Jeanine Roodhart

Associate Professor - medical

Strategic program(s):

Contact

jroodha2@umcutrecht.nl

Pure profile

Research groups

Translational oncology

Research aim

To develop, test, and implement novel therapeutic and diagnostic strategies to combat cancer by integrating fundamental and clinical research.

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Medical oncology colorectal cancer group

Research aim

To improve outcomes and quality of life for all patients with colorectal and anal cancer by developing and validating biomarkers, enhancing therapeutic strategies, refining patient selection, and studying real life treatment outcomes.

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Recent publications

All publications

The impact of mismatch repair status on accuracy of clinical staging in stage II/III rectal cancer in daily practice Renee A Lunenberg, Ingrid A Franken, Manon N G J A Braat, Marloes A G Elferink, Frederieke H van der Baan, Miriam Koopman, Geraldine Vink, Martijn P W Intven, Femke P C Sijtsma, Jeanine M L Roodhart
European Journal of Cancer, 2025, vol. 232

Impact of treatment history on drug resistance of metastatic colorectal cancer organoids Maarten A. Huismans, Lidwien P. Smabers, Sascha R. Brunner, Arne van Hoeck, Demi van de Kaa, Ingrid A. Franken, Emerens Wensink, Jan Koster, Richard Volckmann, Onno Kranenburg, Miriam Koopman, Hugo J.G. Snippert, Jeanine M.L. Roodhart
iScience, 2025, vol. 28

Clinical implications of whole genome sequencing in metastatic colorectal cancer Lidwien P Smabers, Hilde H Nienhuis, Wendy W J de Leng, Paul Roepman, Ilcan Ö A Ciftcibasi, G Emerens Wensink, Maarten A Huismans, Liselot B J Valkenburg-van Iersel, Geert A Cirkel, Elske C Gootjes, Henk M W Verheul, Frank J Jeurissen, Guus M Bol, Onno Kranenburg, Miriam Koopman, Edwin Cuppen, Jeanine M L Roodhart
Oncogene, 2025, vol. 44, p.4686-4698

Genomic distinctions in adolescent and young adult cancer Jeffrey van Putten, Lina H Lankhorst, Adrianus Johannes de Langen, Anthonie J van der Wekken, Jeanine Roodhart, Karen Bolhuis, Sjoukje F Oosting, Marloes van Dongen, Marleen Kok, Marjolein Geurts, Johan A F Koekkoek, Edwin Cuppen, Hilde H Nienhuis, Winette T A van der Graaf
Cancer Treatment Reviews, 2025, vol. 140

First-line PD-1 +/- CTLA-4 blockade in patients with deficient mismatch repair and/or microsatellite instability-high metastatic colorectal cancer Vincenzo Nasca, Gabriele Tinè, Julien Taieb, Sara Lonardi, Ben Boursi, Ofer Margalit, Lisa Salvatore, Romain Cohen, Javier Ros, Margherita Ambrosini, Koen Zwart, Jeanine Roodhart, Priya Jayachandran, Michael J Overman, Maria Elena Elez, Chiara Cremolini, David Tougeron, Miriam Koopman, Thierry André, Rosalba Miceli, Filippo Pietrantonio
The oncologist, 2025, vol. 30

Promoting large multinational academic clinical trials for gastrointestinal cancers in Europe J. Taieb, J. Seligmann, D. Modest, C. Girault, F. Rivera, E. Mahillo, P. Osterlund, P. Pfeiffer, D. Malka, C. Louvet, A. R. Siebenhuner, C. Morf, C. de la Fouchardiere, L. Monard, M. Koopman, G. Vink, I. Borbath, L. Dewever, R. Adams, A. Reinacher-Schick, F. Pietrantonio, S. Lonardi, T. Aparicio, C. Cremolini, Pierre Laurent-Puig, David Tougeron, Côme Lepage, Aziz Zaanan, Jean Marc Phelip, Laetitia Dahan, Claire Gallois, Rosine Guimbaud, Véronique Vendrely, Christopher Jones, Christopher Williams, David Cairns, Nancy Fernandes Desilva, Karen Geboes, Sabine Tejpar, Veerle Casneuf, Leen Mortier, Jeroen Dekervel, Timon Vandamme, Anne Demols, Geneviève Van Ooteghem, Sofie Demeulder, Michèle Van Hooren, Francesco Sclafani, Marc Peeters, Jeanine Roodhart,
ESMO open, 2025, vol. 10

External positions

Consulting Editor Framingham on Gastrointestinal Cancers - selectie meest relevante publicates ogv CRC voor publicatie als samenvatting voor vakgenoten. - framingham publishers

Board member on behalf of UMC Utrecht - lid - Hubrecht Organoid Technology

lid DSMB RADAR PANC studie - expertise als medisch oncoloog/onderzoek - UMC Utrecht

Member of the TC Bio - lid - UMC Utrecht

lid DSMB PELVEX2 studie - expertise als medisch oncoloog - Catharina Ziekenhuis

ONCODE clinical advisory board - expertise als medisch oncoloog/onderzoek - ONCODE

Clinical advisory board - adviserende rol - ONCODE

Editor patient information regarding colorectal cancer - adviseren - Kanker.nl

Steering committee - sturende rol - UPORT