Kevin Kenna

Associate Professor

Strategic program(s):

Contact

kkenna@umcutrecht.nl

Pure profile

Research groups

Neurogenetics

Research aim

Given increasing possibilities in gene-based therapies for ALS, the overall aim of my research is to elucidate the exact genetic contribution in every patient to liability to disease.

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Recent publications

All publications

Rare and common genetic determinants of mitochondrial function determine severity but not risk of amyotrophic lateral sclerosis Calum Harvey, Marcel Weinreich, James A.K. Lee, Allan C. Shaw, Laura Ferraiuolo, Heather Mortiboys, Sai Zhang, Paul J. Hop, Ramona A.J. Zwamborn, Kristel van Eijk, Thomas H. Julian, Tobias Moll, Alfredo Iacoangeli, Ahmad Al Khleifat, John P. Quinn, Abigail L. Pfaff, Sulev Kõks, Joanna Poulton, Stephanie L. Battle, Dan E. Arking, Michael P. Snyder, Jan H. Veldink, Kevin P. Kenna, Pamela J. Shaw, Johnathan Cooper-Knock,
Heliyon, 2024, vol. 10

Systematic rare variant analyses identify RAB32 as a susceptibility gene for familial Parkinson’s disease Paul J. Hop, Dongbing Lai, Pamela J. Keagle, Desiree M. Baron, Brendan J. Kenna, Maarten Kooyman, Shankaracharya, Cheryl Halter, Letizia Straniero, Rosanna Asselta, Salvatore Bonvegna, Alexandra I. Soto-Beasley, , Zbigniew K. Wszolek, Ryan J. Uitti, Ioannis Ugo Isaias, Gianni Pezzoli, Nicola Ticozzi, Owen A. Ross, Jan H. Veldink, Tatiana M. Foroud, Kevin P. Kenna, John E. Landers
Nature Genetics, 2024, vol. 56, p.1371-1376

Genetic variability in sporadic amyotrophic lateral sclerosis Sien Hilde Van Daele, Matthieu Moisse, Joke J F A van Vugt, Ramona A J Zwamborn, Rick van der Spek, Wouter van Rheenen, Kristel Van Eijk, Kevin Kenna, Philippe Corcia, Patrick Vourc'h, Philippe Couratier, Orla Hardiman, Russell McLaughin, Marc Gotkine, Vivian Drory, Nicola Ticozzi, Vincenzo Silani, Antonia Ratti, Mamede de Carvalho, Jesús S Mora Pardina, Monica Povedano, Peter M Andersen, Markus Weber, Nazli A Başak, Chris Shaw, Pamela J Shaw, Karen E Morrison, John E Landers, Jonathan D Glass, Michael van Es, Leonard H van den Berg, Ammar Al-Chalabi, Jan Veldink, Philip Van Damme
Brain : a journal of neurology, 2023, vol. 146, p.3760-3769

Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS Paul J Hop, Ramona A J Zwamborn, Eilis Hannon, Gemma L Shireby, Marta F Nabais, Emma M Walker, Wouter van Rheenen, Joke J F A van Vugt, Annelot M Dekker, Henk-Jan Westeneng, Gijs H P Tazelaar, Kristel R van Eijk, Matthieu Moisse, Denis Baird, Ahmad Al Khleifat, Alfredo Iacoangeli, Nicola Ticozzi, Antonia Ratti, Jonathan Cooper-Knock, Karen E Morrison, Pamela J Shaw, A Nazli Basak, Adriano Chiò, Andrea Calvo, Cristina Moglia, Antonio Canosa, Maura Brunetti, Maurizio Grassano, Marc Gotkine, Yossef Lerner, Michal Zabari, Patrick Vourc'h, Philippe Corcia, Philippe Couratier, Jesus S Mora Pardina, Teresa Salas, Patrick Dion, Jay P Ross, Robert D Henderson, Michael A van Es, R Jeroen Pasterkamp, Russell L McLaughlin, Kevin P Kenna, Leonard H van den Berg, Jan H Veldink, Jan H Veldink, Leonard H van den Berg, Patrick Deelen, Patrick Deelen, Jan H Veldink,
Science translational medicine, 2022, vol. 14, p.1-15

Author Correction Wouter van Rheenen, Rick A A van der Spek, Mark K Bakker, Joke J F A van Vugt, Paul J Hop, Ramona A J Zwamborn, Niek de Klein, Harm-Jan Westra, Olivier B Bakker, Patrick Deelen, Gemma Shireby, Eilis Hannon, Matthieu Moisse, Denis Baird, Restuadi Restuadi, Egor Dolzhenko, Annelot M Dekker, Klara Gawor, Henk-Jan Westeneng, Gijs H P Tazelaar, Kristel R van Eijk, Maarten Kooyman, Ross P Byrne, Mark Doherty, Mark Heverin, Ahmad Al Khleifat, Alfredo Iacoangeli, Aleksey Shatunov, Nicola Ticozzi, Johnathan Cooper-Knock, Bradley N Smith, Marta Gromicho, Siddharthan Chandran, Suvankar Pal, Karen E Morrison, Pamela J Shaw, John Hardy, Richard W Orrell, Michael Sendtner, Thomas Meyer, Nazli Başak, Anneke J van der Kooi, Antonia Ratti, Roel A Ophoff, Michael A van Es, R Jeroen Pasterkamp, Russell L McLaughlin, Kevin P Kenna, Leonard H van den Berg, Jan H Veldink,
Nature Genetics, 2022, vol. 54, p.361-361

Telomere length analysis in amyotrophic lateral sclerosis using large-scale whole genome sequence data Ahmad Al Khleifat, Alfredo Iacoangeli, Ashley R. Jones, Joke J.F.A. van Vugt, Matthieu Moisse, Aleksey Shatunov, Ramona A.J. Zwamborn, Rick A.A. van der Spek, Johnathan Cooper-Knock, Simon Topp, Wouter van Rheenen, Brendan Kenna, Kristel R. Van Eijk, Kevin Kenna, Ross Byrne, Victoria López, Sarah Opie-Martin, Atay Vural, Yolanda Campos, Markus Weber, Bradley Smith, Isabella Fogh, Vincenzo Silani, Karen E. Morrison, Richard Dobson, Michael A. van Es, Russell L. McLaughlin, Patrick Vourc’h, Adriano Chio, Philippe Corcia, Mamede de Carvalho, Marc Gotkine, Monica Povedano Panades, Jesus S. Mora, Pamela J. Shaw, John E. Landers, Jonathan D. Glass, Christopher E. Shaw, Nazli Basak, Orla Hardiman, Wim Robberecht, Philip Van Damme, Leonard H. van den Berg, Jan H. Veldink, Ammar Al-Chalabi,
Frontiers in Cellular Neuroscience, 2022, vol. 16, p.1050596