Jurgen Kuball

Full Professor

Strategic program(s):

Biography

Prof. Dr. Jürgen Kuball received his medical degree as hematologists at the University of Mainz, Germany, and was further trained at the Fred Hutchinson Cancer Center in Seattle, WA, USA. Prof. Kuball joined the Department of Hematology at the University Medical Center in Utrecht in The Netherlands in 2007 as hematologists and immunologist. He became a VIDI-laureate in 2010 and chairs the section applied & tumor-immunology within the laboratory of translation immunology. Since 2013 he is chairing the Department of Hematology (adults). His clinical activities are focusing on treating patients with hematological malignancies including stem cell transplantation. His clinical-translational efforts and patient care are driven by his role as Director of the Bone Marrow Transplantation Program at the University Medical Center Utrecht, as well as active membership of the leukemia working party and stem cell working party of HOVON. His current laboratory activities are focusing on the understanding of innate immune cells and their receptors to recognize malignant cells and virally infected cells as well as the genetic engineering of a transplant.

For more information on experimental and translational research please visit Kuball Laboratories

Strategic program(s):

Contact

jkuball@umcutrecht.nl

Pure profile

Research groups

Tumor Immunology

Research aim

Our research aims to revolutionise cancer treatment by advancing innovative immunotherapies, ensuring safer, more effective therapies, and improving patient outcomes, ultimately transforming lives through cutting-edge translational cancer research.

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Recent publications

All publications

Targeting pediatric cancers via T-cell recognition of the monomorphic MHC class I-related protein MR1 Annelisa M Cornel, Loutje van der Sman, Jip T van Dinter, Marta Arrabito, Ester Dunnebach, Marliek van Hoesel, Thomas A Kluiver, Ana P Lopes, Noël M M Dautzenberg, Linde Dekker, Jorik M van Rijn, Denise A M H van den Beemt, Juliane L Buhl, Aimee du Chatinier, Farnaz Barneh, Yuyan Lu, Luca Lo Nigro, Anja Krippner-Heidenreich, Zsolt Sebestyén, Jurgen Kuball, Esther Hulleman, Jarno Drost, Sebastiaan van Heesch, Olaf T Heidenreich, Weng Chuan Peng, Stefan Nierkens
Journal for ImmunoTherapy of Cancer, 2024, vol. 12

Allogeneic Hematopoietic Cell Transplantation for VEXAS Syndrome Carmelo Gurnari, Linda Koster, Laurien Greetje Antoinette Baaij, Mael Heiblig, Ibrahim Yakoub-Agha, Matthew Collin, Jakob R Passweg, Claude-Eric Bulabois, Anjum Bashir Khan, Michael Loschi, Fabrizio Carnevale-Schianca, Elena Crisà, Daniela Caravelli, Jürgen Kuball, Francesco Saraceni, Attilio Olivieri, Alessandro Rambaldi, Austin G Kulasekararaj, Patrick Hayden, Manuela Badoglio, Francesco Onida, Christof Scheid, Franco Franceschini, Arsene Mékinian, Sinisa Savic, Maria Teresa Voso, Joanna Drozd-Sokolowska, John Snowden, Kavita Raj, Tobias Alexander, Marie Robin, Raffaela Greco, Donal P McLornan
Blood Advances, 2024, vol. 8, p.1444-1448

Efficacy and safety of daratumumab in pure red cell aplasia after allogeneic transplantation Flores Gerrit Weverling, Mieke W H Roeven, Klaartje Kasper Nijssen, Annoek E C Broers, Elisabeth Dovern, Anna van Rhenen, Geerte van Sluis, Carin Hazenberg, Peter van Balen, Maria T Kuipers, Karen M K de Vooght, Linde M Morsink, Jürgen Kuball, Erfan Nur, Moniek Dewitte
Blood Advances, 2024, vol. 8, p.1683-1686

Reactivation of Multidrug-Resistant HSV-1 in a Post-Allogenic Hematopoietic Stem Cell Transplant Patient Shuxuan Zheng, Lidewij L.W. Rümke, Bruno Tello Rubio, Malbert R.C. Rogers, Geerte L. Van Sluis, Jürgen H.E. Kuball, Annelies Riezebos-Brilman, Robert Jan Lebbink, Frans M. Verduyn Lunel
Open Forum Infectious Diseases, 2024, vol. 11

Delayed Transfer of Immune Cells or the Art of Donor Lymphocyte Infusion (DLI) 2.0 J. H.Frederik Falkenburg, Christoph Schmid, Hans Joachim Kolb, Jürgen Kuball
2024, p.531-539

High-dose chemotherapy with autologous stem cell transplants in adult primary non-seminoma mediastinal germ-cell tumors. A report from the Cellular Therapy and Immunobiology working party of the EBMT S Secondino, M Badoglio, G Rosti, M Labopin, M Delaye, C Bokemeyer, C Seidel, E Kanfer, E Metafuni, J Finke, J-H Bouhris, C Kosmas, F Malard, A Pagani, J Kuball, U Koehl, A Ruggeri, U De Giorgi, P Pedrazzoli,
ESMO open, 2024, vol. 9

External positions

aandeelhouder - shareholder via Gadeta Founders - Century Therapeutics & Adeta

Chair - Chairing - Immunology Community Life Science

Secretary team member - bestuurslid - GoCART Coalition (EBMT/EHA)

Inkomsten licentie - Onderzoek - UMCU Holding

Commissie lid PPS commissie - grant indieningen voor KWF beoordelen - KWF

aandeelhouder - Receiving revenues from licensed patents via UMCU - UMC Holding

Chair legal and rgulatory affairs committee - Chair - EBMT

grant - grant ontvangen voor onderzoek - Novartis

Onderzoeker - grant ontvangen voor onderzoek - Miltenyi

bestuurslid - member general Board - HOVON

Patent holder multipe inventions licensed to Gadeta-follow up company Century Therapeuitcs &Miltenyi - Patent houder - Various