Profile photo Linda Joosten

Linda Joosten

PHD Candidate - Medical

Biography

Linda Joosten studied medicine at Utrecht University and obtained her medical degree in 2016.
She started her PhD programme at the Julius Center of the UMC Utrecht in January 2017. The focus of her research is to evaluate whether the impact of a strategy aimed at switching INR-guided vitamin K antagonist management to a NOAC-based treatment strategy (non-vitamin K antagonist oral anticoagulants) is superior in terms of the occurrence of major or clinically relevant non-major bleeding complications in frail elderly patients with atrial fibrillation (FRAIL-AF study). This multicenter pragmatic randomized controlled clinical trial is supervised by dr. Geert-Jan Geersing, dr. Frans Rutten and prof. dr. Arno Hoes. 
Linda Joosten will combine her PhD programme with the Postgraduate Master of Epidemiology at Utrecht University and the General Practice Vocational Training Programme in Utrecht.

Recent publications

Cumarine of DOAC bij kwetsbare ouderen met atriumfibrilleren? Linda P.T. Joosten, Sander van Doorn, Martin E.W. Hemels, Menno V. Huisman, Frans H. Rutten, Geert Jan Geersing
Nederlands Tijdschrift voor Geneeskunde, 2024, vol. 168
Clinical consequences of off-label reduced dosing of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation Linda P T Joosten, Rosanne van Maanen, Carline J van den Dries, Frans H Rutten, Arno W Hoes, Christopher B Granger, Martin E W Hemels, Geert-Jan Geersing, Sander van Doorn
Open Heart, 2023, vol. 10
Safety of Switching from a Vitamin K Antagonist to a Non-Vitamin K Antagonist Oral Anticoagulant in Frail Older Patients with Atrial Fibrillation Linda P T Joosten, Sander van Doorn, Peter M van de Ven, Bart T G Köhlen, Melchior C Nierman, Huiberdina L Koek, Martin E W Hemels, Menno V Huisman, Marieke Kruip, Laura M Faber, Nynke M Wiersma, Wim F Buding, Rob Fijnheer, Henk J Adriaansen, Kit C Roes, Arno W Hoes, Frans H Rutten, Geert-Jan Geersing
Circulation, 2023, vol. 149, p.279-289
Atrial fibrillation L. P.T. Joosten, A. R. de Boer, E. J.B. van Eerde, S. van Doorn, A. W. Hoes, M. L. Bots, F. H. Rutten, G. J. Geersing
Netherlands Heart Journal, 2022, vol. 30, p.459-465
Sex- and age specific association of new-onset atrial fibrillation with in-hospital mortality in hospitalised COVID-19 patients Joost A Offerhaus, Linda P T Joosten, Maarten van Smeden, Marijke Linschoten, Hidde Bleijendaal, Robert Tieleman, Arthur A M Wilde, Frans H Rutten, Geert-Jan Geersing, Carol Ann Remme,
IJC Heart and Vasculature, 2022, vol. 39, p.1-9
Cardiovascular vulnerability predicts hospitalisation in primary care clinically suspected and confirmed COVID-19 patients Florien S van Royen, Linda P T Joosten, Maarten van Smeden, Pauline Slottje, Frans H Rutten, Geert-Jan Geersing, Sander van Doorn
PLoS ONE, 2022, vol. 17