Profile photo Janetta Top

Janetta Top

Assistant Professor

Strategic program(s):

Research groups

Microbial genomics and metagenomics

Research aim

We develop novel genomic methods for reconstructing and tracking antimicrobial resistance genes by building bioinformatics tools to facilitate data analysis of massive sequence data sets of pathogens and microbiomes.

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Translational microbiomics

Research aim

Our aim is to translate human microbiome knowledge to improved diagnostic tests and clinical interventions by incorporating systems biology into clinical epidemiological studies, conducting mechanistic laboratory studies, and linking the two.

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Recent publications

YajC, a predicted membrane protein, promotes Enterococcus faecium biofilm formation in vitro and in a rat endocarditis model Janetta Top, Xinglin Zhang, Antoni P.A. Hendrickx, Sjef Boeren, Willem van Schaik, Johannes Huebner, Rob J.L. Willems, Helen L. Leavis, Fernanda L. Paganelli
FEMS Microbes, 2024, vol. 5