Jurgen Kuball

Full Professor

Strategic program(s):

Biography

Prof. Dr. Jürgen Kuball is Chair of the Department of Hematology, and Director of the Bone Marrow Transplantation Program at the UMC Utrecht Cancer Centre. His research activities focus on tumor immunology and the ATMP development of a next generation of engineered immune cells, with an emphasis on the therapeutic potential of individual receptors derived from γδT cells. His clinical activities focus around acute leukemia and allogeneic stem cell transplantation. He is an active member of European Society for Blood and Marrow Transplantation (EBMT), and has chaired the Legal Regulatory Affairs Committee of the EBMT since 2019.

Dr. Kuball received his medical degree in Hematology at the University of Mainz, Germany, and completed his post-doctoral fellowship at the Fred Hutchinson Cancer Center in Seattle, WA, USA. He joined the Department of Hematology at the UMC Utrecht in 2007 as a hematologist and immunologist. In 2010, he became a VIDI-laureate, and the chair of the Applied & Tumor-Immunology section within the Laboratory of Translation Immunology. He has chaired the Department of Hematology (adults) since 2013.

For more information on experimental and translational research please visit Kuball Laboratories

Strategic program(s):

Contact

jkuball@umcutrecht.nl

Pure profile

Research groups

Tumor Immunology

Research aim

Our research aims to revolutionise cancer treatment by advancing innovative immunotherapies, ensuring safer, more effective therapies, and improving patient outcomes, ultimately transforming lives through cutting-edge translational cancer research.

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Recent publications

All publications

Fertility management and outcomes after CAR T-cell therapy Giorgio Orofino, Isabel Sánchez-Ortega, Juana Schwartz Mota, Andrea Aroldi, Cristina Castilla-Llorente, Camille Bigenwald, Jean Hugues Dalle, Karima Yacouben, Roberta Di Blasi, Eugenio Galli, Victoria Grandage, Andrea Palasciano, Larry Bacon, Georg Nikolaus Franke, David Fandrei, Maximilian Merz, Lindsay George, Lucía Lopez-Corral, Judith S. Hecker, Daniele Mannina, Stefania Bramanti, Juan Alberto Martin Gonzalez, Núria Martínez-Cibrian, Soeren Lykke Petersen, Kamila Polgarova, Rachel Protheroe, Deborah Richardson, Ron Ram, Shlomo Elias, Bastian von Tresckow, Friedrich Stölzel, Iwona Streiss, Nicolas Vallet, Jeroen Knippenberg, Ana Alarcon Tomas, Simona Pagliuca, Florent Malard, Jürgen Kuball, Annalisa Ruggeri
EClinicalMedicine, 2026, vol. 96

Author Correction Thomas Kimman, Marta Cuenca, Ralph G Tieland, Dedeke Rockx-Brouwer, Jasmijn Janssen, Benjamin Motais, Anne Slomp, Corine Pleijte, Sabine Heijhuurs, Angelo D Meringa, Wendy Boschloo, Douwe M T Bosma, Sanne Kroos, Vania Lo Presti, Joost P G Sluijter, Stefan Nierkens, Niels Bovenschen, Jürgen Kuball, Alain van Mil, Monique C Minnema, Zsolt Sebestyén, Victor Peperzak
Nature Communications, 2026, vol. 17

Bridging therapy before CAR-T for multiple myeloma Nico Gagelmann, Maximilian Merz, Laurien G A Baaij, Linda Koster, Jorinde D Hoogenboom, Joanna Drozd-Sokolowska, Kavita Raj, Jürgen Kuball, Patrick J Hayden, Florent Malard, Laurent Garderet, Annalisa Ruggeri, Donal McLornan
Bone Marrow Transplantation, 2026, vol. 61, p.642-644

Outcomes of Patients Over 70 Years Treated with Brexu-cel for R/r Mantle Cell Lymphoma Nicole Santoro, Jarl Eduard Mooyaart, Urban Novak, Rachel Protheroe, Francis Ayuketang Ayuk, Peter Dreger, Tom van Meerten, Shankara Paneesha, Robin Sanderson, Ron Ram, Michael Northend, Edouard Forcade, Anne Huynh, Ibrahim Yakoub-Agha, Jorinde Desiree Hoogenboom, Maiana Hamdan Melo Coelho, Simona Pagliuca, Florent Malard, Jürgen Kuball, Anna Sureda, Ali Bazarbachi, Annalisa Ruggeri, Vanderson Rocha
Blood Advances, 2026, vol. 10, p.3135-3142

Commentary on "Comparative efficacy and safety of PSCA CAR-engineered Vδ1 γδ T cells for immunotherapy of pancreatic cancer" Dorine A de Bont, Trudy Straetemans, Zsolt Sebestyén, Jurgen Kuball
Journal for immunotherapy of cancer, 2026, vol. 14

αβT/CD19-depleted Allogeneic Stem Cell Transplantation in Adults with Inborn Errors of Immunity Janneke J H de Winter, Birtan M Ibrahimov, Frances A Verheij, Iris D Brinkman, Anniek H G Stuut, Pleun Schonewille, Marloes W Heijstek, Anna van Rhenen, Lotte E van der Wagen, Laura G M Daenen, Anke Janssen, Tim J A Hutten, Jürgen Kuball, Helen L Leavis, Moniek A de Witte
Journal of Clinical Immunology, 2026, vol. 46

Fellowships & Awards

American Association of Cancer Research-GlaxoSmithKline Scholar in Cancer Research Award (2001)
Stipendiat der Deutschen Krebshilfe (2005-2007)
Team Science recognition award of the „Society for Immunotherapy of Cancer“ to Jürgen Kuball and the University of Washington, USA (2010)
VIDI-Laureate ZonMW, The Netherlands (2010)

External positions

aandeelhouder - shareholder via Gadeta Founders - Century Therapeutics & Adeta

Chair - Chairing - Immunology Community Life Science

Secretary team member - bestuurslid - GoCART Coalition (EBMT/EHA)

Inkomsten licentie - Onderzoek - UMCU Holding

Commissie lid PPS commissie - grant indieningen voor KWF beoordelen - KWF

aandeelhouder - Receiving revenues from licensed patents via UMCU - UMC Holding

Chair legal and rgulatory affairs committee - Chair - EBMT

grant - grant ontvangen voor onderzoek - Novartis

Onderzoeker - grant ontvangen voor onderzoek - Miltenyi

bestuurslid - member general Board - HOVON

Patent holder multipe inventions licensed to Gadeta-follow up company Century Therapeuitcs &Miltenyi - Patent houder - Various