Profile photo Jaqueline Lourdes Rios

Jaqueline Lourdes Rios

Assistant Professor

Biography

Jaqueline Lourdes Rios is an Assistant Professor at the University Medical Center Utrecht, in the Department of Orthopaedics. Her primary focus is on understanding the onset, mechanisms, and treatment strategies for osteoarthritis, with a particular interest in controlled drug release, patient stratification, and the transition to animal-free models. Her research spans in vitro, in vivo, and clinical trials, collaborating with national and international academic partners and industry to develop innovative therapeutic approaches.

In addition to her work in osteoarthritis, Dr. Rios also investigates implant infections, focusing on diagnostic and therapeutic strategies. Her team develops targeted delivery systems using aptamers and antibodies to transport radionuclides and other therapeutic agents to infection sites, with or without antibiotics, aiming for improved precision in diagnosis and treatment.

Dr. Rios earned her PhD in Kinesiology from the University of Calgary, Canada, where she explored exercise and dietary interventions in metabolic knee osteoarthritis models. She has secured multiple prestigious research grants, including funding from the NWO and the National Growth Fund, and has received numerous awards for her contributions to the field.

Beyond research, Dr. Rios is actively involved in teaching and mentoring within the Gradute School of Life Sciences master’s program and t PhD program at Utrecht University. Through her interdisciplinary approach, she aims to develop innovative therapies for osteoarthritis and implant infections, bridging fundamental research and clinical application to enhance patient outcomes.

Research groups

Utrecht Osteoarthritis Research - UROAR

Research aim

Our group studies osteoarthritis, from disease mechanisms to treatment strategies. Using a translational approach, we connect lab research to patient care, aiming to create effective diagnostic tools and patient-centered therapies.

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Recent publications

Towards stratification in osteoarthritis Girish Pattappa, Niclas G Karlsson, Bibiane Steinecker-Frohnwieser, Ali Mobasheri, Eiva Bernotiene, Frank Zaucke, Gundula Roesch, Ilona Uzieliene, Ingrid Meulenbelt, Jaqueline Lourdes Rios, Maria Kazakova, Marie-Astrid Boutet, Mona Dvir-Ginzberg, Valerija Groma, Zsuzsa Jenei-Lanzl, Yves Henrotin, Zhen Li, Sylvia Nürnberger, Cecilia Aulin,
BMC Rheumatology, 2025, vol. 9, p.1-15
Skeletal Muscle Composition and the Effects of Exercise and/or Prebiotic Fiber in Preventing Diet Related Morbidities Heiliane de Brito Fontana, Jaqueline Lourdes Rios, John Michaiel, Ruth A Seerattan, Venus Joumaa, David A Hart, Raylene A Reimer, Walter Herzog
Journal of functional morphology and kinesiology, 2025, vol. 10
In vitro and in vivo delivery of mRNA to joint cells using polymeric nanoparticles Adriano P Pontes, Jaqueline Lourdes Rios, Mattie Rijker, Kelly Warmink, Shreya Gudi, Francisco Conceição, Björn Meij, Tim J M Welting, Liliana Moreira Teixeira, Jaap Rip, Laura B Creemers
Acta Biomaterialia, 2025, vol. 202, p.418-434
The effect of a low transition temperature mixture for enhanced bioavailability of celecoxib in combination with hyaluronic acid in a rat model with post-traumatic knee osteoarthritis Ana Roda, Jaqueline Lourdes Rios, Yeter Dilek, Kelly Warmink, Remei Escudero, Katrin A Muenzebrock, Jie Du, Zhiming Wu, Niels Eijkelkamp, Alexandre Paiva, Ana Rita C Duarte, Laura B Creemers
Biomedicine & pharmacotherapy, 2025, vol. 189
Mesenchymal stromal cell injections for osteoarthritis Marta Santolini, Jaqueline Lourdes Rios, Roel J H Custers, Laura B Creemers, Jasmijn V Korpershoek
The Knee, 2025, vol. 56, p.267-275
Antibody and aptamer-based therapies for osteoarthritis Huaizhi Chen, Zijian Ye, Jasmijn V. Korpershoek, Laura B. Creemers, Harrie Weinans, Jaqueline Lourdes Rios
Molecular therapy. Nucleic acids, 2025, vol. 36