Profile photo Jaap Kappelle

Jaap Kappelle

Full Professor

Strategic program(s):

Biography

Jaap Kappelle was registered as a clinical neurologist in 1988. He obtained his PhD degree in Utrecht (1990) with Jan van Gijn. He carried out postdoctoral research at the University of Iowa, Iowa City, USA (1991) and the John P. Robarts Research Institute, London (Ontario) Canada (1998). He was appointed assistant professor at the University Utrecht in 1988, associate professor in 1994 and full professor in 2000.  He is former head of the department of cerebrovascular diseases of the University Medical Centre (UMC) Utrecht (2011-2020). As of 2020 he has been appointed medicale safety officer of the UMCU.

His research is embedded in the research lines 'Circulatory Health' and 'Brain' of the UMCU in close collaboration with the departments of neurosurgery, radiology, vascular medicine, vascular surgery, rehabilitation, clinical epidemiology, primary health care and neuropsychology. His current line of research concerns stroke, in particular the diagnosis, treatment and prognosis of patients with TIA or ischaemic stroke. As part of his research activities he is member of steering committees of reserrch programs embedded in 'Cardio-Vasculair Onderzoek Nederland' and serves as expert adjucation panelmeber of several clinical trials.

He is founding president of the Dutch Neurovascular Society. He is a member of the education committee if the Dutch Neurological Society and Dutch delegate for stroke of the European Association of Neurology. Besides his regular education duties in the UMC Utrecht, he is member of the board of supervisors of the Medical student Societÿ 'MSFU SAMS)

Jaap Kappelle is member elect of the European Stroke Council, the World Stroke Organisation and premium professional silver heart memeber  of the American Heart Associatiuon. He holds also memberships of the Dutch Society of Neurology, the Dutch Vascular Society, the European Association of Neurology, the Royal Dutch Association of Medicine and the Dutch Society of Medical Litigation Assessments.

He serves as neutral expert for different courts, insurance companies and health care organisations. 

Research line

Cerebrovascular diseases

publications

https://pubmed.ncbi.nlm.nih.gov/?term=Kappelle+LJ&sort=pubdate

https://pubmed.ncbi.nlm.nih.gov/?term=Kapelle+LJ&sort=pubdate

https://pubmed.ncbi.nlm.nih.gov/?term=Kappelle+J&sort=pubdate

Strategic program(s):

Contact

Recent publications

Orthostatic hypotension, cognition and structural brain imaging in hemodynamically impaired patients Naomi L.P. Starmans, Frank J. Wolters, Anna E. Leeuwis, Esther E. Bron, Jeroen de Bresser, Hans Peter Brunner-La Rocca, Julie Staals, Majon Muller, Geert Jan Biessels, L. Jaap Kappelle,
Journal of the Neurological Sciences, 2024, vol. 461
Association between lower extremity arterial calcification and coronary arterial calcification in a population at increased risk of cardiovascular disease Romain Meer, Anna G. Hoek, Emma J. Bouman, Teddo Doesburg, Petra J.M. Elders, P. A. de Jong, Joline Beulens, M. J. Cramer, H. M. Nathoe, M. G. van der Meer, G. J. de Borst, M. Teraa, M. L. Bots, M. van Smeden, M. H. Emmelot-Vonk, P. A. de Jong, A. T. Lely, N. P. van der Kaaij, L. J. Kappelle, Y. M. Ruigrok, M. C. Verhaar, J. A.N. Dorresteijn, F. L.J. Visseren,
BMJ Open Diabetes Research and Care, 2024, vol. 12
Safety and efficacy of active blood-pressure reduction to the recommended thresholds for intravenous thrombolysis in patients with acute ischaemic stroke in the Netherlands (TRUTH) Thomas P. Zonneveld, Sarah E. Vermeer, Erik W. van Zwet, Adrien E.D. Groot, Ale Algra, Leo A.M. Aerden, Kees C.L. Alblas, Frank de Beer, Paul J.A.M. Brouwers, Koen de Gans, H. Maarten A. van Gemert, Bart C.A.M. van Ginneken, Gerke S. Grooters, Patricia H.A. Halkes, Tonny A.M.H.G. van der Heijden-Montfroy, Korné Jellema, Sonja W. de Jong, Harry Lövenich-Ciccarello, Willem D.M. van der Meulen, Edwin W. Peters, Taco C. van der Ree, Michel J.M. Remmers, Edo Richard, Jörgen M.P. Rovers, Ritu Saxena, Sander M. van Schaik, Wouter J. Schonewille, Tobien A.H.C.M.L. Schreuder, Els L.L.M. de Schryver, Wouter J. Schuiling, Fianne H. Spaander, Julia H. van Tuijl, Marieke C. Visser, Sanne M. Zinkstok, Elles Zock, Diederik W.J. Dippel, L. Jaap Kappelle, Robert J. van Oostenbrugge, Yvo B.W.E.M. Roos, Frederique H. Vermeij, Marieke J.H. Wermer, H. Bart van der Worp, Paul J. Nederkoorn, Nyika D. Kruyt
The Lancet Neurology, 2024, vol. 23, p.807-815
Alzheimer's Disease and Cognitive Decline in Patients with Cardiovascular Diseases Along the Heart-Brain Axis Calvin Trieu, Argonde C. van Harten, Anna E. Leeuwis, Lieza G. Exalto, Astrid M. Hooghiemstra, Inge M.W. Verberk, Cor P. Allaart, Hans Peter Brunner-La Rocca, L. Jaap Kappelle, Robert J. van Oostenbrugge, Geert Jan Biessels, Charlotte E. Teunissen, Wiesje M. van der Flier,
Journal of Alzheimer's Disease, 2024, vol. 98, p.987-1000
Temporal Trends and Determinants of Stroke Risk in Patients With Medically Treated Asymptomatic Carotid Stenosis Michiel H F Poorthuis, Yoel Solomon, Reinier A R Herings, Frank L J Visseren, L Jaap Kappelle, Michiel L Bots, Ina Rissanen, Gert J de Borst
Stroke, 2023, vol. 54, p.1735-1749
Twenty-four hour blood pressure variability and the prevalence and the progression of cerebral white matter hyperintensities Naomi Lp Starmans, Frank J Wolters, Annebet E Leeuwis, Esther E Bron, Hans-Peter Brunner La Rocca, Julie Staals, Geert Jan Biessels, L Jaap Kappelle,
Journal of Cerebral Blood Flow and Metabolism, 2023, vol. 43, p.801-811

External positions

beoordeling casuïstiek op neurologisch gebied - zie boven - Neuro Orthopedisch Centrum