Researchers Karijn Suijkerbuijk

Karijn Suijkerbuijk

Full Professor

Strategic program(s):

Biography

Karijn Suijkerbuijk is a translational medical oncologist with special interest in melanoma and immunotherapy. During her PhD, she performed research on tumor epigenetics in breast cancer in the lab of Professor Saraswati Sukumar at the Sidney Kimmel Cancer Center at Johns Hopkins University. Dr. Suijkerbuijk currently participates in multiple phase II and III clinical trials on immune checkpoint inhibitors. She published papers in Oncogene, Annals of Oncology and JNCI, received research grants from KWF and NWO and was awarded an ASCO Merit Award. Her current research focuses on clinical and immunological parameters assoaciated with immune related adverse events during checkpoint inhibition and clinicopathological factors associated with checkpoint inhibitor response.

Strategic program(s):

Contact

ksuijke2@umcutrecht.nl

Pure profile

Research groups

Molecular and cellular host-microbiota interactions

Research aim

Our research aims to unravel how the products from pathogenic and beneficial bacterial species within the intestinal microbiota contribute to human health and disease.

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Immunotherapy in solid tumors

Research aim

Our research aims at accomplishing cure and good quality of life for more and more patients with metastatic cancer by: - AI-based early identification of (non-)responders to current immunotherapy - new immunotherapies for non-responders - developing strategies to treat immunotherapy toxicity without compromising efficacy

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Recent publications

All publications

Gut microbiome and immune checkpoint inhibitor toxicity Rik J Verheijden, Mick J M van Eijs, Fernanda L Paganelli, Marco C Viveen, Malbert R C Rogers, Janetta Top, Anne M May, Janneke H H M van de Wijgert, Karijn P M Suijkerbuijk,
European Journal of Cancer, 2025, vol. 216

Corrigendum to "Adjuvant immunotherapy in older patients with stage III and resected stage IV melanoma A Özkan, E Kapiteijn, F van den Bos, M J B Aarts, F W P J van den Berkmortel, C U Blank, M Bloem, W A M Blokx, M J Boers-Sonderen, J J Bonenkamp, A J M van den Eertwegh, J W B de Groot, J B Haanen, C E Holtslag, G A P Hospers, D Piersma, R S van Rijn, A M Stevense-den Boer, K P M Suijkerbuijk, A A M van der Veldt, G Vreugdenhil, M W J M Wouters, J E A Portielje, N A de Glas
European Journal of Cancer, 2024, vol. 216

Deep learning on CT scans to predict checkpoint inhibitor treatment outcomes in advanced melanoma Laurens S Ter Maat, Rob A J De Mooij, Isabella A J Van Duin, Joost J C Verhoeff, Sjoerd G Elias, Tim Leiner, Wouter A C van Amsterdam, Max F Troenokarso, Eran R A N Arntz, Franchette W P J Van den Berkmortel, Marye J Boers-Sonderen, Martijn F Boomsma, Fons J M Van den Eertwegh, Jan Willem de Groot, Geke A P Hospers, Djura Piersma, Art Vreugdenhil, Hans M Westgeest, Ellen Kapiteijn, Ardine A De Wit, Willeke A M Blokx, Paul J Van Diest, Pim A De Jong, Josien P W Pluim, Karijn P M Suijkerbuijk, Mitko Veta
Scientific Reports, 2024, vol. 14

Impact of personalized response-directed surgery and adjuvant therapy on survival after neoadjuvant immunotherapy in stage III melanoma Irene L.M. Reijers, Alexander M. Menzies, Marta Lopez-Yurda, Judith M. Versluis, Elisa A. Rozeman, Robyn P.M. Saw, Winan J. van Houdt, Ellen Kapiteijn, Astrid A.M. van der Veldt, Karijn P.M. Suijkerbuijk, Hanna Eriksson, Geke A.P. Hospers, Willem M.C. Klop, Alejandro Torres Acosta, Lindsay Grijpink-Ongering, Maria Gonzalez, Anja van der Wal, Abrahim Al-Mamgani, Andrew J. Spillane, Richard A. Scolyer, Bart A. van de Wiel, Alexander C.J. van Akkooi, Georgina V. Long, Christian U. Blank
European Journal of Cancer, 2024, vol. 214

Mechanical HIFU and immune checkpoint inhibition Vera Mekers, Mirjam de Visser, Karijn Suijkerbuijk, Clemens Bos, Chrit Moonen, Roel Deckers, Gosse Adema
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 2024, vol. 41

Cutaneous melanoma T Amaral, M Ottaviano, A Arance, C Blank, V Chiarion-Sileni, M Donia, R Dummer, C Garbe, J E Gershenwald, H Gogas, M Guckenberger, J Haanen, O Hamid, A Hauschild, C Höller, C Lebbé, R J Lee, G V Long, P Lorigan, E Muñoz Couselo, P Nathan, C Robert, E Romano, D Schadendorf, V Sondak, K P M Suijkerbuijk, A C J van Akkooi, O Michelin, P A Ascierto,
Annals of oncology : official journal of the European Society for Medical Oncology, 2024, vol. 36, p.10-30

Fellowships & Awards

2007  Research year for residents (UU2007-3977) KWF
2008  Translational grant KWF (UU-2008-4217
2008  AGIKO stipend, ZonMW
2008  ASCO Merit Award

2018 ZonMW goed gebruik geneesmiddelen

External positions

research funding Genmab - AI onderzoekssamenwerking in Health Holland project dat door Genmab financieel wordt ondersteund - Genmab

ESMO melanoma faculty - expertise melanoom - European Society for Medical Oncology

Lid real world data working group ESMO - onderzoek patientcohorten - European Society for Medical Oncology

Lid wetenschappelijke adviesraad - ervaring onderzoek - Maarten van der Weijden foundation

Adviesraad stichting melanoom (sinds 2019) - Vanuit expertise als melanoombehandelaar - Stichting melanoom

Lid Data Safety Monitoring Committee CHOPIN studie (vanaf 2020; studie gesponsord door BMS) - onderzoekservaring immuuntherapie - LUMC

Voorzitter wetenschappelijke commissie - Kwaliteitsverbetering en onderzoek op het gebied van melanoomzorg - Dutch Melanoma Treatment Registry (DICA)

Adviesgroep kanker in de zwangerschap - Expertise melanoom en immuuntherapie - Adviesgroep kanker in de zwangerschap

Organisatie/voorzitter jaarlijks immuno-oncologie symposium - expertise en onderzoek immuunoncologie - Immuno-oncologie symposium

Bestuurslid Tumorfocusgroep melanoom - expertise melanoom - Tumorfocusgroep melanoom

medisch expert bij melanoom nascholing en congresjournaal ASCO/ESMO - expertise melanoom - Medtalks