research fellow department of pathology Johns Hopkins Hospital, Baltimore

2013: Pathologist, gastrointestinal pathology, Academic Medical Center Amsterdam

2008-2013: Pathology residency

2008: PhD, Gastrointestinal polyposis syndromes, clinical and molecular aspects of Familial Adenomatous Polyposis en Juvenile Polyposis, Utrecht University

2006: M.D. University of Amsterdam

2004: MSc. Biomedical Science, Vrije Universiteit, Amsterdam

2003-2004: Research fellow Departments of Pathology and Gastroenterology, Johns Hopkins Hospital, Baltimore

Strategic program(s):

Contact

lbrosens@umcutrecht.nl

Pure profile

Research groups

Pathology of gastrointestinal tract tumors

Research aim

Our aim is to increase understanding of the pathogenesis of gastrointestinal tract tumors and to identify and validate potential histopathological and molecular biomarkers to improve and personalize therapy for patients.

Go to group

Endocrine oncology research group

Research aim

To improve diagnostics, treatment and outcome for children and adults with Rare Endocrine Tumors by interdisciplinary and international collaborative research.

Go to group

Recent publications

All publications

A new link between insulinoma and congenital glucose-galactose malabsorption Antonio Prinzi, Jelka Kuiper, Adorée M van der Wiel, Marie-Louise F van Velthuysen, Remco T P van Cruchten, Lodewijk A A Brosens, Wouter W de Herder, Johannes Hofland
Endocrine oncology (Bristol, England), 2025, vol. 5

Incomplete neoadjuvant chemo(radio)therapy negatively impacts pathological response and overall survival in locally advanced esophageal cancer Denice Kamp, Samuel Noya, Stella Mook, Jelle P Ruurda, Richard van Hillegersberg, Jingpu Wang, Paul Jeene, Lodewijk A A Brosens, Anne M May, Rob H A Verhoeven, Hanneke W M van Laarhoven, Nadia Haj Mohammad
European Journal of Cancer, 2025, vol. 224

Familial Mahvash disease with metastatic pancreatic NET and MEN1 mutations Jelka Kuiper, Wouter W de Herder, Yassine Ben Brahim, Marie-Louise F Van Velthuysen, Lodewijk A A Brosens, Richard A Feelders, Janneke G Langendonk, Ronald van Marion, Esther Korpershoek, Gunter Klöppel, Anja Wagner, Johannes Hofland
Endocrine-related cancer, 2025, vol. 32

Mucinous cystic neoplasms and simple mucinous cysts are two distinct precursors of pancreatic cancer Antonio Pea, Michele Bevere, Anastasios Gkountakos, Davide Pasini, Denise Fiorini, Andrea Mafficini, Stela Golovco, Michele Simbolo, Serena Pedron, Concetta Sciammarella, Paola Mattiolo, Aldo Mombello, Manuela Villanova, Carlotta Franzina, Francesca Masetto, Calogero Ciulla, Nicola Sperandio, Kohei Fujikura, Masha S Ahadi, Jaswinder S Samra, Amber L Johns, Joanne Verheij, Martijn W J Stommel, Hjalmar van Santvoort, Leonor Schubert Santana, Giuseppe Malleo, Michele Milella, Lodewijk A A Brosens, Laura D Wood, David K Chang, Riccardo De Robertis, Mirko D'Onofrio, Anthony J Gill, Roberto Salvia, Vincenzo Corbo, Rita T Lawlor, Aldo Scarpa, Claudio Luchini
Journal of Pathology, 2025, vol. 266, p.421-434

Tumour-intrinsic alterations and stromal matrix remodelling promote Wnt-niche independence during diffuse-type gastric cancer progression Lars J S Kemp, Jooske L Monster, Colin S Wood, Martijn Moers, Marjolein J Vliem, Antoine A Khalil, Nigel B Jamieson, Lodewijk A A Brosens, Liudmila L Kodach, Jolanda M van Dieren, Tanya M Bisseling, Rachel S van der Post, Martijn Gloerich
Gut, 2025, vol. 74, p.1219-1229

Multi-region Genomic Analysis of Human Pancreatic Mucinous Cystic Neoplasms Michael J Pflüger, Kohei Fujikura, Alicia M Braxton, Jae W Lee, Doreen M Zucha, Brian A Pedro, Davina Goodman, Jiayun Lu, Liping Jiang, Xiaobing Wang, Jiarun Zhu, Marco Dal Molin, Hao Wang, Lodewijk A A Brosens, Jin He, Satomi Kawamoto, Yuchen Jiao, Laura D Wood
Modern Pathology, 2025, vol. 38

Fellowships & Awards

2018: University of Verona Internationalization Program Stipend

2014: MLDS Career Development Grant

2013: UICC Yamagiwa-Yoshida Memorial international study grant

2013: Nijbakker-Morra Stichting Stipend

External positions

Patholoog - Gastrointestinal and pancreato-biliary pathology - Radboudumc