Profile photo Houben

Houben

Assistant Professor - medical

Strategic program(s):

Biography

Michiel was trained as a medical doctor (2002) and pediatrician (2010) and as a clinical epidemiologist (2009) at the UMC Utrecht. In 2011 he obtained his PhD on his thesis entitled: RSV Bronchiolitis in Healthy Term Infants, Pathogenesis and Prediction. Since 2010 he works as a general pediatrician in the Wilhelmina Children’s Hospital (UMC Utrecht) and since 2014 he is head of the section of general en social pediatrics. He is the pediatrician and coordinator of the 22q11.2 deletion syndrome childhood outward patient clinic and studies the heterogeneity and prognostic factors of this syndrome, in close collaboration with colleagues of other pediatric, surgery, psychiatric, psychology and genetics specialties. He is also involved in several further studies on the healthy term birth (amniotic fluid) cohort from his PhD trajectory.

Recent publications

Early Sagittal Shape of the Spine Predicts Scoliosis Development in a Syndromic (22q11.2DS) Population A Prospective Longitudinal Study Steven de Reuver, Jelle F. Homans, Michiel L. Houben, Tom P.C. Schlösser, Keita Ito, Moyo C. Kruyt, René M. Castelein
Journal of Bone and Joint Surgery, 2024, vol. 106, p.2256-2263
Identification of a pathogenic deep intronic variant in ATRX ends a diagnostic odyssey Jasper J. van der Smagt, Angeliki P. Lampri, Iris de Lange, Mariëlle Alders, Michiel L. Houben, Marco J. Koudijs, Richard H. van Jaarsveld
European Journal of Medical Genetics, 2024, vol. 69
A comprehensive overview of neuropsychiatric symptoms in adolescents with 22q11.2 deletion syndrome I. Selten, J. Blok, T. Boerma, A. A.A.M.J. Djelantik, M. Houben, F. Wijnen, J. Zinkstok, J. A.S. Vorstman, A. M. Fiksinski
Journal of Intellectual Disability Research, 2024, vol. 69, p.113-126
Bi-allelic variants in NAE1 cause intellectual disability, ischiopubic hypoplasia, stress-mediated lymphopenia and neurodegeneration Irena J.J. Muffels, Imre F. Schene, Holger Rehmann, Maarten P.G. Massink, Maria M. van der Wal, Corinna Bauder, Martha Labeur, Natalia G. Armando, Maarten H. Lequin, Michiel L. Houben, Jaques C. Giltay, Saskia Haitjema, Albert Huisman, Fleur Vansenne, Judith Bluvstein, John Pappas, Lala V. Shailee, Yuri A. Zarate, Michal Mokry, Gijs W. van Haaften, Edward E.S. Nieuwenhuis, Damian Refojo, Femke van Wijk, Sabine A. Fuchs, Peter M. van Hasselt
American Journal of Human Genetics, 2023, vol. 110, p.146-160
Grammatical skills of Dutch children with 22q11.2 Deletion Syndrome in comparison with children with Developmental Language Disorder Tessel Boerma, Emma Everaert, Dinte Vlieger, Maaike Steggink, Iris Selten, Michiel Houben, Jacob Vorstman, Ellen Gerrits, Frank Wijnen
Frontiers in Communication, 2023, vol. 8

Fellowships & Awards

  • 2011-12 PhD Curriculum of Training Upcoming Leaders in Pediatric Science (TULIPS), competitive selection
  • 2011 NVK Masterclass, Prof Dr B Prakken, Prof Dr HJ Verkade, competitive selection

  • 2007 NVK Young Investigators, award best poster presentation

  • 2005 ESPID Fellowship Award

  • 2000 UMC Utrecht Students’ Scientific meeting, 2nd price for oral presentation

  • 1992 Theoretical Mathematics Olympiads, team competition, national winner

  • 1992 Applied Mathematics Olympiads, team competition, national winner

External positions

Bestuurslid NVK-sectie Erfelijke en Aangeboren Aandoeningen (EAA) - Algemeen kinderarts met dit aandachtsgebied - Ned. Ver. Kindergeneeskunde

Member of the Multidisciplinary advisory board of the Dutch patient support group “Steun 22Q11" - Kinderarts & medisch coordinator van 22q11-polikliniek WKZ / UMCU - Dutch patient support group “Steun 22Q11"