Kevin Kenna

Associate Professor

Strategic program(s):

Contact

k.p.kenna@umcutrecht.nl

Pure profile

Research groups

Neurogenetics

Research aim

Given increasing possibilities in gene-based therapies for ALS, the overall aim of my research is to elucidate the exact genetic contribution in every patient to liability to disease.

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Recent publications

All publications

Optimised machine learning for time-to-event prediction in healthcare applied to timing of gastrostomy in ALS Marcel Weinreich, Harry McDonough, Mark Heverin, Éanna Mac Domhnaill, Nancy Yacovzada, Iddo Magen, Yahel Cohen, Calum Harvey, Ahmed Elazzab, Sarah Gornall, Sarah Boddy, James J.P. Alix, Julian M. Kurz, Kevin P. Kenna, Sai Zhang, Alfredo Iacoangeli, Ahmad Al-Khleifat, Michael P. Snyder, Esther Hobson, Adriano Chio, Andrea Malaspina, Andreas Hermann, Caroline Ingre, Juan Vazquez Costa, Leonard van den Berg, Monica Povedano Panadés, Philip van Damme, Phillipe Corcia, Mamede de Carvalho, Ammar Al-Chalabi, Eran Hornstein, Eran Elhaik, Pamela J. Shaw, Orla Hardiman, Christopher McDermott, Johnathan Cooper-Knock
EBioMedicine, 2025, vol. 121

SpliPath enhances disease gene discovery in case-control analyses of rare splice-altering genetic variants Yan Wang, Charlotte van Dijk, Ilia Timpanaro, Paul Hop, Brendan Kenna, Maarten Kooyman, Eleonora Aronica, R. Jeroen Pasterkamp, Leonard H. van den Berg, Johnathan Cooper-Knock, Jan H. Veldink, Kevin Kenna, ,
Cell reports methods, 2025, vol. 5, p.1-12

Correction to Marleen Balvert, Johnathan Cooper-Knock, Julian Stamp, Ross P. Byrne, Soufane Mourragui, Juami van Gils, Stefania Benonisdottir, Johannes Schlüter, Kevin Kenna, Sanne Abeln, Alfredo Iacoangeli, Joséphine T. Daub, Brian L. Browning, Gizem Taş, Jiajing Hu, Yan Wang, Elham Alhathli, Calum Harvey, Luna Pianesi, Sara C. Schulte, Jorge González-Domínguez, Erik Garrisson, Michael P. Snyder, Alexander Schönhuth, Letitia M.F. Sng, Natalie A. Twine,
Genome Biology, 2025, vol. 26

Evaluation of a biomarker for amyotrophic lateral sclerosis derived from a hypomethylated DNA signature of human motor neurons Calum Harvey, Alicja Nowak, Sai Zhang, Tobias Moll, Annika K. Weimer, Aina Mogas Barcons, Cleide Dos Santos Souza, Laura Ferraiuolo, Kevin Kenna, Noah Zaitlen, Christa Caggiano, Pamela J. Shaw, Michael P. Snyder, Jonathan Mill, Eilis Hannon, Johnathan Cooper-Knock
BMC Medical Genomics, 2025, vol. 18

Considerations in the search for epistasis Marleen Balvert, Johnathan Cooper-Knock, Julian Stamp, Ross P. Byrne, Soufiane Mourragui, Juami van Gils, Stefania Benonisdottir, Johannes Schlüter, Kevin Kenna, Sanne Abeln, Alfredo Iacoangeli, Joséphine T. Daub, Brian L. Browning, Gizem Taş, Jiajing Hu, Yan Wang, Elham Alhathli, Calum Harvey, Luna Pianesi, Sara C. Schulte, Jorge González-Domínguez, Erik Garrisson, Bogdan Pasanuic, Sai Zhang, Sebastian Vorbrugg, Jasper van Bemmelen, Raghuram Dandinasivara, Magda Markowska, Mehmet Koyuturk, Andrea Guarracino, Paola Bonizzoni, Davide Bolognini, Joanna von Berg, Jasmijn Baaijens, Jorge Avila Cartes, Ammar Al-Chalabi, Michael P. Snyder, Alexander Schönhuth, Letitia M.F. Sng, Natalie A. Twine,
Genome Biology, 2024, vol. 25

Mechanism-free repurposing of drugs for C9orf72-related ALS/FTD using large-scale genomic data Sara Saez-Atienzar, Cleide dos Santos Souza, Ruth Chia, Selina N. Beal, Ileana Lorenzini, Ruili Huang, Jennifer Levy, Camelia Burciu, Jinhui Ding, J. Raphael Gibbs, Ashley Jones, Ramita Dewan, Viviana Pensato, Silvia Peverelli, Lucia Corrado, Joke J.F.A. van Vugt, Wouter van Rheenen, Ceren Tunca, Elif Bayraktar, Menghang Xia, Robert H. Baloh, Robert Bowser, Christopher B. Brady, Alexis Brice, James Broach, William Camu, Adriano Chio, John Cooper-Knock, Daniele Cusi, Carsten Drepper, Vivian E. Drory, Travis L. Dunckley, Eva Feldman, Mary Kay Floeter, Pietro Fratta, Glenn Gerhard, Summer B. Gibson, Jonathan D. Glass, Stephen A. Goutman, John Hardy, Matthew B. Harms, Terry D. Heiman-Patterson, Lilja Jansson, Janine Kirby, Hannu Laaksovirta, John E. Landers, Russell McLaughlin, Kevin Kenna, Leonard H. van den Berg, Jan H. Veldink, , , ,
Cell genomics, 2024, vol. 4